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The map label for this gene is cobC [H]

Identifier: 53718626

GI number: 53718626

Start: 1142176

End: 1143228

Strand: Reverse

Name: cobC [H]

Synonym: BPSL0984

Alternate gene names: 53718626

Gene position: 1143228-1142176 (Counterclockwise)

Preceding gene: 53718627

Following gene: 53718625

Centisome position: 28.06

GC content: 75.97

Gene sequence:

>1053_bases
ATGGCTGACGCGCCGATCACGCACGGCGGCAACCTGCACGAAGCCGCCCTTCGCTACGGCATCCCGCGCGACGCGTGGCT
CGATCTGTCGACGGGCATCAATCCGCACGGTTTTCCGGTGCCGCCCGTGCCCGCCGACGCGTGGCGCCGGCTGCCCGAGG
ACGACGGCGTGCTCGCCGCGCACGCGGCGCGCTACTACCGCGCGCCGGGCGCGGCGCACGTGCTGCCCGTCGCGGGCAGC
CAGGCGGCGATCCGTGCGCTGCCGGCGCTTTTCGCGCGCGGCACGGTCGGCGTCGCGCCGCTCGCATACAGCGAGTACGC
GCCCGCGTTCGCGCGCCACGGCCATTCGGGCGCGCCGCTCGACTGCGGCGCCGACACGCTGCCCGCCGCGCTCACGTACG
CGATCGTCGCCAATCCGAACAATCCGACCGCCGAACGCATCGATCGCACGCGGCTGCTGCGCTGGCACGCGCAACTCGTC
GCGCGCGGCGGCGCGCTGATCGTCGACGAGGCGTTCGCGGACGCCGAGAGCGCCGCGCACGCGTCGCTCGCCGCGGACAC
GCATCGCGACGGCCTCGTCGTATTGCGCTCGGTCGGCAAGTTCTTCGGCCTCGCGGGCGTGCGCGCGGGCTTCGCGCTCG
CCGCGCCCGCGCTGCTCGCGCGGCTGCGCGACGCGCTCGGCGCGTGGACCGTCAGCGGCCCGGCGCGCCACGCGGTGCTC
GCCGCGTTCGCGGACGCGGCGTGGCAGCACGCGATGCGCGAGCGGCTCGCGCACGACGGCGCGCGCCTTGCCGCGCTGCT
GCGCGCGCACGGCTTCGTCACGCACGCGACGCCGCTTTTCAGCTGGAGCGCCGATCCGCGCGCGCACGCGCTGCACGACG
CGCTCGCGGCGCGCGGAATCTGGACGCGCTACTTCGCGCACGCGCCGAGCGTGCGCATCGGGCTGCCCGCCGGCGACGAC
GACTGGCGGCGGCTCGAACGCACGCTCGCCGAGTGCGTGCCGACGCTAGCGGCCGCAGCCGCGCATCCTTCCGAATCGAC
CACACGGGATTGA

Upstream 100 bases:

>100_bases
CCCGTGCACGTCGCGGCCGCGCTGTCGCTCGTCGCCCGCACGATGATTCTCTGGCTCGCGCTGCTCGTCGCCGGCGCGGC
GCTGTCGATCGCGACGCACC

Downstream 100 bases:

>100_bases
CACCGATGCGCCCCGCCCTGCGCCGCGCCGCACGCATCGCACTCGCCGCCCTCTTCTGCGCGAGCGCATGCGCGCATGCG
CTCGCCGCCGCGCATGCGGA

Product: putative threonine-phosphate decarboxylase

Products: NA

Alternate protein names: L-threonine-O-3-phosphate decarboxylase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MADAPITHGGNLHEAALRYGIPRDAWLDLSTGINPHGFPVPPVPADAWRRLPEDDGVLAAHAARYYRAPGAAHVLPVAGS
QAAIRALPALFARGTVGVAPLAYSEYAPAFARHGHSGAPLDCGADTLPAALTYAIVANPNNPTAERIDRTRLLRWHAQLV
ARGGALIVDEAFADAESAAHASLAADTHRDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
AAFADAAWQHAMRERLAHDGARLAALLRAHGFVTHATPLFSWSADPRAHALHDALAARGIWTRYFAHAPSVRIGLPAGDD
DWRRLERTLAECVPTLAAAAAHPSESTTRD

Sequences:

>Translated_350_residues
MADAPITHGGNLHEAALRYGIPRDAWLDLSTGINPHGFPVPPVPADAWRRLPEDDGVLAAHAARYYRAPGAAHVLPVAGS
QAAIRALPALFARGTVGVAPLAYSEYAPAFARHGHSGAPLDCGADTLPAALTYAIVANPNNPTAERIDRTRLLRWHAQLV
ARGGALIVDEAFADAESAAHASLAADTHRDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
AAFADAAWQHAMRERLAHDGARLAALLRAHGFVTHATPLFSWSADPRAHALHDALAARGIWTRYFAHAPSVRIGLPAGDD
DWRRLERTLAECVPTLAAAAAHPSESTTRD
>Mature_349_residues
ADAPITHGGNLHEAALRYGIPRDAWLDLSTGINPHGFPVPPVPADAWRRLPEDDGVLAAHAARYYRAPGAAHVLPVAGSQ
AAIRALPALFARGTVGVAPLAYSEYAPAFARHGHSGAPLDCGADTLPAALTYAIVANPNNPTAERIDRTRLLRWHAQLVA
RGGALIVDEAFADAESAAHASLAADTHRDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVLA
AFADAAWQHAMRERLAHDGARLAALLRAHGFVTHATPLFSWSADPRAHALHDALAARGIWTRYFAHAPSVRIGLPAGDDD
WRRLERTLAECVPTLAAAAAHPSESTTRD

Specific function: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin [H]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005860
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =4.1.1.81 [H]

Molecular weight: Translated: 36925; Mature: 36794

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAPITHGGNLHEAALRYGIPRDAWLDLSTGINPHGFPVPPVPADAWRRLPEDDGVLAA
CCCCCCCCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHH
HAARYYRAPGAAHVLPVAGSQAAIRALPALFARGTVGVAPLAYSEYAPAFARHGHSGAPL
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHCCCCCCCC
DCGADTLPAALTYAIVANPNNPTAERIDRTRLLRWHAQLVARGGALIVDEAFADAESAAH
CCCCCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
ASLAADTHRDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AAFADAAWQHAMRERLAHDGARLAALLRAHGFVTHATPLFSWSADPRAHALHDALAARGI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHCCCHHEECCCCCHHHHHHHHHHHHHH
WTRYFAHAPSVRIGLPAGDDDWRRLERTLAECVPTLAAAAAHPSESTTRD
HHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADAPITHGGNLHEAALRYGIPRDAWLDLSTGINPHGFPVPPVPADAWRRLPEDDGVLAA
CCCCCCCCCCHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHH
HAARYYRAPGAAHVLPVAGSQAAIRALPALFARGTVGVAPLAYSEYAPAFARHGHSGAPL
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHCCCCCCCC
DCGADTLPAALTYAIVANPNNPTAERIDRTRLLRWHAQLVARGGALIVDEAFADAESAAH
CCCCCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
ASLAADTHRDGLVVLRSVGKFFGLAGVRAGFALAAPALLARLRDALGAWTVSGPARHAVL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AAFADAAWQHAMRERLAHDGARLAALLRAHGFVTHATPLFSWSADPRAHALHDALAARGI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHCCCHHEECCCCCHHHHHHHHHHHHHH
WTRYFAHAPSVRIGLPAGDDDWRRLERTLAECVPTLAAAAAHPSESTTRD
HHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]