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The map label for this gene is tctD [H]

Identifier: 53718414

GI number: 53718414

Start: 902391

End: 903134

Strand: Reverse

Name: tctD [H]

Synonym: BPSL0775

Alternate gene names: 53718414

Gene position: 903134-902391 (Counterclockwise)

Preceding gene: 53718425

Following gene: 53718413

Centisome position: 22.17

GC content: 70.03

Gene sequence:

>744_bases
ATGCGAATTCTCATCGCCGAAGACGACAGCATACTAGCGGACGGCCTCACCCGGTCACTCCGCCAATCGGGCTATGCCGT
CGATCACGTGAGGAACGGCGTCGAGGCCGACACGGCCCTGTCGATGCAGACTTTCGACCTGCTGATCCTCGATCTCGGCC
TGCCCAGAATGTCCGGCCTCGAGGTGCTGCGCCGCCTGCGCGCGCGCAACTCGAACCTGCCCGTGCTGATCCTGACGGCC
GCCGACAGCGTCGACGAGCGCGTGAAAGGGCTCGACCTGGGCGCCGACGACTACATGGCGAAGCCGTTCGCGCTCAACGA
GCTCGAGGCGCGCGTGCGCGCGCTGACGCGGCGCGGCGCGGGAGGCGGGCCGACCGTCGTGCGGCATGGCTCGCTGTCGT
TCGACCAGGTCGGCCGGATCGCCTATGCGAACGAACGCGTGCTCGAGCTGTCCGCGCGCGAGCTCGGGCTGCTCGAGGTG
CTGCTGCAGCGCATCGGCCGGCTGGTGTCGAAGGAGCAGCTCGTCGATCACCTGTGCGAATGGGGCGAGGAAGTCAGCAA
CAACGCGATCGAGGTCTACGTCCACCGGCTGCGCAAGAAGATCGAGCCGAGCGGCGTGCGGATCACGACCGTGCGCGGCC
TCGGCTACTGCCTCGAGAAAGCCGCGCCCGCGGGCGCGAGCGACGCGCCGAACGCCGCCGCGTCGCCGGCGGCCGAGGCC
GTCGCCGGCCAGCCGGTGCGCTAG

Upstream 100 bases:

>100_bases
CAGTGGTTTATGCAAGCCCGCGTTGCAGGCAGGCATCGCCCAATTTCGGAGACAGCCGCGCGCAGCGTCATTGCCGCCCA
GCGGCAATCGGTTGCGCATC

Downstream 100 bases:

>100_bases
CGCCGCCCACGCGCGAGCGGCCGATGGCCACGCCGGTTCGTCCCGCCCACGCCTCGCGCCGCGCGAGCGCCGCGGCGCCC
GATACGGATGCCGCGCGCGA

Product: response regulator transcription regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEADTALSMQTFDLLILDLGLPRMSGLEVLRRLRARNSNLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLSFDQVGRIAYANERVLELSARELGLLEV
LLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRITTVRGLGYCLEKAAPAGASDAPNAAASPAAEA
VAGQPVR

Sequences:

>Translated_247_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEADTALSMQTFDLLILDLGLPRMSGLEVLRRLRARNSNLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLSFDQVGRIAYANERVLELSARELGLLEV
LLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRITTVRGLGYCLEKAAPAGASDAPNAAASPAAEA
VAGQPVR
>Mature_247_residues
MRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEADTALSMQTFDLLILDLGLPRMSGLEVLRRLRARNSNLPVLILTA
ADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGAGGGPTVVRHGSLSFDQVGRIAYANERVLELSARELGLLEV
LLQRIGRLVSKEQLVDHLCEWGEEVSNNAIEVYVHRLRKKIEPSGVRITTVRGLGYCLEKAAPAGASDAPNAAASPAAEA
VAGQPVR

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=44.954128440367, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=42.6605504587156, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=39.1891891891892, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.2857142857143, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=37.10407239819, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=34.841628959276, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=34.6846846846847, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.4978165938865, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=33.0316742081448, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=31.3304721030043, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=32.1888412017167, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=41.7391304347826, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.7610619469027, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=29.6610169491525, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=33.5766423357664, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=27.6150627615063, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=35.0877192982456, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26740; Mature: 26740

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEADTALSMQTFDLLILDLGLPRMSGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EVLRRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGA
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
GGGPTVVRHGSLSFDQVGRIAYANERVLELSARELGLLEVLLQRIGRLVSKEQLVDHLCE
CCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEPSGVRITTVRGLGYCLEKAAPAGASDAPNAAASPAAEA
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
VAGQPVR
HCCCCCC
>Mature Secondary Structure
MRILIAEDDSILADGLTRSLRQSGYAVDHVRNGVEADTALSMQTFDLLILDLGLPRMSGL
CEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EVLRRLRARNSNLPVLILTAADSVDERVKGLDLGADDYMAKPFALNELEARVRALTRRGA
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
GGGPTVVRHGSLSFDQVGRIAYANERVLELSARELGLLEVLLQRIGRLVSKEQLVDHLCE
CCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGEEVSNNAIEVYVHRLRKKIEPSGVRITTVRGLGYCLEKAAPAGASDAPNAAASPAAEA
HHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
VAGQPVR
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]