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The map label for this gene is rodA [H]

Identifier: 53717824

GI number: 53717824

Start: 186311

End: 187459

Strand: Reverse

Name: rodA [H]

Synonym: BPSL0182

Alternate gene names: 53717824

Gene position: 187459-186311 (Counterclockwise)

Preceding gene: 53717825

Following gene: 53717818

Centisome position: 4.6

GC content: 65.36

Gene sequence:

>1149_bases
ATGCAATTCGACAAGCGCGCCTCGCTCGACAAGATCAAGCAGATGTTCGCGGGCTTCGACCGGCCGCTCGCGCTCATCGT
GTTCCTGCTGCTGTGCGTCGGCATCGTCACGCTGTACAGCGCGAGCGTCGACGTGCCGGGGCGCGTCGAGGACCAGTTGC
GCAACATCATGCTGACGTTCGTGCTGATGTGGGTGATCGCGAACATCCCGCCGCAAACGCTGATGCGCTTCGCGGTGCCG
CTCTATTCGTTCGGCGTCGCGCTGCTCGTCGCGGTGGCGCTATTCGGCATGACGAAGAAGGGCGCGAAGCGCTGGCTGAA
CGTCGGCGTCGTGATCCAGCCGTCCGAGATCCTCAAGATCGCGACGCCGCTGATGCTCGCGTGGTACTACCAGCGGCGCG
AAAGCAGCCTGCGCTGGTACGACTTCGTCGTCGCGTTCGCCATCCTGATGGTGCCCGTCGGGCTGATCGCGAAACAGCCG
GATCTCGGCACCGCCGTGCTCGTGTTCGCCGCGGGCCTGTTCGTGATCTATCTCGCGGGGCTGTCGTTCAAGCTGATCGT
GCCGGTGCTCGTCGCCGGCGTGCTCGCGGTCGGCTCGATCGCCGTGTTCGAGGAGCGCATCTGCCAGCCCGAAGTCGTCT
GGCCGCTGATGCACGACTATCAGAAACACCGCGTCTGCACGCTGCTCGATCCGACGTCCGACCCGCTCGGCAAAGGCTTC
CACACGATCCAGGCGGTGATCGCGATCGGCTCGGGCGGCCCGCTCGGCAAGGGGTATCTGAAGGGCACGCAGGCGCACCT
CGAATTCATTCCGGAAAAGCACACCGATTTCATCTTCGCGGTGTTTTCCGAGGAATTCGGGCTCGTCGGCGGGCTCGTGC
TGCTGACGCTGTACATGGCGCTGATCGCGCGCGGGCTCTACATCGCCGCGCAGGGCGCGACGCTGTTCGGGCGGCTGCTC
GCCGGCTCGCTCACGCTCGCGTTCTTCGTCTACGCGTTCGTCAATATCGGAATGGTGAGCGGCGTGCTGCCCGTCGTCGG
CGTGCCGCTGCCGTTCATGAGCTACGGCGGCACGGCGCTCACGACGCTCGGCATCGCCGTCGGGCTCATCATGAGCGTCG
GGCGGCAGAAGCGGCTGATGAAGAGTTGA

Upstream 100 bases:

>100_bases
CCTCATCGGGCGCCCCGAAGACACCCGCTCAGGACGACAACCATGCCGTCTCCGCCGCCAGGCCGGCGGCGGGCGGCATC
GACGAGTAACGGAGACAGGC

Downstream 100 bases:

>100_bases
TCGAAGCGGCGCGGCGCGCCGCTTTTTTCGTGGCGATGCCGGCGGGCGGGGGCCGGCCACGGTTGGCGGTTGGCGGTTGG
CGGTTGGCGGTTGGCGGTTG

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFDKRASLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASVDVPGRVEDQLRNIMLTFVLMWVIANIPPQTLMRFAVP
LYSFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRRESSLRWYDFVVAFAILMVPVGLIAKQP
DLGTAVLVFAAGLFVIYLAGLSFKLIVPVLVAGVLAVGSIAVFEERICQPEVVWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGPLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEFGLVGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAVGLIMSVGRQKRLMKS

Sequences:

>Translated_382_residues
MQFDKRASLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASVDVPGRVEDQLRNIMLTFVLMWVIANIPPQTLMRFAVP
LYSFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRRESSLRWYDFVVAFAILMVPVGLIAKQP
DLGTAVLVFAAGLFVIYLAGLSFKLIVPVLVAGVLAVGSIAVFEERICQPEVVWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGPLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEFGLVGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAVGLIMSVGRQKRLMKS
>Mature_382_residues
MQFDKRASLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASVDVPGRVEDQLRNIMLTFVLMWVIANIPPQTLMRFAVP
LYSFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRRESSLRWYDFVVAFAILMVPVGLIAKQP
DLGTAVLVFAAGLFVIYLAGLSFKLIVPVLVAGVLAVGSIAVFEERICQPEVVWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGPLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEFGLVGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALTTLGIAVGLIMSVGRQKRLMKS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=380, Percent_Identity=49.2105263157895, Blast_Score=294, Evalue=6e-81,
Organism=Escherichia coli, GI1786277, Length=389, Percent_Identity=29.5629820051414, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41564; Mature: 41564

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKRASLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASVDVPGRVEDQLRNIMLTF
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWVIANIPPQTLMRFAVPLYSFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRRESSLRWYDFVVAFAILMVPVGLIAKQPDLGTAVLVFAAGLFVIYLAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
LSFKLIVPVLVAGVLAVGSIAVFEERICQPEVVWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGPLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEFGLVGGLVLLTLYMA
HHHHHHHHCCCCCCCCCHHHCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAVGLIMSVGRQKRLMKS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFDKRASLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSASVDVPGRVEDQLRNIMLTF
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWVIANIPPQTLMRFAVPLYSFGVALLVAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRRESSLRWYDFVVAFAILMVPVGLIAKQPDLGTAVLVFAAGLFVIYLAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
LSFKLIVPVLVAGVLAVGSIAVFEERICQPEVVWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGPLGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEFGLVGGLVLLTLYMA
HHHHHHHHCCCCCCCCCHHHCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGIAVGLIMSVGRQKRLMKS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]