BacMap

Definition	Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence.
Accession	NC_006350
Length	4,074,542

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The map label for this gene is yusZ [H]

Identifier: 53719360

GI number: 53719360

Start: 2058928

End: 2059722

Strand: Reverse

Name: yusZ [H]

Synonym: BPSL1746

Alternate gene names: 53719360

Gene position: 2059722-2058928 (Counterclockwise)

Preceding gene: 53719361

Following gene: 53719350

Centisome position: 50.55

GC content: 72.2

Gene sequence:

>795_bases
ATGACGGGTAAACGCATTCTGGTGACGGGCGCGGGCTCGGGTTTCGGCCGCGAGGTCGCGCTGCGGCTCGCCGCGAAGGG
CCATTGCGTGATCGCGGGGGTGCAGATCGCCCCGCAGATCACCGAGCTGAGCGCCGAGGCCGCGCGGCGCGGGCTCGCGC
TCGACGCGGTGAAGCTCGACGTGACGTGCGCGCGCGAGCGCGCGCAGGCCGCGCGCTGGGACGTGGACGTGCTGTTGAAC
AACGCGGGCGCGGGCGAGGCGGGCGCGCTCGTCGATCTGCCCGTCGACATCGTTCGCGAGCTGTTCGAGACCAACGTGTT
CGGCCCGCTCGAGCTCACGCAGCAGGTCGCGCGCGGGATGATCGCGCGCGGGCGGGGCAGGATCGTGTTCGTGTCGTCGA
TCGCGGGGCTCATCACGGGCGCGTACACGGGCGCGTACTGCGCGTCGAAGCACGCGCTCGAGGCGATCGCCGAGGCGATG
CACCTGGAGCTCGCCGCGCATGGCGTCCAGATCGCGGTCGTCAACCCGGGGCCGTACCGCACGGGCTTCAACGACCGGAT
GATGGAGACGCCGCGCCGCTGGCTCGACCCGGCGCGCGACGCGGCGACGCCCGAGACGCTCACGTTCCCGCTCGAGCAGT
TCGATCCGCAGGAGATGATCGAGAAGATGGTCGACGTGACCGAGGCCGACGGCGGGCTGTTCCGCAATCTGCTGCCCGCC
GCCGCCGAGCAGATCGTGCGCGACGAGCAGGCGCACGCGTGGACGCGCCGTCAGAACGAGCGGCGCGGCGCGTGA

Upstream 100 bases:

>100_bases
TCGGCGTGTCGGGCGGCACGGTCGACGACGACGCGGCGATCGCGCAGGTGTGCGTCGACGCTTTCATCACTCTTCTGAAC
GCAGCACAAGGAGCAAGGAC

Downstream 100 bases:

>100_bases
GCAGCCGGCGCGCGGCGATCGCGACGAGCCGCGCGGCCCGCGCCGAGGCCGAGTGCGCCGCGCCGTTGGTCGCTACCGAC
GCCGAAGCGGCGTGGCCGCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTGKRILVTGAGSGFGREVALRLAAKGHCVIAGVQIAPQITELSAEAARRGLALDAVKLDVTCARERAQAARWDVDVLLN
NAGAGEAGALVDLPVDIVRELFETNVFGPLELTQQVARGMIARGRGRIVFVSSIAGLITGAYTGAYCASKHALEAIAEAM
HLELAAHGVQIAVVNPGPYRTGFNDRMMETPRRWLDPARDAATPETLTFPLEQFDPQEMIEKMVDVTEADGGLFRNLLPA
AAEQIVRDEQAHAWTRRQNERRGA

Sequences:

>Translated_264_residues
MTGKRILVTGAGSGFGREVALRLAAKGHCVIAGVQIAPQITELSAEAARRGLALDAVKLDVTCARERAQAARWDVDVLLN
NAGAGEAGALVDLPVDIVRELFETNVFGPLELTQQVARGMIARGRGRIVFVSSIAGLITGAYTGAYCASKHALEAIAEAM
HLELAAHGVQIAVVNPGPYRTGFNDRMMETPRRWLDPARDAATPETLTFPLEQFDPQEMIEKMVDVTEADGGLFRNLLPA
AAEQIVRDEQAHAWTRRQNERRGA
>Mature_263_residues
TGKRILVTGAGSGFGREVALRLAAKGHCVIAGVQIAPQITELSAEAARRGLALDAVKLDVTCARERAQAARWDVDVLLNN
AGAGEAGALVDLPVDIVRELFETNVFGPLELTQQVARGMIARGRGRIVFVSSIAGLITGAYTGAYCASKHALEAIAEAMH
LELAAHGVQIAVVNPGPYRTGFNDRMMETPRRWLDPARDAATPETLTFPLEQFDPQEMIEKMVDVTEADGGLFRNLLPAA
AEQIVRDEQAHAWTRRQNERRGA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=246, Percent_Identity=31.3008130081301, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI223718074, Length=203, Percent_Identity=32.512315270936, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=33.8541666666667, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=33.8383838383838, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI19743808, Length=228, Percent_Identity=30.7017543859649, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI150247226, Length=250, Percent_Identity=29.6, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI40548397, Length=234, Percent_Identity=29.9145299145299, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI214010158, Length=234, Percent_Identity=29.9145299145299, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI214010156, Length=234, Percent_Identity=29.9145299145299, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI22758144, Length=234, Percent_Identity=29.9145299145299, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI22507405, Length=190, Percent_Identity=32.1052631578947, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=194, Percent_Identity=32.9896907216495, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI50726952, Length=185, Percent_Identity=32.4324324324324, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI119392083, Length=184, Percent_Identity=35.3260869565217, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI44680136, Length=190, Percent_Identity=28.4210526315789, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI44680133, Length=190, Percent_Identity=28.4210526315789, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI17738292, Length=190, Percent_Identity=28.4210526315789, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI32483357, Length=214, Percent_Identity=28.0373831775701, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503817, Length=219, Percent_Identity=27.8538812785388, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI210032110, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=212, Percent_Identity=28.7735849056604, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=33.5051546391753, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082100, Length=235, Percent_Identity=30.2127659574468, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788459, Length=186, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082160, Length=191, Percent_Identity=27.7486910994764, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=31.3186813186813, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790717, Length=216, Percent_Identity=27.3148148148148, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI2367365, Length=188, Percent_Identity=30.8510638297872, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=181, Percent_Identity=34.8066298342541, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787905, Length=219, Percent_Identity=28.310502283105, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789208, Length=222, Percent_Identity=27.9279279279279, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=31.1827956989247, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=193, Percent_Identity=33.6787564766839, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71997402, Length=194, Percent_Identity=31.4432989690722, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17507613, Length=278, Percent_Identity=26.6187050359712, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32563809, Length=275, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=218, Percent_Identity=29.3577981651376, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=281, Percent_Identity=27.4021352313167, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=198, Percent_Identity=30.8080808080808, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=195, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=28.4210526315789, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193210355, Length=190, Percent_Identity=30, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=277, Percent_Identity=26.3537906137184, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=31.0344827586207, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=203, Percent_Identity=30.5418719211823, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=233, Percent_Identity=28.3261802575107, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=240, Percent_Identity=27.5, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=199, Percent_Identity=30.6532663316583, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=193, Percent_Identity=28.4974093264249, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=28.2722513089005, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=24.5487364620939, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=177, Percent_Identity=29.9435028248588, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=29.7979797979798, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=32.48730964467, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=30.4123711340206, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364892, Length=268, Percent_Identity=27.6119402985075, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641232, Length=211, Percent_Identity=31.7535545023697, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644339, Length=209, Percent_Identity=29.1866028708134, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=179, Percent_Identity=32.4022346368715, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=32.7586206896552, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI116007236, Length=187, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=29.6703296703297, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355319, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=32.6315789473684, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571387, Length=187, Percent_Identity=29.9465240641711, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24643142, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=32.6315789473684, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28477; Mature: 28346

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKRILVTGAGSGFGREVALRLAAKGHCVIAGVQIAPQITELSAEAARRGLALDAVKLD
CCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEHEEEH
VTCARERAQAARWDVDVLLNNAGAGEAGALVDLPVDIVRELFETNVFGPLELTQQVARGM
HHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHH
IARGRGRIVFVSSIAGLITGAYTGAYCASKHALEAIAEAMHLELAAHGVQIAVVNPGPYR
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TGFNDRMMETPRRWLDPARDAATPETLTFPLEQFDPQEMIEKMVDVTEADGGLFRNLLPA
CCCCHHHHHCCHHHCCCHHCCCCCCEEECCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHH
AAEQIVRDEQAHAWTRRQNERRGA
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGKRILVTGAGSGFGREVALRLAAKGHCVIAGVQIAPQITELSAEAARRGLALDAVKLD
CCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEHEEEH
VTCARERAQAARWDVDVLLNNAGAGEAGALVDLPVDIVRELFETNVFGPLELTQQVARGM
HHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHHHHHHHH
IARGRGRIVFVSSIAGLITGAYTGAYCASKHALEAIAEAMHLELAAHGVQIAVVNPGPYR
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TGFNDRMMETPRRWLDPARDAATPETLTFPLEQFDPQEMIEKMVDVTEADGGLFRNLLPA
CCCCHHHHHCCHHHCCCHHCCCCCCEEECCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHH
AAEQIVRDEQAHAWTRRQNERRGA
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]