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The map label for this gene is murR [H]

Identifier: 53719602

GI number: 53719602

Start: 2372102

End: 2372983

Strand: Reverse

Name: murR [H]

Synonym: BPSL1990

Alternate gene names: 53719602

Gene position: 2372983-2372102 (Counterclockwise)

Preceding gene: 53719610

Following gene: 53719601

Centisome position: 58.24

GC content: 67.35

Gene sequence:

>882_bases
ATGGACGACACGACCCCCCCGGAGACGCCGGCCGTCGACGATCTGCTGCAACGGATCGCCGGCGCCTACGACACGCTGCC
GCGCCAGTTGAAGCGCATCGCCTCTTATATCGACGAGCACCGCTCGAGCGTGATGATGGACCGCACGAGCGACATCGCGC
AGCGCTGCGGCGTGCACCCGTCCGCCGTCGTGCGCTTCGCGCAGCGCTTCGGCTTTTCCGGCTTTTCCGATCTGCAGGCG
GTGTTCAAGGACGCCTATACGGGCCAGAACCCGACCGTGCAGAGCTACCAGCAGCGCATTCGCAGCCTGATCGACGGCGA
GGCCGGCCCGATGACGGGCGGTGCGGTCGCGCGGCAGTTCATCGACGCGTCGCGCGCGGGGCTCGACGAGCTCGCGGCGG
GCCTCGACGACGACCAGTTCGACGCGGCCGTGACGATGCTCGAGCGCGCGGAGAACATCTACGTGGTCGGCGTGCGGCGC
TCGTTTCCGGTCGCGAGCTACATCGTCTACGCGCTGCAGCATACGGCCAAGCGCGTGCACCTCGTGTCCGGCCTCGGCGG
CATGTACCGCGAGCAGATCCGCAGCGTGAAGAAGGGCGACGTGGTGATCGCGATCAGCTTCGCGCCGTACGGCAAGGAAA
CGCAGTACTGCCTGCGCGCCGCGCGCCACAACCACGCGCAGACGCTCGTCGTCACCGACAGCCGCCTGTCGCCGCTCGCG
CGCGACGCGAGCGCCCATTTGCTCGTGAAGGAGGGCAGCGCGTTCGCGTTCCGCTCGCTCACGAGCACGATCTGCCTGTG
CCAGGCGCTGTTCATCGCGCTTGCGTACCGGCTCGAGTTGAACGTGGAAGAAGTCAAGGACATTGGAGGATACGATGACT
AA

Upstream 100 bases:

>100_bases
GTGCCTATACTCGCTGCACGACAAGACACGGAGCAAGGCGTCCGGCGCTTGCCCGCCGCGCGCGACGCGCGTGGGCGGGC
GGCCGGGCCGACGGAGCGAC

Downstream 100 bases:

>100_bases
CGCAGCACCGACGATCGACGTCGCCGTGTTCGGCGCCGGGCGCATCGGCCGCATTCATGCGGGCAATCTCGCGCGCCGGC
CCGGCGTGCGCCTGAAGTAC

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDDTTPPETPAVDDLLQRIAGAYDTLPRQLKRIASYIDEHRSSVMMDRTSDIAQRCGVHPSAVVRFAQRFGFSGFSDLQA
VFKDAYTGQNPTVQSYQQRIRSLIDGEAGPMTGGAVARQFIDASRAGLDELAAGLDDDQFDAAVTMLERAENIYVVGVRR
SFPVASYIVYALQHTAKRVHLVSGLGGMYREQIRSVKKGDVVIAISFAPYGKETQYCLRAARHNHAQTLVVTDSRLSPLA
RDASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDIGGYDD

Sequences:

>Translated_293_residues
MDDTTPPETPAVDDLLQRIAGAYDTLPRQLKRIASYIDEHRSSVMMDRTSDIAQRCGVHPSAVVRFAQRFGFSGFSDLQA
VFKDAYTGQNPTVQSYQQRIRSLIDGEAGPMTGGAVARQFIDASRAGLDELAAGLDDDQFDAAVTMLERAENIYVVGVRR
SFPVASYIVYALQHTAKRVHLVSGLGGMYREQIRSVKKGDVVIAISFAPYGKETQYCLRAARHNHAQTLVVTDSRLSPLA
RDASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDIGGYDD
>Mature_293_residues
MDDTTPPETPAVDDLLQRIAGAYDTLPRQLKRIASYIDEHRSSVMMDRTSDIAQRCGVHPSAVVRFAQRFGFSGFSDLQA
VFKDAYTGQNPTVQSYQQRIRSLIDGEAGPMTGGAVARQFIDASRAGLDELAAGLDDDQFDAAVTMLERAENIYVVGVRR
SFPVASYIVYALQHTAKRVHLVSGLGGMYREQIRSVKKGDVVIAISFAPYGKETQYCLRAARHNHAQTLVVTDSRLSPLA
RDASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDIGGYDD

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=234, Percent_Identity=24.3589743589744, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32230; Mature: 32230

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDTTPPETPAVDDLLQRIAGAYDTLPRQLKRIASYIDEHRSSVMMDRTSDIAQRCGVHP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SAVVRFAQRFGFSGFSDLQAVFKDAYTGQNPTVQSYQQRIRSLIDGEAGPMTGGAVARQF
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IDASRAGLDELAAGLDDDQFDAAVTMLERAENIYVVGVRRSFPVASYIVYALQHTAKRVH
HHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LVSGLGGMYREQIRSVKKGDVVIAISFAPYGKETQYCLRAARHNHAQTLVVTDSRLSPLA
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHH
RDASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDIGGYDD
HCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
>Mature Secondary Structure
MDDTTPPETPAVDDLLQRIAGAYDTLPRQLKRIASYIDEHRSSVMMDRTSDIAQRCGVHP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SAVVRFAQRFGFSGFSDLQAVFKDAYTGQNPTVQSYQQRIRSLIDGEAGPMTGGAVARQF
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IDASRAGLDELAAGLDDDQFDAAVTMLERAENIYVVGVRRSFPVASYIVYALQHTAKRVH
HHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LVSGLGGMYREQIRSVKKGDVVIAISFAPYGKETQYCLRAARHNHAQTLVVTDSRLSPLA
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHH
RDASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDIGGYDD
HCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA