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The map label for this gene is cobP [H]

Identifier: 53718628

GI number: 53718628

Start: 1144159

End: 1144716

Strand: Reverse

Name: cobP [H]

Synonym: BPSL0986

Alternate gene names: 53718628

Gene position: 1144716-1144159 (Counterclockwise)

Preceding gene: 53718632

Following gene: 53718627

Centisome position: 28.09

GC content: 73.48

Gene sequence:

>558_bases
ATGATTCCGCGCGACCTCACCTTCGTTCTCGGCGGCGCGCGCTCGGGCAAGAGCGCGCACGCCGAACGGCTCGCCGCCGC
AGGCGGACGGCCCGTCACCTATATCGCCACCGCCCGCGTCGCGGACGACGAATTCGCCGAGCGCATCGCGCATCATCGCG
CGCGCCGGCCGGCCGGCTGGGCGCTCGTCGAGGCGCCCGTCGAGCTCGCGCCCGCGCTCGCCCGGCTCGACGACGCGAAC
GCGTGCGTGCTCGTCGATTGCCTCACGCTGTGGCTCACGAACCTGCTCTGCCCGGCCGACGGCCCGGGCGTCGACGACGC
GCGCTGCGACGCTTACGTCGCCGAACTCGAAGCGGCGCTGCGCGCGAGCCGCGCGCGGGTGATCGTCGTCAGCAACGAGA
TCGGCTTCGGCGTCGTGCCGCTCGGCAGGCAGACGCGCCGCTTCGTCGATACGCTCGGCCGCGTCAATCAGCGCATCGCG
GCGCTCGCGACACGCGTGACGCTGTGCGTGGCCGGCCTGCCCGTCACGGTCAAGGACGAGGGCGAACCGCGATGCTGA

Upstream 100 bases:

>100_bases
TGGCGTTGGCGTTGGCAATCATCGTGAACGAATGGCGCGACGCGCGGCGCGCGGCAAATGGCGAAGGCCGCATTATCGCG
CGGCCCGTTACAATCACGCG

Downstream 100 bases:

>100_bases
TGCTGTCGCTGCCCGCCGTCGCCTGCCTCGCGGTCGCCGGCTGCGTCGTCGACAAGCTCGTCGGCGAGCCGCGCGCCGCG
CATCCGCTCGTCGCGTTCGG

Product: putative bifunctional cobalamin biosynthesis protein

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRPAGWALVEAPVELAPALARLDDAN
ACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFGVVPLGRQTRRFVDTLGRVNQRIA
ALATRVTLCVAGLPVTVKDEGEPRC

Sequences:

>Translated_185_residues
MIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRPAGWALVEAPVELAPALARLDDAN
ACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFGVVPLGRQTRRFVDTLGRVNQRIA
ALATRVTLCVAGLPVTVKDEGEPRC
>Mature_185_residues
MIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRPAGWALVEAPVELAPALARLDDAN
ACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFGVVPLGRQTRRFVDTLGRVNQRIA
ALATRVTLCVAGLPVTVKDEGEPRC

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=41.9889502762431, Blast_Score=123, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19717; Mature: 19717

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRPAGW
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCC
ALVEAPVELAPALARLDDANACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAAL
EEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
RASRARVIVVSNEIGFGVVPLGRQTRRFVDTLGRVNQRIAALATRVTLCVAGLPVTVKDE
HHCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
GEPRC
CCCCC
>Mature Secondary Structure
MIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRPAGW
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCC
ALVEAPVELAPALARLDDANACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAAL
EEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
RASRARVIVVSNEIGFGVVPLGRQTRRFVDTLGRVNQRIAALATRVTLCVAGLPVTVKDE
HHCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
GEPRC
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]