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The map label for this gene is cobD [H]

Identifier: 53718627

GI number: 53718627

Start: 1143221

End: 1144165

Strand: Reverse

Name: cobD [H]

Synonym: BPSL0985

Alternate gene names: 53718627

Gene position: 1144165-1143221 (Counterclockwise)

Preceding gene: 53718628

Following gene: 53718626

Centisome position: 28.08

GC content: 77.25

Gene sequence:

>945_bases
ATGCTGATGCTGTCGCTGCCCGCCGTCGCCTGCCTCGCGGTCGCCGGCTGCGTCGTCGACAAGCTCGTCGGCGAGCCGCG
CGCCGCGCATCCGCTCGTCGCGTTCGGCCGGCTCGCCGCGCGCCTAGAACGCGCGCTCAACACCGGACGGCGCGGCCGGC
TCGCGGGCCTCGCCGCGTGGCTCGCCGCCGTCGCGCCGCCCGTCGCGCTCGCCGCGTGGCTCGCCGCCGCGCTGCCATGG
CCGCTCGCCGCCGCGCTGCACGTCGCGCTGCTGTGGTTCGCGCTCGGCGCGCGCAGCCTCGCCGAGCACGTCGCGCCGAT
CGCCGCGGCGCTGCTGCGCCGCGATCTCGCGGCCGCGCGCGCGCTGACCGCGCGCATCGTGTCGCGCGACACGAGCGCCG
CCGACGAGGCCGCGCTGTCGCGCGCGGCGGTCGAATCGGCGCTCGAGAACGGCAACGACGCGATCTTCGGTGCGCTCTTC
TGGTTCGCGATCGCGGGCGGCCCGGGCGCGCTGCTGTTCCGGCTCGCGAACACGCTCGATGCGATGTGGGGCTACCGCAC
GCCGCGCTTTGCGCGCTTCGGCTGGGCGGCCGCGCGCATCGACGACGCGCTCAACTGGGCCCCCGCGCGCCTCACCGCGG
CAAGCTACGCGCTGCTCGGCGACACCGCGAACGCATGGCGCTGCTGGCGCGCGCAGGCGCGCCACTGGGACAGCCCGAAC
GCGGGCCCCGTGATGGCCGCGGGCGCGGGCAGCCTGAACGTCGTGATCGGCGGCCCCGCCGTCTATCACGGCGCAATCGA
GGACCGCCCCGTGCTCGGCGCGGGCGAGCCCGCGGCGCCCGTGCACGTCGCGGCCGCGCTGTCGCTCGTCGCCCGCACGA
TGATTCTCTGGCTCGCGCTGCTCGTCGCCGGCGCGGCGCTGTCGATCGCGACGCACCATGGCTGA

Upstream 100 bases:

>100_bases
CGCTCGGCCGCGTCAATCAGCGCATCGCGGCGCTCGCGACACGCGTGACGCTGTGCGTGGCCGGCCTGCCCGTCACGGTC
AAGGACGAGGGCGAACCGCG

Downstream 100 bases:

>100_bases
CGCGCCGATCACGCACGGCGGCAACCTGCACGAAGCCGCCCTTCGCTACGGCATCCCGCGCGACGCGTGGCTCGATCTGT
CGACGGGCATCAATCCGCAC

Product: cobalamin biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLMLSLPAVACLAVAGCVVDKLVGEPRAAHPLVAFGRLAARLERALNTGRRGRLAGLAAWLAAVAPPVALAAWLAAALPW
PLAAALHVALLWFALGARSLAEHVAPIAAALLRRDLAAARALTARIVSRDTSAADEAALSRAAVESALENGNDAIFGALF
WFAIAGGPGALLFRLANTLDAMWGYRTPRFARFGWAAARIDDALNWAPARLTAASYALLGDTANAWRCWRAQARHWDSPN
AGPVMAAGAGSLNVVIGGPAVYHGAIEDRPVLGAGEPAAPVHVAAALSLVARTMILWLALLVAGAALSIATHHG

Sequences:

>Translated_314_residues
MLMLSLPAVACLAVAGCVVDKLVGEPRAAHPLVAFGRLAARLERALNTGRRGRLAGLAAWLAAVAPPVALAAWLAAALPW
PLAAALHVALLWFALGARSLAEHVAPIAAALLRRDLAAARALTARIVSRDTSAADEAALSRAAVESALENGNDAIFGALF
WFAIAGGPGALLFRLANTLDAMWGYRTPRFARFGWAAARIDDALNWAPARLTAASYALLGDTANAWRCWRAQARHWDSPN
AGPVMAAGAGSLNVVIGGPAVYHGAIEDRPVLGAGEPAAPVHVAAALSLVARTMILWLALLVAGAALSIATHHG
>Mature_314_residues
MLMLSLPAVACLAVAGCVVDKLVGEPRAAHPLVAFGRLAARLERALNTGRRGRLAGLAAWLAAVAPPVALAAWLAAALPW
PLAAALHVALLWFALGARSLAEHVAPIAAALLRRDLAAARALTARIVSRDTSAADEAALSRAAVESALENGNDAIFGALF
WFAIAGGPGALLFRLANTLDAMWGYRTPRFARFGWAAARIDDALNWAPARLTAASYALLGDTANAWRCWRAQARHWDSPN
AGPVMAAGAGSLNVVIGGPAVYHGAIEDRPVLGAGEPAAPVHVAAALSLVARTMILWLALLVAGAALSIATHHG

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 32463; Mature: 32463

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLSLPAVACLAVAGCVVDKLVGEPRAAHPLVAFGRLAARLERALNTGRRGRLAGLAAW
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LAAVAPPVALAAWLAAALPWPLAAALHVALLWFALGARSLAEHVAPIAAALLRRDLAAAR
HHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTARIVSRDTSAADEAALSRAAVESALENGNDAIFGALFWFAIAGGPGALLFRLANTLD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
AMWGYRTPRFARFGWAAARIDDALNWAPARLTAASYALLGDTANAWRCWRAQARHWDSPN
HHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
AGPVMAAGAGSLNVVIGGPAVYHGAIEDRPVLGAGEPAAPVHVAAALSLVARTMILWLAL
CCCEEEECCCCEEEEECCCHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVAGAALSIATHHG
HHHHHHHHHHCCCC
>Mature Secondary Structure
MLMLSLPAVACLAVAGCVVDKLVGEPRAAHPLVAFGRLAARLERALNTGRRGRLAGLAAW
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LAAVAPPVALAAWLAAALPWPLAAALHVALLWFALGARSLAEHVAPIAAALLRRDLAAAR
HHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTARIVSRDTSAADEAALSRAAVESALENGNDAIFGALFWFAIAGGPGALLFRLANTLD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
AMWGYRTPRFARFGWAAARIDDALNWAPARLTAASYALLGDTANAWRCWRAQARHWDSPN
HHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
AGPVMAAGAGSLNVVIGGPAVYHGAIEDRPVLGAGEPAAPVHVAAALSLVARTMILWLAL
CCCEEEECCCCEEEEECCCHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LVAGAALSIATHHG
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA