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The map label for this gene is glmU [H]

Identifier: 53717954

GI number: 53717954

Start: 333510

End: 334871

Strand: Reverse

Name: glmU [H]

Synonym: BPSL0313

Alternate gene names: 53717954

Gene position: 334871-333510 (Counterclockwise)

Preceding gene: 53717955

Following gene: 53717953

Centisome position: 8.22

GC content: 70.26

Gene sequence:

>1362_bases
ATGAATATCGTGATTTTGGCGGCAGGCACCGGCAAGCGCATGCGTTCGGCGCTGCCGAAAGTGCTTCATCCTCTGGCCGG
CAGGCCCCTTCTCTCCCACGTGATCGATACCGCCCGCGCACTCGCGCCGTCCCGGCTCGTCGTCGTGATCGGCCATGGCG
CCGAGCAGGTGCGCGCGGCCGTCGCCGCGCCCGACGTGCAGTTCGCGGTGCAGGAGCAGCAGCTCGGCACCGGGCACGCG
GTGCGCCAGGCGCTGCCGCTGCTCGACCCGTCGCAGCCGACGCTCGTGCTGTACGGCGACGTGCCGCTCACGCGCACGGC
GACACTCAAGCGCCTCGCCGACGCCGCGACCGACGCCCGCTACGGCGTGCTGACCGTCACGCTCGACGATCCGACGGGCT
ACGGGCGCATCGTGCGCGATCAGGCCGGGTGCGTGACGCGCATCGTCGAGCAGAAGGACGCGTCGCCCGACGAGTTGCGC
ATCGACGAGATCAACACGGGCATCGTCGTCGCGCCGACCGCGCAGCTTTCGATGTGGCTCGGCGCGCTCGGCAACGACAA
CGCGCAGGGCGAGTACTACCTGACCGACGTCGTCGAGCAGGCGATCGAAGCGGGCTTCGAGATCGTCACGACGCAGCCGG
ACGACGGGTGGGAAACGCTCGGCGTGAACAGCAAGGCGCAGCTCGCCGAGCTCGAGCGCATTCATCAGCGCAACCTCGCC
GACGCGCTGCTCGCCGCGGGCGTGACGCTCGCCGATCCGGCGCGCATCGACGTGCGCGGCACGCTCGCGTGCGGGCGCGA
CGTGTCGATCGACGTGAATTGCGTGTTCGAAGGCGACGTGACGCTCGCCGACGGCGTGACGATCGGCGCGAACTGCGTGA
TCCGCCACGCTGCGATCGCCGCGGGCGCGCGCGTGGACGCGTTCTCGCATCTCGACGGCGCGACGGTCGGCGCGAACGCG
GTCGTCGGCCCGTACGCGCGGCTGCGCCCGGGTGCGGTGCTCGCCGCCGACGCGCACGTCGGCAACTTCGTCGAGGTGAA
GAACGCGACGCTCGGCCAAGGCTCGAAGGCGAACCATCTGACCTATCTCGGCGACGCGGACATCGGCGCGCGCGTGAACG
TCGGCGCGGGCACGATCACGTGCAACTACGACGGCGCGAACAAGTTCCGCACGGTCATCGAGGACGACGTGTTCGTCGGC
TCGGACACGCAGTTCGTCGCGCCGGTGCGCGTCGGCCGCGGCGTGACGGTGGCGGCGGGCACGACCGTATGGAAGGACGT
CGCCGCGGACATGCTCGTGCTCAACGACAAGACGCAGACCGCGAAGAGCGGCTACGTGCGCCCCGTCAAGAAGAAGAGCT
GA

Upstream 100 bases:

>100_bases
GGCCGCCGCCGCGCCCGGCCCGCCCGGCTGCCCAGCCGCGCCGGACGGGGCCCGCATGCTAGAATGGCCAGCTTCGAACT
CTCCCTACGAAACTGGCGCC

Downstream 100 bases:

>100_bases
ACCGTTTTTCGGGCGCGCAGCGGCGCGCCTGCATCATTGTCGAGTTTCGAAGGATAGATTTTCATGTGCGGGATTGTCGG
CGCAGTTGCGCAACGTAACA

Product: bifunctional glmU protein

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAAVAAPDVQFAVQEQQLGTGHA
VRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELR
IDEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDGWETLGVNSKAQLAELERIHQRNLA
DALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIAAGARVDAFSHLDGATVGANA
VVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVG
SDTQFVAPVRVGRGVTVAAGTTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS

Sequences:

>Translated_453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAAVAAPDVQFAVQEQQLGTGHA
VRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELR
IDEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDGWETLGVNSKAQLAELERIHQRNLA
DALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIAAGARVDAFSHLDGATVGANA
VVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVG
SDTQFVAPVRVGRGVTVAAGTTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS
>Mature_453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAAVAAPDVQFAVQEQQLGTGHA
VRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELR
IDEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDGWETLGVNSKAQLAELERIHQRNLA
DALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIAAGARVDAFSHLDGATVGANA
VVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVG
SDTQFVAPVRVGRGVTVAAGTTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=452, Percent_Identity=54.4247787610619, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 47508; Mature: 47508

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAA
CEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
VAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDAR
HCCCCCEEEEEHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
YGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELRIDEINTGIVVAPTAQLSMWL
EEEEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEEEECHHHHHHHH
GALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDGWETLGVNSKAQLAELERIHQRNLA
HHCCCCCCCCCEEHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
DALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIA
HHHHHCCCEECCCCEEEEEEEEECCCCCEEEEEEEEECCEEEECCEEECCHHHEEHHHHH
AGARVDAFSHLDGATVGANAVVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHL
CCCCCCHHHCCCCCCCCCCCEECCHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCE
TYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAG
EEECCCCCCCEEECCCEEEEEECCCCHHHHHHHCCCEEECCCCCEEEEEECCCCEEEEEC
TTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS
CHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAA
CEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
VAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDAR
HCCCCCEEEEEHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
YGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELRIDEINTGIVVAPTAQLSMWL
EEEEEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEEEECHHHHHHHH
GALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDGWETLGVNSKAQLAELERIHQRNLA
HHCCCCCCCCCEEHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
DALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIA
HHHHHCCCEECCCCEEEEEEEEECCCCCEEEEEEEEECCEEEECCEEECCHHHEEHHHHH
AGARVDAFSHLDGATVGANAVVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHL
CCCCCCHHHCCCCCCCCCCCEECCHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCE
TYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAG
EEECCCCCCCEEECCCEEEEEECCCCHHHHHHHCCCEEECCCCCEEEEEECCCCEEEEEC
TTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS
CHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA