Click here to switch to the map view.

The map label for this gene is glpD [H]

Identifier: 53718331

GI number: 53718331

Start: 784486

End: 786018

Strand: Reverse

Name: glpD [H]

Synonym: BPSL0688

Alternate gene names: 53718331

Gene position: 786018-784486 (Counterclockwise)

Preceding gene: 53718333

Following gene: 53718330

Centisome position: 19.29

GC content: 70.25

Gene sequence:

>1533_bases
GTGACTCAACAGAATCGTTACGATCTGCTCGTCGTCGGCGGCGGGATCAACGGCGCGGGCATCGCGCGCGATGCGGCCGG
CCGCGGCCTGTCGGTGCTCCTTTGCGAGCAGGACGACCTCGCGTCGCACACCTCCTCTTCGAGCACGAAGCTGATCCACG
GCGGGTTGCGCTACCTCGAATACAAGGAATTCGGGCTCGTGCGCAAGGCGCTGCAGGAACGCGAAACGCTGCTGCGCGCG
GCGCCGCACATCATGTGGCCGCTGCGCTTCGTGATGCCGCACATGCCGAACCTGCGCCCCGCGTGGCTCATCCGGGTCGG
CCTCTTCCTGTACGACCATCTCGCGAAACGCGAGCTGCTGCCGGGCTCGCGCGGCATCGACATGCGCCGCCATCCGGCGG
GCGCGCCGCTCGTCGATTCGATCAAGCGCGGCTTCGTCTATTCGGACGGCTGGGTCGACGATGCGCGGCTCGTCGTGCTG
AACGCGCTCGATGCGCAAGAGCGCGGCGCGCGCATCCTCACGCGCACGAAGCTCGTGTCGGCCGAGCGCCGCGACGGGCA
ATGGCATGCACGACTGCAACGCGCCGACGGCTCGACGCTCGACGTGCGGGCGCGCGCGATCGCGAACGCGGCGGGCCCGT
GGGTCGGCGAAGTGCTGCACGGCGCGCTCGGCCGCGGCGCGCAGCATAGCGTGCGCCTCGTGAAAGGCAGCCACATCATC
ACGCCGCGCCTGTTCGATCACGACCACGCATACATCTTCCAGAATCCGGACAAGCGCATCATCTTCGCGATTCCGTACGA
ACGCGACTTCACGCTGATCGGCACGACCGACGTCGAATACCGCGACGATCCGTCGCGCGTCGCGATCGACCGCGACGAAA
CGCGCTATCTGTGCGAGTCGATCAACCGCTATTTCAAGCGTAAGATCTCGCCCGCCGACGTGTGCTGGACCTACTCCGGC
GTGCGCCCGCTGCTCGAGGACGAGAACGCGGACAACCCGTCCGCCGTCACGCGCGACTACCGCCTCGAGCTCGACGACGG
CGAAGGCGCGCCGCTGCTGTCGGTGTTCGGCGGCAAGATCACGACGTTTCGCAAGCTCGCCGAAGAGGCGACCGACATGC
TGGGCGGCGCGCTCGGCGCGGCGCGCGGCGCATGGACGGCGGGGGTGCCGCTGCCGGGCGGCGACATCGCGAACGCGCGC
TTCGCGCCGTTCGCCGAGGCGTTCGCGAAACGCCACCCGTGGCTGCCCGCCGCGCTCGCGCGCCGCTATGCGCGCGCGTA
CGGCACGCGCGCCGAGCGCGTGATCGGGCGGGCCCGGTCGCTCGCCGAGCTCGGCGAGCAGCTCGCGCCCGGCCTCTACG
AAGCGGAATTGCGTTATCTGCGCGACGTCGAATGGGCGGGTTGCGCGGACGACGTGCTGTGGCGGCGTTCGAAGCTCGGC
CTGCATGTCGCGCCGGGCACGCTCGAGCCCGTGACGGCCGCGCTCGACGCCTGGTTCGGCGCCGCGCGCGAAGCGGCGAG
CGCCGCGCACTGA

Upstream 100 bases:

>100_bases
TCAAAAGCGAACTTTACTTTTTCGATTATGTTCGTTAAATTTCGAATGCGAACATTTCAGGTTCGCTCATTTTCTGTTAT
ACGAACGTTAGGATCAGCGG

Downstream 100 bases:

>100_bases
CCGGCGCGCACGACGCCGGCACCGACGAACGACGACAGGGAAACATCAGGAGTGCGCCGCGCCCGCGGCGCCAATCACAA
CTACGTACGGATGGAGATGA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTQQNRYDLLVVGGGINGAGIARDAAGRGLSVLLCEQDDLASHTSSSSTKLIHGGLRYLEYKEFGLVRKALQERETLLRA
APHIMWPLRFVMPHMPNLRPAWLIRVGLFLYDHLAKRELLPGSRGIDMRRHPAGAPLVDSIKRGFVYSDGWVDDARLVVL
NALDAQERGARILTRTKLVSAERRDGQWHARLQRADGSTLDVRARAIANAAGPWVGEVLHGALGRGAQHSVRLVKGSHII
TPRLFDHDHAYIFQNPDKRIIFAIPYERDFTLIGTTDVEYRDDPSRVAIDRDETRYLCESINRYFKRKISPADVCWTYSG
VRPLLEDENADNPSAVTRDYRLELDDGEGAPLLSVFGGKITTFRKLAEEATDMLGGALGAARGAWTAGVPLPGGDIANAR
FAPFAEAFAKRHPWLPAALARRYARAYGTRAERVIGRARSLAELGEQLAPGLYEAELRYLRDVEWAGCADDVLWRRSKLG
LHVAPGTLEPVTAALDAWFGAAREAASAAH

Sequences:

>Translated_510_residues
MTQQNRYDLLVVGGGINGAGIARDAAGRGLSVLLCEQDDLASHTSSSSTKLIHGGLRYLEYKEFGLVRKALQERETLLRA
APHIMWPLRFVMPHMPNLRPAWLIRVGLFLYDHLAKRELLPGSRGIDMRRHPAGAPLVDSIKRGFVYSDGWVDDARLVVL
NALDAQERGARILTRTKLVSAERRDGQWHARLQRADGSTLDVRARAIANAAGPWVGEVLHGALGRGAQHSVRLVKGSHII
TPRLFDHDHAYIFQNPDKRIIFAIPYERDFTLIGTTDVEYRDDPSRVAIDRDETRYLCESINRYFKRKISPADVCWTYSG
VRPLLEDENADNPSAVTRDYRLELDDGEGAPLLSVFGGKITTFRKLAEEATDMLGGALGAARGAWTAGVPLPGGDIANAR
FAPFAEAFAKRHPWLPAALARRYARAYGTRAERVIGRARSLAELGEQLAPGLYEAELRYLRDVEWAGCADDVLWRRSKLG
LHVAPGTLEPVTAALDAWFGAAREAASAAH
>Mature_509_residues
TQQNRYDLLVVGGGINGAGIARDAAGRGLSVLLCEQDDLASHTSSSSTKLIHGGLRYLEYKEFGLVRKALQERETLLRAA
PHIMWPLRFVMPHMPNLRPAWLIRVGLFLYDHLAKRELLPGSRGIDMRRHPAGAPLVDSIKRGFVYSDGWVDDARLVVLN
ALDAQERGARILTRTKLVSAERRDGQWHARLQRADGSTLDVRARAIANAAGPWVGEVLHGALGRGAQHSVRLVKGSHIIT
PRLFDHDHAYIFQNPDKRIIFAIPYERDFTLIGTTDVEYRDDPSRVAIDRDETRYLCESINRYFKRKISPADVCWTYSGV
RPLLEDENADNPSAVTRDYRLELDDGEGAPLLSVFGGKITTFRKLAEEATDMLGGALGAARGAWTAGVPLPGGDIANARF
APFAEAFAKRHPWLPAALARRYARAYGTRAERVIGRARSLAELGEQLAPGLYEAELRYLRDVEWAGCADDVLWRRSKLGL
HVAPGTLEPVTAALDAWFGAAREAASAAH

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=518, Percent_Identity=29.1505791505791, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI285002231, Length=518, Percent_Identity=29.1505791505791, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI2367226, Length=454, Percent_Identity=51.5418502202643, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1788574, Length=493, Percent_Identity=28.3975659229209, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115534726, Length=520, Percent_Identity=28.2692307692308, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17509253, Length=515, Percent_Identity=29.3203883495146, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322036, Length=575, Percent_Identity=26.0869565217391, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI161077125, Length=530, Percent_Identity=29.0566037735849, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24653942, Length=530, Percent_Identity=29.0566037735849, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24653944, Length=530, Percent_Identity=29.0566037735849, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI20130025, Length=530, Percent_Identity=29.0566037735849, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24586295, Length=393, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19921278, Length=521, Percent_Identity=24.7600767754319, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56445; Mature: 56314

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQNRYDLLVVGGGINGAGIARDAAGRGLSVLLCEQDDLASHTSSSSTKLIHGGLRYLE
CCCCCCEEEEEEECCCCCCCCCHHCCCCCCEEEEECCCHHHCCCCCCCCHHHHCCHHHHH
YKEFGLVRKALQERETLLRAAPHIMWPLRFVMPHMPNLRPAWLIRVGLFLYDHLAKRELL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PGSRGIDMRRHPAGAPLVDSIKRGFVYSDGWVDDARLVVLNALDAQERGARILTRTKLVS
CCCCCCCCCCCCCCCCHHHHHHHCCEECCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHH
AERRDGQWHARLQRADGSTLDVRARAIANAAGPWVGEVLHGALGRGAQHSVRLVKGSHII
HHCCCCHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCEEE
TPRLFDHDHAYIFQNPDKRIIFAIPYERDFTLIGTTDVEYRDDPSRVAIDRDETRYLCES
CCEEECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHH
INRYFKRKISPADVCWTYSGVRPLLEDENADNPSAVTRDYRLELDDGEGAPLLSVFGGKI
HHHHHHHCCCHHHEEEECCCCCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCH
TTFRKLAEEATDMLGGALGAARGAWTAGVPLPGGDIANARFAPFAEAFAKRHPWLPAALA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHH
RRYARAYGTRAERVIGRARSLAELGEQLAPGLYEAELRYLRDVEWAGCADDVLWRRSKLG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
LHVAPGTLEPVTAALDAWFGAAREAASAAH
EEECCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQQNRYDLLVVGGGINGAGIARDAAGRGLSVLLCEQDDLASHTSSSSTKLIHGGLRYLE
CCCCCEEEEEEECCCCCCCCCHHCCCCCCEEEEECCCHHHCCCCCCCCHHHHCCHHHHH
YKEFGLVRKALQERETLLRAAPHIMWPLRFVMPHMPNLRPAWLIRVGLFLYDHLAKRELL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PGSRGIDMRRHPAGAPLVDSIKRGFVYSDGWVDDARLVVLNALDAQERGARILTRTKLVS
CCCCCCCCCCCCCCCCHHHHHHHCCEECCCCCCCCEEEEEECCCCHHHCCCHHHHHHHHH
AERRDGQWHARLQRADGSTLDVRARAIANAAGPWVGEVLHGALGRGAQHSVRLVKGSHII
HHCCCCHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCEEE
TPRLFDHDHAYIFQNPDKRIIFAIPYERDFTLIGTTDVEYRDDPSRVAIDRDETRYLCES
CCEEECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHH
INRYFKRKISPADVCWTYSGVRPLLEDENADNPSAVTRDYRLELDDGEGAPLLSVFGGKI
HHHHHHHCCCHHHEEEECCCCCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCH
TTFRKLAEEATDMLGGALGAARGAWTAGVPLPGGDIANARFAPFAEAFAKRHPWLPAALA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHH
RRYARAYGTRAERVIGRARSLAELGEQLAPGLYEAELRYLRDVEWAGCADDVLWRRSKLG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
LHVAPGTLEPVTAALDAWFGAAREAASAAH
EEECCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]