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The map label for this gene is qseC [H]

Identifier: 53718413

GI number: 53718413

Start: 900811

End: 902367

Strand: Reverse

Name: qseC [H]

Synonym: BPSL0774

Alternate gene names: 53718413

Gene position: 902367-900811 (Counterclockwise)

Preceding gene: 53718414

Following gene: 53718412

Centisome position: 22.15

GC content: 70.52

Gene sequence:

>1557_bases
ATGGCCACGCCGGTTCGTCCCGCCCACGCCTCGCGCCGCGCGAGCGCCGCGGCGCCCGATACGGATGCCGCGCGCGACGC
GCGCTACGAGAACCCGTTCGCGCCGCCGGACGAAGCCGACGCCGCCGAAGGCACCCGCCCGCGCTCGCTGTTCGGCGAGA
TTCTCGACTGGATGCTCGCGCCGCTCCTTCTGCTGTGGCCGATGAGCATCGCCGTCACCTACCTCGTCGCGAAAACGATC
GCGAACGGCCCGTTCGACCGCGCGCTCGAGACCGACGCTTACGTGCTCGCCCGGCAGATCACGCCCATCAACGGCGTCGC
CGAACTGAGACTGCCGCAGGCGACGCTCGACTTCCTGCGCGCCGACAACGTCGATAGCCTCTATTTCCAGGTGCTCGGCA
CGCGCGGCGAACTCGTCGCGGGCGAAGCCGACCTGCCGCTGCCGCGCGACGACGACCGGCCGGCGCCGGGCGTCGTCGTG
TTCCGCGACGATCTGCTGCGCGGCAACGACGTGCGCGTCGCATACACGAGCGTCGCGCTGCAGGGCGCGACGGGCTCGCA
GCCCGTGCTCGTGCAGGTCGGCGAGACGCTGGACAAGCGCAACGCGCTCGCCAACGACATCATCAAGGGCGTGATCCTGC
CGCAATTCGTGATCCTGCCGCTCGCGATCCTGCTCGTCTGGTTCGGGCTGTCGCGCGGGCTCGCGCCGCTCACCGCGCTG
CAGGCGCACATTCGCGGCCGGCGCCCGGACGATCTGTCGCCCGTCGAGGCGCGGCGCGCGCCGCCAGAGATCGAGCCGCT
CGTCACGTCGTTCAACGATCTGCTCGCGCGTCTCGAACAGAACATCACGCTGCAAAAGCGCTTCATCGCCGACGCCGCGC
ACCAGATGAAAACGCCGCTCGCCGGCCTGCGCACGCAGGCGGAATTCGCGCTGCGCCATGAAGTGAACGCCGACGTCGCA
CGCTCGCTCGAACAGATCGCGACGAGCTCCGAGCAGGCGGCGCGACTCGTCACGCAACTGCTCGCGCTCGCGCGCGCGGA
AAATCGCGCGACGGGGCTCACGTTCGAGCCCGTCGAGATCGCGTCGCTCGCGCGGCAGGCGGTGCGCGACTGGGTGCAGG
CCGCGCTCGCGAAGCAGATGGATCTCGGCTACGAAGGCCCGGACACCGACGCCCCGCTTCGCATCGACGGACAGCCGGTG
ATGCTGCGCGAGATGCTCGGCAACCTGATCGACAACGCGATTCGCTACACGCCGGCGGGCGGCCGCATCACCGTGCGCGT
GCACGCCGAGCGCGCGGCGGGCGCCGTGCATCTCGAAGTCGAGGACACGGGCCCCGGCATTCCGCCGAACGAGCGCGAGC
GGGTGGTCGAGCGCTTCTACCGGATCCTCGGCCGCGAAGGCGATGGCAGCGGGCTCGGCCTTGCGATCGTCCGCGAGATC
GTCGCGCAACACGGCGGCACGCTGACGATCGACGACAACGTCTATCAGACGTCGCCGCGCCTCGCGGGCACGCTCGTGCG
CGTGAGCATCGGCTTACGGCAAGAGGCCCCGGAATAA

Upstream 100 bases:

>100_bases
CCGCGGGCGCGAGCGACGCGCCGAACGCCGCCGCGTCGCCGGCGGCCGAGGCCGTCGCCGGCCAGCCGGTGCGCTAGCGC
CGCCCACGCGCGAGCGGCCG

Downstream 100 bases:

>100_bases
CCCTAAGCGCAGCCGCCGCCCGCCCCTCGGCGGGCCCACAATACATGGAATTAACCGACGATCCCCAACAAATAAAAGAA
GAAGGCCGACATATCCACTG

Product: two-component sensor kinase transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MATPVRPAHASRRASAAAPDTDAARDARYENPFAPPDEADAAEGTRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTI
ANGPFDRALETDAYVLARQITPINGVAELRLPQATLDFLRADNVDSLYFQVLGTRGELVAGEADLPLPRDDDRPAPGVVV
FRDDLLRGNDVRVAYTSVALQGATGSQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLTAL
QAHIRGRRPDDLSPVEARRAPPEIEPLVTSFNDLLARLEQNITLQKRFIADAAHQMKTPLAGLRTQAEFALRHEVNADVA
RSLEQIATSSEQAARLVTQLLALARAENRATGLTFEPVEIASLARQAVRDWVQAALAKQMDLGYEGPDTDAPLRIDGQPV
MLREMLGNLIDNAIRYTPAGGRITVRVHAERAAGAVHLEVEDTGPGIPPNERERVVERFYRILGREGDGSGLGLAIVREI
VAQHGGTLTIDDNVYQTSPRLAGTLVRVSIGLRQEAPE

Sequences:

>Translated_518_residues
MATPVRPAHASRRASAAAPDTDAARDARYENPFAPPDEADAAEGTRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTI
ANGPFDRALETDAYVLARQITPINGVAELRLPQATLDFLRADNVDSLYFQVLGTRGELVAGEADLPLPRDDDRPAPGVVV
FRDDLLRGNDVRVAYTSVALQGATGSQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLTAL
QAHIRGRRPDDLSPVEARRAPPEIEPLVTSFNDLLARLEQNITLQKRFIADAAHQMKTPLAGLRTQAEFALRHEVNADVA
RSLEQIATSSEQAARLVTQLLALARAENRATGLTFEPVEIASLARQAVRDWVQAALAKQMDLGYEGPDTDAPLRIDGQPV
MLREMLGNLIDNAIRYTPAGGRITVRVHAERAAGAVHLEVEDTGPGIPPNERERVVERFYRILGREGDGSGLGLAIVREI
VAQHGGTLTIDDNVYQTSPRLAGTLVRVSIGLRQEAPE
>Mature_517_residues
ATPVRPAHASRRASAAAPDTDAARDARYENPFAPPDEADAAEGTRPRSLFGEILDWMLAPLLLLWPMSIAVTYLVAKTIA
NGPFDRALETDAYVLARQITPINGVAELRLPQATLDFLRADNVDSLYFQVLGTRGELVAGEADLPLPRDDDRPAPGVVVF
RDDLLRGNDVRVAYTSVALQGATGSQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLTALQ
AHIRGRRPDDLSPVEARRAPPEIEPLVTSFNDLLARLEQNITLQKRFIADAAHQMKTPLAGLRTQAEFALRHEVNADVAR
SLEQIATSSEQAARLVTQLLALARAENRATGLTFEPVEIASLARQAVRDWVQAALAKQMDLGYEGPDTDAPLRIDGQPVM
LREMLGNLIDNAIRYTPAGGRITVRVHAERAAGAVHLEVEDTGPGIPPNERERVVERFYRILGREGDGSGLGLAIVREIV
AQHGGTLTIDDNVYQTSPRLAGTLVRVSIGLRQEAPE

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=439, Percent_Identity=29.3849658314351, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786783, Length=305, Percent_Identity=33.7704918032787, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1790551, Length=289, Percent_Identity=32.5259515570934, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786600, Length=214, Percent_Identity=33.6448598130841, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=29.6943231441048, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1790861, Length=269, Percent_Identity=30.8550185873606, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=27.2108843537415, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=28.2157676348548, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=28.8888888888889, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=26.1467889908257, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=29.6, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787374, Length=315, Percent_Identity=27.9365079365079, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787894, Length=238, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.6018099547511, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=214, Percent_Identity=25.7009345794392, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=243, Percent_Identity=29.6296296296296, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790300, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=214, Percent_Identity=22.8971962616822, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=27.8969957081545, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=27.4900398406374, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56295; Mature: 56164

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPVRPAHASRRASAAAPDTDAARDARYENPFAPPDEADAAEGTRPRSLFGEILDWMLA
CCCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
PLLLLWPMSIAVTYLVAKTIANGPFDRALETDAYVLARQITPINGVAELRLPQATLDFLR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHH
ADNVDSLYFQVLGTRGELVAGEADLPLPRDDDRPAPGVVVFRDDLLRGNDVRVAYTSVAL
CCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEE
QGATGSQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLTAL
ECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QAHIRGRRPDDLSPVEARRAPPEIEPLVTSFNDLLARLEQNITLQKRFIADAAHQMKTPL
HHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCH
AGLRTQAEFALRHEVNADVARSLEQIATSSEQAARLVTQLLALARAENRATGLTFEPVEI
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHH
ASLARQAVRDWVQAALAKQMDLGYEGPDTDAPLRIDGQPVMLREMLGNLIDNAIRYTPAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHEECCCC
GRITVRVHAERAAGAVHLEVEDTGPGIPPNERERVVERFYRILGREGDGSGLGLAIVREI
CEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VAQHGGTLTIDDNVYQTSPRLAGTLVRVSIGLRQEAPE
HHHCCCEEEECCCCEECCCHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure 
ATPVRPAHASRRASAAAPDTDAARDARYENPFAPPDEADAAEGTRPRSLFGEILDWMLA
CCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
PLLLLWPMSIAVTYLVAKTIANGPFDRALETDAYVLARQITPINGVAELRLPQATLDFLR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHH
ADNVDSLYFQVLGTRGELVAGEADLPLPRDDDRPAPGVVVFRDDLLRGNDVRVAYTSVAL
CCCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEE
QGATGSQPVLVQVGETLDKRNALANDIIKGVILPQFVILPLAILLVWFGLSRGLAPLTAL
ECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QAHIRGRRPDDLSPVEARRAPPEIEPLVTSFNDLLARLEQNITLQKRFIADAAHQMKTPL
HHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCH
AGLRTQAEFALRHEVNADVARSLEQIATSSEQAARLVTQLLALARAENRATGLTFEPVEI
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHH
ASLARQAVRDWVQAALAKQMDLGYEGPDTDAPLRIDGQPVMLREMLGNLIDNAIRYTPAG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHEECCCC
GRITVRVHAERAAGAVHLEVEDTGPGIPPNERERVVERFYRILGREGDGSGLGLAIVREI
CEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VAQHGGTLTIDDNVYQTSPRLAGTLVRVSIGLRQEAPE
HHHCCCEEEECCCCEECCCHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]