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The map label for this gene is ychM [C]

Identifier: 53719491

GI number: 53719491

Start: 2236553

End: 2238265

Strand: Reverse

Name: ychM [C]

Synonym: BPSL1878

Alternate gene names: 53719491

Gene position: 2238265-2236553 (Counterclockwise)

Preceding gene: 53719492

Following gene: 53719488

Centisome position: 54.93

GC content: 70.69

Gene sequence:

>1713_bases
ATGGATCTCCGCTCGAAGCACATCGACGCGCCGCCGCAGCATGCCGCGCATTTCGCGCCGCTCGACGAGCCGCCCGCGCC
GCGCGCCCGCCGCACCGCGCTCGACGCGCTCGCCGGGCTGTCGATCGCGGGCCTTCTGATACCCGAGGCGGTCGCCTACG
CGGGGCTCGCGAACCTGCCGCCGCAGGCGGGGCTCATCGCGCTCGTCGTGGGGCTCGTCGTCTACGCGATCGCGGGCAGC
AGCCGCTTCGCGATCGTGTCGGCGACGTCGTCGTCGGCCGTCGTGCTCGCGGCGACCGTGATGTCCGAGGCCGGACCGGG
CGCCGCCGCGCAGTTGATGCTCGCCGCGGCGCTCGTCGCGACGACGGGCATCCTGTTCATCCTCGCGGGCGCCGCGCGTC
TCGGCGGCATGTCGGATTTCATCGCGCGGCCGGTGCTGCGCGGCTTCACGTTCGGCCTTGCACTCACGATCGTGATCAAG
CAGTTGCCGAAGATGCTCGACGTGCCGATCCATCACGGCGATACGCTGCGCGTCGCGCTCGACCTGCTGCTCGGCATTGC
GGGCTGCAATGTCCGCAGCGCGGGGCTCGGCGCGACCGCGCTGGCGATCCTGTTCGCGCTCGGCAGGCGCACGCGCGTGC
CGGCGACGCTCGTCGTGATCGTGCTCGGCATCGCGGCCGGCTACTGGATCGATTGGCATCGCTACGGCATCGCCGTCGTC
GGTACGATCGATCTGCAGAATCTCGCGTTCGGCATGCCGGTGCTCGGCCGCTCCGGCTGGATGCAGACGGCCGAGTTCGG
CTTCGCGCTGATGCTGATCCTGTACGCGGAATCGTACGGGTCGATTCGCAACTTCGCGCTCAAGCACGGCGATACGGTCT
CGCCGAACCGCGATCTCGTCGCGCTCGGCTGCGCGAACCTCGTATCGGGGCTGCTGCATGGGATGCCCGTCGGCGCGGGC
TATTCGGCGACCTCGGCGAACGAGGCGGCGGGCGCGCAAACGCGTATGGCGGGCCTGTTCGCGGCCGCCGTGATCGCGCT
GATCGCCTGGCTGCTGCTGCCGCAGCTCGCGCGCATTCCCGAGCCCGTGCTCGCGGCGATCGTGATCTTCGCGGTCAGCC
ATTCGCTGCATCCGGAGGTGTTCCGGCCGTACTGGACCTGGCATCGGGACCGGATCGTCGTGATCGCCGCGCTCGCGGCG
GTGATCGTGCTCGGCGTGCTGCACGGCCTGCTCGCCGCGATCGGCGTGAGCCTGCTGCTCACGTTGCGGCAATTGTCCGA
GCCGAACGTGAGCGTGCTGGGCCGGCTGCGCGGGAGCCACGATTTCGTCGACGTATCGATGCACGAGGATGCGAAGCCGA
TCCCCGGCGTGCTGATCGTGCGGCCGGAAGCCCAGCTCTTCTTCGCGAACGCGGAGCGCGTGCTGACCATGGCGAGGCGC
CTCGCGCGCGACGCGCAGCCGCCCGTGCACACGGTGATGCTGAGTCTCGAGGAATCGCCCGACGTCGACGGCACGACGAT
CGAGGCGCTGAAGACGTTCGGCGCCGAATGCGATGCGCGCGGCTGGCGCCTCGCGCTCGTGCGCCTGAAGCCGAACGTGC
TGCGCGTGCTGCAACGCGCGGCGGACGGCGGGCTGCGCGCGGATGCGCTGTCGGAGCTGAGCGTCGACGAGAGCCTGCAA
TCGCTGACGGCGGGCGAGTTGCCGCGCGCGTGA

Upstream 100 bases:

>100_bases
CAGGAGGCGCGCTATCTGCCGGGCTGGTCCGGCGTGATCGCGGCGCCGCGCTGAGCGCCGCGCCTTCGTTCGCACGACGG
GCAACACCCACGGAACGCGC

Downstream 100 bases:

>100_bases
CGGACGCGGATGCGGGCGCGATGCGTCGATGCGTGACGCTCGATGTCCGATGTCCGATGTCCGATGTCCGATGTCCGATG
TCCGATGTCCGATGTCCGAT

Product: putative sulfate transporter membrane protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QLPKMLDVPIHHGDTLRVALDLLLGIAGCNVRSAGLGATALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRAADGGLRADALSELSVDESLQ
SLTAGELPRA

Sequences:

>Translated_570_residues
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QLPKMLDVPIHHGDTLRVALDLLLGIAGCNVRSAGLGATALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRAADGGLRADALSELSVDESLQ
SLTAGELPRA
>Mature_570_residues
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QLPKMLDVPIHHGDTLRVALDLLLGIAGCNVRSAGLGATALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRAADGGLRADALSELSVDESLQ
SLTAGELPRA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI39752683, Length=491, Percent_Identity=25.050916496945, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI45827800, Length=491, Percent_Identity=25.050916496945, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI94721255, Length=460, Percent_Identity=28.0434782608696, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI94721253, Length=460, Percent_Identity=28.0434782608696, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI94721259, Length=460, Percent_Identity=28.0434782608696, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI94721257, Length=460, Percent_Identity=28.0434782608696, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI269784651, Length=488, Percent_Identity=24.5901639344262, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI47131207, Length=492, Percent_Identity=27.6422764227642, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI20336272, Length=492, Percent_Identity=27.6422764227642, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI217272867, Length=482, Percent_Identity=23.4439834024896, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI16418413, Length=482, Percent_Identity=23.4439834024896, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI4557535, Length=487, Percent_Identity=23.6139630390144, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI45827802, Length=448, Percent_Identity=24.3303571428571, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI4505697, Length=490, Percent_Identity=24.4897959183673, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI100913030, Length=490, Percent_Identity=22.8571428571429, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI262206105, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206075, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206069, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262206063, Length=270, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI20336282, Length=508, Percent_Identity=22.244094488189, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI16306483, Length=508, Percent_Identity=22.244094488189, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI16418457, Length=548, Percent_Identity=21.7153284671533, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI301601599, Length=548, Percent_Identity=21.7153284671533, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081859, Length=205, Percent_Identity=32.6829268292683, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17551690, Length=533, Percent_Identity=25.703564727955, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17566848, Length=572, Percent_Identity=25.1748251748252, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI86565215, Length=495, Percent_Identity=24.040404040404, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193203292, Length=483, Percent_Identity=22.7743271221532, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562578, Length=534, Percent_Identity=22.6591760299625, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI86564196, Length=474, Percent_Identity=21.3080168776371, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI86564876, Length=521, Percent_Identity=20.5374280230326, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86565213, Length=263, Percent_Identity=25.4752851711027, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325260, Length=497, Percent_Identity=24.9496981891348, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24651449, Length=561, Percent_Identity=24.777183600713, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24649801, Length=564, Percent_Identity=24.645390070922, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21358229, Length=573, Percent_Identity=24.78184991274, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24666186, Length=519, Percent_Identity=23.8921001926782, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922482, Length=594, Percent_Identity=22.7272727272727, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647160, Length=493, Percent_Identity=23.1237322515213, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355087, Length=493, Percent_Identity=23.3265720081136, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21358633, Length=429, Percent_Identity=24.9417249417249, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI85815873, Length=470, Percent_Identity=22.5531914893617, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24663084, Length=560, Percent_Identity=23.2142857142857, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357695, Length=560, Percent_Identity=23.2142857142857, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 59883; Mature: 59883

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALVVGLVVYAIAGSSRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
TTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIKQLPKMLDVPIHHGDTLRVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DLLLGIAGCNVRSAGLGATALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEHHHCCEEEE
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLV
EEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAAVIVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
HHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRA
HHHCCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHH
ADGGLRADALSELSVDESLQSLTAGELPRA
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLRSKHIDAPPQHAAHFAPLDEPPAPRARRTALDALAGLSIAGLLIPEAVAYAGLANLP
CCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQAGLIALVVGLVVYAIAGSSRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHH
TTGILFILAGAARLGGMSDFIARPVLRGFTFGLALTIVIKQLPKMLDVPIHHGDTLRVAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DLLLGIAGCNVRSAGLGATALAILFALGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEHHHCCEEEE
GTIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTVSPNRDLV
EEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRMAGLFAAAVIALIAWLLLPQLARIP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVLAAIVIFAVSHSLHPEVFRPYWTWHRDRIVVIAALAAVIVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRQLSEPNVSVLGRLRGSHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
HHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLALVRLKPNVLRVLQRA
HHHCCCCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHH
ADGGLRADALSELSVDESLQSLTAGELPRA
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]