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The map label for this gene is rnhB [H]

Identifier: 53719754

GI number: 53719754

Start: 2575277

End: 2575921

Strand: Reverse

Name: rnhB [H]

Synonym: BPSL2145

Alternate gene names: 53719754

Gene position: 2575921-2575277 (Counterclockwise)

Preceding gene: 53719755

Following gene: 53719753

Centisome position: 63.22

GC content: 69.3

Gene sequence:

>645_bases
ATGGCGACGACGCGCAAACCCCGCGGCGGGGCCGGCGGCGCGACCCAGCCCGCGCTCGATTTCGACGCGCCGGGCGAGAT
CGTCTGCGGCGTCGACGAAGCCGGGCGCGGCCCGCTCGCCGGGCCCGTCGTCGCGGCGGCCGTCGTGCTCGATCCGGCGC
GGCCGATCGTCGGCCTCGACGATTCGAAGGCGTTGTCCGCGAAGAAGCGCGAGCGGCTCTTCGACGAAATCGTCGTGCAT
GCGCTCGCGTACAGCGTCGCCTCGGCGAGCGTCGAGGAAATCGACAGCCTCAACATCCTGCATGCGACGATGCTCGCGAT
GAAGCGCGCAGTCGAAGGGCTCTCGGTGCTGCCGACGCTCGCGAAGATCGACGGCAACCGCTGCCCGATGCTCGCGATCC
GCAGCGAAGCGATCGTCGGCGGCGACGCGCTCGTGCCGAGCATCTCGGCCGCGTCGATCCTCGCGAAGGTCACGCGCGAC
CGGATGCTCGTCGAACTGCATCAGCAGTTTCCGATGTACGGTTTCGATGCGCACGCGGGCTACGGTACGCCGCAGCATCT
GGCCGCCTTGCGCGAGCATGGGCCGTGCGAGCATCACCGCCGCTCGTTCGCGCCGGTGCGCGAAGCCTTCGATTTGATTC
GATGA

Upstream 100 bases:

>100_bases
CCGACATTTTCACCGACATGCATCTCGCGTTGCGCCAGAATACCGCGCAGCGCGCGGCCGAGGCCGTCGCGCGCGTGATC
GACAGCAGGAAGCCGCGCTG

Downstream 100 bases:

>100_bases
AAGCGATCACTTCCCGCGACAATCCGCTGTACAAGCGCCTGAAGGCGCTCGCGGGATCGACGCACCAGCAGCGGCGCGGC
GAGCAGGCGCTCCTCGAAGG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVVH
ALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRD
RMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR

Sequences:

>Translated_214_residues
MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVVH
ALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRD
RMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
>Mature_213_residues
ATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVVHA
LAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDR
MLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=195, Percent_Identity=58.974358974359, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17536263, Length=186, Percent_Identity=35.4838709677419, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 22657; Mature: 22526

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
DSKALSAKKRERLFDEIVVHALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAG
HHCCCCCCCEEEECCCHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLD
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
DSKALSAKKRERLFDEIVVHALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAG
HHCCCCCCCEEEECCCHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA