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The map label for this gene is upp [H]

Identifier: 53718802

GI number: 53718802

Start: 1345220

End: 1345870

Strand: Reverse

Name: upp [H]

Synonym: BPSL1166

Alternate gene names: 53718802

Gene position: 1345870-1345220 (Counterclockwise)

Preceding gene: 53718821

Following gene: 53718801

Centisome position: 33.03

GC content: 66.67

Gene sequence:

>651_bases
ATGAAACAGGACAGCCGTTTTCCGAATCTCTTCATCCTCGACCATCCGCTGATCCAGCACAAACTCACGCACATGCGCGA
CAAGGACACGTCCACCCGGACGTTCCGCGAGCTGCTGCGCGAGATCACGCTGCTGATGGGCTACGAGATCACCCGCAACC
TGCCGATCACGACGAAGCGGGTCGAAACCCCGCTCGTGGAGATCGACGCGCCCGTGATCGCCGGCAAGAAGCTCGCCATC
GTGCCCGTGCTGCGCGCGGGCGTCGGGATGTCGGACGGCCTGCTCGAGCTGATTCCGTCGGCGCGCGTCGGCCACATCGG
CGTGTACCGCGCCGACGACCACCGCCCGGTGGAATACCTGGTGCGGCTGCCCGACCTCGAAGACCGGATCTTCATCCTGT
GCGACCCGATGGTCGCGACGGGCTATTCGGCCGCGCACGCAATCGACGTCCTCAAGCGCCGCGGCGTGCCGGGCGAGCGA
CTCATGTTCCTCGCGCTCGTCGCCGCGCCCGAAGGCGTGCAGGTGTTCCAGGACGCGCATCCGGACGTGAAGCTGTATGT
CGCGTCGCTCGATTCGCACCTCGACGACCACGCGTACATCGTCCCCGGCCTGGGCGACGCGGGCGACCGCCTGTTCGGCA
CGAAGAACTGA

Upstream 100 bases:

>100_bases
CGGATCGCGCGCGCCCCATCTTCGGTAAACTTGCGGCTGTTGCGCGCGCGGCCTGCCGCCCCGGCACGCCCGCCGTCCCA
GAATCCCTTGAGCCGCCTCC

Downstream 100 bases:

>100_bases
CGGCCGAAACCGGCGCGCGAAACCGGCGCGAGAAGCGCTTGCCCGCCGTGCCCGCGCGGGTTTACCCCCGCGCGCGGCGA
GCCGCGAACCATCCGGGCGC

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGER
LMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN

Sequences:

>Translated_216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGER
LMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
>Mature_216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGER
LMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=32.6732673267327, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI87082118, Length=208, Percent_Identity=48.5576923076923, Blast_Score=194, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=26.7942583732057, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=26.7942583732057, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321920, Length=211, Percent_Identity=36.4928909952607, Blast_Score=117, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45550449, Length=222, Percent_Identity=32.8828828828829, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573516, Length=222, Percent_Identity=32.8828828828829, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573514, Length=222, Percent_Identity=32.8828828828829, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573512, Length=222, Percent_Identity=32.8828828828829, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358379, Length=209, Percent_Identity=27.7511961722488, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005765 [H]

Pfam domain/function: NA

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 24075; Mature: 24075

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYL
HCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGERLMFLALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCC
PDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
CCEEEEEEEHHCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYL
HCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGERLMFLALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCC
PDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
CCEEEEEEEHHCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA