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The map label for this gene is dgoD1 [H]

Identifier: 53718342

GI number: 53718342

Start: 797270

End: 798418

Strand: Reverse

Name: dgoD1 [H]

Synonym: BPSL0699

Alternate gene names: 53718342

Gene position: 798418-797270 (Counterclockwise)

Preceding gene: 53718344

Following gene: 53718340

Centisome position: 19.6

GC content: 67.19

Gene sequence:

>1149_bases
ATGAAAATCACCCGCCTCGAAACCTTCGTCGTGCCGCCTCGATGGCTGTTCCTGAAGATCGAGACCGACGCGGGCATCGT
CGGCTGGGGCGAGCCGATCGTCGAAGGCCGCGCGCATACGGTCGAGGCGGCCGTGCACGAGCTCGCCGACTACCTCGTCG
GCCAGGATCCGCTTCGCATCGAGGACCACTGGCAGGTGATGTACCGCGCGGGCTTCTACCGCGGCGGGCCGATCACGATG
AGCGCGATCGCGGGCATCGACCAGGCGCTCTGGGACATCAAGGGCAAGCATCACGGCGCGCCCGTGCATGCGCTCCTCGG
CGGCCCGGTGCGCGAGCGGATCAAGGTGTATTCGTGGATCGGCGGCGATCGGCCGAGCGACGTCGCGAACAACGCGCGCG
CGGTCGTCGAACGCGGCTTCCAGGCGGTGAAGATGAACGGCTCGGAAGAGCTGCAGATCGTCGACACCTTCGACAAGGTC
GACAAGGTGATCGCGAACGTCGCGGCGGTGCGCGACGCGGTGGGCCCGTACGTCGGCATCGGCGTCGATTTCCACGGCCG
CGTGCACAAGCCGATGGCGAAGGTACTCGCCAGGGAGCTCGATCCGTACAAGCTGATGTTCATCGAGGAGCCCGTGCTGT
CGGAGAACGCCGAGGCGCTGCGCGACATCGCGAACCAGACGAGCACGCCGATCGCGCTCGGCGAGCGGCTCTACTCGCGC
TGGGATTTCAAGCGCATTCTCGAAGGCGGCTACGTCGACATCGTGCAGCCCGACGCGTCGCACGCGGGCGGGATCACCGA
GTGCCGGAAGATCGCGACGCTCGCGGAAAGCTACGACGTCGCGCTCGCGCTGCACTGCCCGCTCGGGCCGATCGCGCTCG
CCGCGTGCCTGCAGCTCGACGCGGTCAGCTACAACGCGTTCATTCAGGAGCAGAGCCTCGGCATTCACTACAACCAGGGC
AGCGATCTGCTCGACTATCTGCGCAACCCGGACGTGTTCCGCTACGCGGACGGCTTCGTCGCGATTCCGCAGGGGCCCGG
GCTCGGCATCGACGTCGACGAGGACAAGGTGTGCGAGATGGCGAAAACCGGGCACCGCTGGCGTAATCCGGTATGGCGGC
ACGCGGACGGCAGCGTCGCCGAGTGGTGA

Upstream 100 bases:

>100_bases
TCACTATGTGCACAACGGCGCGATCGATACTACTTTCGCGCGACGCCGCTGTACGATTCACGCGTGATTCAAGCAGACCG
ACAGCCAGGAGACACCCGTC

Downstream 100 bases:

>100_bases
CGCGCGCAGCCGTCGCGCGGCTGGTGGGGTGAGTGGTTCAGCGGTTCGGCGGTTCAGCGGTTCAGCGGTTCAGCGGTTCA
GCGGTTCAGCGGTTCAGCGG

Product: galactonate dehydratase

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKITRLETFVVPPRWLFLKIETDAGIVGWGEPIVEGRAHTVEAAVHELADYLVGQDPLRIEDHWQVMYRAGFYRGGPITM
SAIAGIDQALWDIKGKHHGAPVHALLGGPVRERIKVYSWIGGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKV
DKVIANVAAVRDAVGPYVGIGVDFHGRVHKPMAKVLARELDPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSR
WDFKRILEGGYVDIVQPDASHAGGITECRKIATLAESYDVALALHCPLGPIALAACLQLDAVSYNAFIQEQSLGIHYNQG
SDLLDYLRNPDVFRYADGFVAIPQGPGLGIDVDEDKVCEMAKTGHRWRNPVWRHADGSVAEW

Sequences:

>Translated_382_residues
MKITRLETFVVPPRWLFLKIETDAGIVGWGEPIVEGRAHTVEAAVHELADYLVGQDPLRIEDHWQVMYRAGFYRGGPITM
SAIAGIDQALWDIKGKHHGAPVHALLGGPVRERIKVYSWIGGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKV
DKVIANVAAVRDAVGPYVGIGVDFHGRVHKPMAKVLARELDPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSR
WDFKRILEGGYVDIVQPDASHAGGITECRKIATLAESYDVALALHCPLGPIALAACLQLDAVSYNAFIQEQSLGIHYNQG
SDLLDYLRNPDVFRYADGFVAIPQGPGLGIDVDEDKVCEMAKTGHRWRNPVWRHADGSVAEW
>Mature_382_residues
MKITRLETFVVPPRWLFLKIETDAGIVGWGEPIVEGRAHTVEAAVHELADYLVGQDPLRIEDHWQVMYRAGFYRGGPITM
SAIAGIDQALWDIKGKHHGAPVHALLGGPVRERIKVYSWIGGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKV
DKVIANVAAVRDAVGPYVGIGVDFHGRVHKPMAKVLARELDPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSR
WDFKRILEGGYVDIVQPDASHAGGITECRKIATLAESYDVALALHCPLGPIALAACLQLDAVSYNAFIQEQSLGIHYNQG
SDLLDYLRNPDVFRYADGFVAIPQGPGLGIDVDEDKVCEMAKTGHRWRNPVWRHADGSVAEW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=382, Percent_Identity=63.0890052356021, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1787864, Length=413, Percent_Identity=31.7191283292978, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI226510960, Length=220, Percent_Identity=32.7272727272727, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42223; Mature: 42223

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITRLETFVVPPRWLFLKIETDAGIVGWGEPIVEGRAHTVEAAVHELADYLVGQDPLRI
CCCEEEEEEEECCEEEEEEEECCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEE
EDHWQVMYRAGFYRGGPITMSAIAGIDQALWDIKGKHHGAPVHALLGGPVRERIKVYSWI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHC
GGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKVDKVIANVAAVRDAVGPYVGI
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEE
GVDFHGRVHKPMAKVLARELDPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSR
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHCCCHHHHHHHHHCCCCCHHHHHHHHHH
WDFKRILEGGYVDIVQPDASHAGGITECRKIATLAESYDVALALHCPLGPIALAACLQLD
HHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
AVSYNAFIQEQSLGIHYNQGSDLLDYLRNPDVFRYADGFVAIPQGPGLGIDVDEDKVCEM
HHHHHHEEEECCCCEEECCCCHHHHHHCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHH
AKTGHRWRNPVWRHADGSVAEW
HHCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKITRLETFVVPPRWLFLKIETDAGIVGWGEPIVEGRAHTVEAAVHELADYLVGQDPLRI
CCCEEEEEEEECCEEEEEEEECCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEE
EDHWQVMYRAGFYRGGPITMSAIAGIDQALWDIKGKHHGAPVHALLGGPVRERIKVYSWI
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHC
GGDRPSDVANNARAVVERGFQAVKMNGSEELQIVDTFDKVDKVIANVAAVRDAVGPYVGI
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEE
GVDFHGRVHKPMAKVLARELDPYKLMFIEEPVLSENAEALRDIANQTSTPIALGERLYSR
CCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHCCCHHHHHHHHHCCCCCHHHHHHHHHH
WDFKRILEGGYVDIVQPDASHAGGITECRKIATLAESYDVALALHCPLGPIALAACLQLD
HHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
AVSYNAFIQEQSLGIHYNQGSDLLDYLRNPDVFRYADGFVAIPQGPGLGIDVDEDKVCEM
HHHHHHEEEECCCCEEECCCCHHHHHHCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHH
AKTGHRWRNPVWRHADGSVAEW
HHCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA