Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 53719618

GI number: 53719618

Start: 2390396

End: 2391952

Strand: Reverse

Name: degP [H]

Synonym: BPSL2006

Alternate gene names: 53719618

Gene position: 2391952-2390396 (Counterclockwise)

Preceding gene: 53719619

Following gene: 53719616

Centisome position: 58.7

GC content: 72.13

Gene sequence:

>1557_bases
GTGTCTCGTCAAACGCTTGGCCGCGCCCTGATTCACGTTGCAGCGCTCGGGGCGGTGCTTGCCGGCTTCGCTTGCCTGCA
GCCGACGCCACTCGCCGCGGGTACGCTGCAATCGCCGGCGAAGGCGAAGCGAATCGCGCAGATCGGCGCCGCGGGGCCGG
TCGATTTTCCCACGCTCGTCGAGCGATACGGGCCCGCCGTCGTCAGCGTGAGCGTGCCTGCGCAGGATCCGCAGATGTCG
GCGTCCGGCCTCGAGGCGCTCGATCCCGACGATCCGTTCTTCGCCTACTTCAAATCCGCCGCCACGCAGCCCGCACTGTC
GCCGGAGAACGGGCCGCGCGCGATGGCGGGCGCCGGATCCGGTTTTATCGTCGGCGCCGACGGGATCATCCTGACGACCG
CGTACGTGGTCGGGCAGGCGAGCGAGGCGACGGTTCGCCTGATCGACCGGCGCGAATTCAAGGCGCGGGTGCTGGCCGTC
GATGATTCGAGCGATGTGGCCGTGTTGCAGATCGACGCGACGAAGCTGCCGACGGTGCGGCTCGGCGATTCGTCCCGGGT
GCGCACGGGCGAGCCGGTGCTGACGATCGGCACGCCGGACGGCTCGGCGAACACGGTGACGACGGGCATCGTCAGCGCGA
CGGCGCGCATGTTGCCCGACGGCGGCCGCTTTCCGTTCTTCCAGACCGACGTGACCGGCAACCTCGACAACTCGGGCGGC
CCGGTGTTCAACCGCGCGGGCGAGGTGATCGGCATCGACGTGCAGATCTACGGCAGCGGCGAGCGCAATCCGGGCGTGAC
GTTTGCGATTCCGATCGACATGGCGATGAAGGTGCGTGCGCAGGTGCTGCAGGCGCAGCGCCAGGCGCGGCAGCAGGCGC
AGCCGCCGATGCAACAGGCGCAACAGGCGCAACAAGCGCCGCCCGCGGCGGCGCAGAACGCGCTGGGCGTCGACGCGCAG
GACGTCGGTCCGGGGCTCGCGGCGGCGTTCGGCCTGCCGCGGCCGGCGGGCGCGCTTGTCAATGCAGTGGAGCCGGGGTC
GCCGGCGGCGGCGGTCGGGCTGAAGCCGGGCGACGTGATCGTGCAGATCGGCGATCGGCCGCTCGGCCGCTCGGCGGAAC
TGGCCGGCGACCTCGCGGCGCTGCCGCCCGGGGCGAGCGCGCCGATCACGCTGATCCGCAACCGGATGCCGATGACGGTG
ATGCTCAGCTCCGGCGCGGCCGCGAGCGCGCCGACAGGCGCGACCGCATCGCCGGGCAATGCGGCCGCCGGCCGCAGCGA
GACGGGCGGCGCGGACCGCCTGGGCCTGACGATGCATCCGCTGACGGACGACGAGCGGCGCTCGACGGGATTGCCCGTCG
GCATGGTGGTCGATGCGGTGCGCGGGCCGGCGGCGAACGCGGGGATTCGGCCGGGCGACGTCGTGCTGGAGCTCGACGAT
ACGCTGATCGAGACGCCGGACATGGTGCCGGCGCTGGAGGCGAAGGCGGGGAAGGTGGTCGCGGTGCTGATTCAGCGGGG
GAGCGAGCGCAGGTTCGTGTCGGTGAAGGCGCGGTGA

Upstream 100 bases:

>100_bases
TTCGCCGGGCGCTATGCAATAATCGATTCATCAGTGCGTGCTAGTCCTTCGCGCGTCGCGCGGCGGGCCTCTGGCATAAC
GACTGCCTGGGAGGTGCACT

Downstream 100 bases:

>100_bases
AGGCGCGGTGAAGCCGCGATGGAGGCGAAGCGCGCCGCCGGCGGTGCGCCATGCACCGGGAGCCGGCGTCGCGGCAGCGC
GGCGGCGCATGGCTCGCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSRQTLGRALIHVAALGAVLAGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLVERYGPAVVSVSVPAQDPQMS
ASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGSGFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAV
DDSSDVAVLQIDATKLPTVRLGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQAQQAQQAPPAAAQNALGVDAQ
DVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVIVQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTV
MLSSGAAASAPTGATASPGNAAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR

Sequences:

>Translated_518_residues
MSRQTLGRALIHVAALGAVLAGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLVERYGPAVVSVSVPAQDPQMS
ASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGSGFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAV
DDSSDVAVLQIDATKLPTVRLGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQAQQAQQAPPAAAQNALGVDAQ
DVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVIVQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTV
MLSSGAAASAPTGATASPGNAAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR
>Mature_517_residues
SRQTLGRALIHVAALGAVLAGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLVERYGPAVVSVSVPAQDPQMSA
SGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGSGFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAVD
DSSDVAVLQIDATKLPTVRLGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGGP
VFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQAQQAQQAPPAAAQNALGVDAQD
VGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVIVQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTVM
LSSGAAASAPTGATASPGNAAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDDT
LIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=271, Percent_Identity=35.7933579335793, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7019477, Length=259, Percent_Identity=35.1351351351351, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI22129776, Length=274, Percent_Identity=32.4817518248175, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI24308541, Length=271, Percent_Identity=31.7343173431734, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1789629, Length=472, Percent_Identity=30.9322033898305, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1786356, Length=472, Percent_Identity=27.9661016949153, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789630, Length=290, Percent_Identity=31.3793103448276, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646839, Length=301, Percent_Identity=31.5614617940199, Blast_Score=128, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52768; Mature: 52636

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQTLGRALIHVAALGAVLAGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
ERYGPAVVSVSVPAQDPQMSASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGS
HHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCC
GFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAVDDSSDVAVLQIDATKLPTVR
CEEEECCCCEEEEEHHHCCCCCCEEEEEHHHCCEEEEEEEECCCCEEEEEECCCCCCEEE
LGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
ECCCCCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQA
CCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QQAQQAPPAAAQNALGVDAQDVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVI
HHHHHCCCHHHHHCCCCCHHHCCCCHHHHHCCCCCCHHHHCCCCCCCCCEEECCCCCCEE
VQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTVMLSSGAAASAPTGATASPGN
EEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCC
AAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
CCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECC
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR
HHHCCCCCCCHHHCCCCCEEEEEECCCCCCEEEEEECC
>Mature Secondary Structure 
SRQTLGRALIHVAALGAVLAGFACLQPTPLAAGTLQSPAKAKRIAQIGAAGPVDFPTLV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
ERYGPAVVSVSVPAQDPQMSASGLEALDPDDPFFAYFKSAATQPALSPENGPRAMAGAGS
HHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCC
GFIVGADGIILTTAYVVGQASEATVRLIDRREFKARVLAVDDSSDVAVLQIDATKLPTVR
CEEEECCCCEEEEEHHHCCCCCCEEEEEHHHCCEEEEEEEECCCCEEEEEECCCCCCEEE
LGDSSRVRTGEPVLTIGTPDGSANTVTTGIVSATARMLPDGGRFPFFQTDVTGNLDNSGG
ECCCCCCCCCCCEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCC
PVFNRAGEVIGIDVQIYGSGERNPGVTFAIPIDMAMKVRAQVLQAQRQARQQAQPPMQQA
CCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHH
QQAQQAPPAAAQNALGVDAQDVGPGLAAAFGLPRPAGALVNAVEPGSPAAAVGLKPGDVI
HHHHHCCCHHHHHCCCCCHHHCCCCHHHHHCCCCCCHHHHCCCCCCCCCEEECCCCCCEE
VQIGDRPLGRSAELAGDLAALPPGASAPITLIRNRMPMTVMLSSGAAASAPTGATASPGN
EEECCCCCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCC
AAAGRSETGGADRLGLTMHPLTDDERRSTGLPVGMVVDAVRGPAANAGIRPGDVVLELDD
CCCCCCCCCCCCCCCEEECCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECC
TLIETPDMVPALEAKAGKVVAVLIQRGSERRFVSVKAR
HHHCCCCCCCHHHCCCCCEEEEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]