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The map label for this gene is ycgO [H]

Identifier: 52787736

GI number: 52787736

Start: 3882604

End: 3884070

Strand: Reverse

Name: ycgO [H]

Synonym: BLi04059

Alternate gene names: 52787736

Gene position: 3884070-3882604 (Counterclockwise)

Preceding gene: 52787737

Following gene: 52787733

Centisome position: 91.98

GC content: 48.81

Gene sequence:

>1467_bases
ATGAATTACGGAATTTTAATATCGATAGGTATTTATATGGCGGGAATGCTTTTCATCGGATATTTTGCATATCGCAGGAC
ATCAAATTTGACCGATTACATGCTTGGCGGAAGAAATCTGGGTCCCGCCGTTACCGCGTTAAGCGCAGGAGCTTCCGATA
TGAGCGGCTGGCTATTAATGGGGCTGCCCGGTGCGATGTTCCTGAACGGATTGAGCAGCGGCTGGATCGTTGTCGGTCTG
ACAATCGGCGCTTATTTGAACTGGGTGTATGTCGCGCCGAGGCTAAGGACGTATACGGAAACGGCCGGCAACAGCATTAC
TATACCCGATTATTTCGAAAACCGTTTTAAAGACGGTTCAAGACTGTTACGGATGACGTCGGCTTTTGTTATTTTAGTAT
TTTTCACTTTTTATACATCATCCGGAATGGTGGCGGGCGGAGAGCTGTTCAGAACCGCATTCCACCTGGATTATCGGATC
GGCATCTGGCTGACGGCCGGGGTTGTCATTCTTTATACGCTCTTCGGAGGCTTTTTGGCTGTCAGCTGGACCGATTTTGT
TCAAGGGACGATCATGTTTATCGCGCTCATCTTAATGCCGGTAGTCGTGTTTGTTCAACTGGGGGGAATTGCGCCGGCGT
TTTCGGAAGTGAACGCGGTTAACCCGGATCTCCTCCGTCCGTTTCAAGGAACAACCGTAATCGGTATCATATCTTTACTG
GCATGGGGTCTCGGCTACTTTGGACAGCCTCATATTATTGTCAGGTTTATGGCGATTTCAAGCGTGAAAGAATTGAAGAG
TGCCAGAAGAATCGGCATGGGCTGGATGATCTTTTCGATTTGCGGAGCGATGCTGACAGGACTCGTCGGCATTGCCTATT
TCAGTGCGAATCATCTTACGTTAAAGAATGCCGAGACGATATTCATTAAGCTTGCCGACCTTTTGTTCCCTTCAATGATT
ACGGGGTTCTTGCTGGCCGCCATATTAGCAGCGGTGATGAGCACAATTTCTTCACAGCTTCTTGTAACCTCAAGCGCGCT
GACAGAGGATTTTTATAAAGCGTTTATCCGGAAAGGGGCTTCTGATAAAGAACTTGTACTTGTCGGAAGGCTGTCTGTCC
TCGCCATTTCACTGATCGCACTCTTGATGGCGCTTCATCCGAATGAAACGATTCTGAATCTTGTCGGCTATGCATGGGCA
GGCTTCGGGGCGGCATTTGGCCCTGTCGTTTTGCTGAGCCTGTATTGGAAACGAATGACGAAGTGGGGCGCGCTTGCAGG
GATGCTGTCCGGAGCGCTGACCGTTATTGTGTGGGAGCAAGTGAAAGCGTTTGACCCGGTTTATGAAATCATTCCCGGAT
TTATTGTTTGTACAGTCGTGATCATCGCCGTCAGCCTGATGACAAAGAAGCCGCGGGCAGAGATTGAAAAGGAATTTGAG
ACTGCGGTTGAACAGCTGAAAGGTTGA

Upstream 100 bases:

>100_bases
AATGTAAGGCTGGAGAAAAAATTTGCGATAAAAACAATACCTGTCGGTCAATTATTCATGTATATTGATATTACGCAAAT
CACACAGGCAGGGGGAAGCT

Downstream 100 bases:

>100_bases
GAATCTAGTGATGGCCTTTGTCAAAGTATTGTTGACGACCGCTTTTCTCACAGGGGCTTTCGCAGGATTCCTGTGGGCAT
TTTCCAAAGAAAAAGGCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNYGILISIGIYMAGMLFIGYFAYRRTSNLTDYMLGGRNLGPAVTALSAGASDMSGWLLMGLPGAMFLNGLSSGWIVVGL
TIGAYLNWVYVAPRLRTYTETAGNSITIPDYFENRFKDGSRLLRMTSAFVILVFFTFYTSSGMVAGGELFRTAFHLDYRI
GIWLTAGVVILYTLFGGFLAVSWTDFVQGTIMFIALILMPVVVFVQLGGIAPAFSEVNAVNPDLLRPFQGTTVIGIISLL
AWGLGYFGQPHIIVRFMAISSVKELKSARRIGMGWMIFSICGAMLTGLVGIAYFSANHLTLKNAETIFIKLADLLFPSMI
TGFLLAAILAAVMSTISSQLLVTSSALTEDFYKAFIRKGASDKELVLVGRLSVLAISLIALLMALHPNETILNLVGYAWA
GFGAAFGPVVLLSLYWKRMTKWGALAGMLSGALTVIVWEQVKAFDPVYEIIPGFIVCTVVIIAVSLMTKKPRAEIEKEFE
TAVEQLKG

Sequences:

>Translated_488_residues
MNYGILISIGIYMAGMLFIGYFAYRRTSNLTDYMLGGRNLGPAVTALSAGASDMSGWLLMGLPGAMFLNGLSSGWIVVGL
TIGAYLNWVYVAPRLRTYTETAGNSITIPDYFENRFKDGSRLLRMTSAFVILVFFTFYTSSGMVAGGELFRTAFHLDYRI
GIWLTAGVVILYTLFGGFLAVSWTDFVQGTIMFIALILMPVVVFVQLGGIAPAFSEVNAVNPDLLRPFQGTTVIGIISLL
AWGLGYFGQPHIIVRFMAISSVKELKSARRIGMGWMIFSICGAMLTGLVGIAYFSANHLTLKNAETIFIKLADLLFPSMI
TGFLLAAILAAVMSTISSQLLVTSSALTEDFYKAFIRKGASDKELVLVGRLSVLAISLIALLMALHPNETILNLVGYAWA
GFGAAFGPVVLLSLYWKRMTKWGALAGMLSGALTVIVWEQVKAFDPVYEIIPGFIVCTVVIIAVSLMTKKPRAEIEKEFE
TAVEQLKG
>Mature_488_residues
MNYGILISIGIYMAGMLFIGYFAYRRTSNLTDYMLGGRNLGPAVTALSAGASDMSGWLLMGLPGAMFLNGLSSGWIVVGL
TIGAYLNWVYVAPRLRTYTETAGNSITIPDYFENRFKDGSRLLRMTSAFVILVFFTFYTSSGMVAGGELFRTAFHLDYRI
GIWLTAGVVILYTLFGGFLAVSWTDFVQGTIMFIALILMPVVVFVQLGGIAPAFSEVNAVNPDLLRPFQGTTVIGIISLL
AWGLGYFGQPHIIVRFMAISSVKELKSARRIGMGWMIFSICGAMLTGLVGIAYFSANHLTLKNAETIFIKLADLLFPSMI
TGFLLAAILAAVMSTISSQLLVTSSALTEDFYKAFIRKGASDKELVLVGRLSVLAISLIALLMALHPNETILNLVGYAWA
GFGAAFGPVVLLSLYWKRMTKWGALAGMLSGALTVIVWEQVKAFDPVYEIIPGFIVCTVVIIAVSLMTKKPRAEIEKEFE
TAVEQLKG

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=493, Percent_Identity=55.578093306288, Blast_Score=537, Evalue=1e-152,
Organism=Homo sapiens, GI110835708, Length=545, Percent_Identity=22.7522935779817, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI11141885, Length=453, Percent_Identity=26.2693156732892, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI109659836, Length=437, Percent_Identity=22.6544622425629, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI109659839, Length=453, Percent_Identity=21.6335540838852, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787251, Length=483, Percent_Identity=55.4865424430642, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1790503, Length=509, Percent_Identity=28.0943025540275, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87082237, Length=448, Percent_Identity=30.1339285714286, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790113, Length=475, Percent_Identity=22.3157894736842, Blast_Score=79, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115533094, Length=481, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221459584, Length=373, Percent_Identity=24.1286863270777, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221459588, Length=378, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221459586, Length=375, Percent_Identity=24, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24645928, Length=390, Percent_Identity=25.3846153846154, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24651739, Length=372, Percent_Identity=22.8494623655914, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640370, Length=356, Percent_Identity=24.1573033707865, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53116; Mature: 53116

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYGILISIGIYMAGMLFIGYFAYRRTSNLTDYMLGGRNLGPAVTALSAGASDMSGWLLM
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHCCCCCCCCEEEE
GLPGAMFLNGLSSGWIVVGLTIGAYLNWVYVAPRLRTYTETAGNSITIPDYFENRFKDGS
CCCHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHCCCCEEECCHHHHHHHCCHH
RLLRMTSAFVILVFFTFYTSSGMVAGGELFRTAFHLDYRIGIWLTAGVVILYTLFGGFLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSWTDFVQGTIMFIALILMPVVVFVQLGGIAPAFSEVNAVNPDLLRPFQGTTVIGIISLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCCCCCHHHHHHHHH
AWGLGYFGQPHIIVRFMAISSVKELKSARRIGMGWMIFSICGAMLTGLVGIAYFSANHLT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
LKNAETIFIKLADLLFPSMITGFLLAAILAAVMSTISSQLLVTSSALTEDFYKAFIRKGA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDKELVLVGRLSVLAISLIALLMALHPNETILNLVGYAWAGFGAAFGPVVLLSLYWKRMT
CCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWGALAGMLSGALTVIVWEQVKAFDPVYEIIPGFIVCTVVIIAVSLMTKKPRAEIEKEFE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TAVEQLKG
HHHHHHCC
>Mature Secondary Structure
MNYGILISIGIYMAGMLFIGYFAYRRTSNLTDYMLGGRNLGPAVTALSAGASDMSGWLLM
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHCCCCCCCCEEEE
GLPGAMFLNGLSSGWIVVGLTIGAYLNWVYVAPRLRTYTETAGNSITIPDYFENRFKDGS
CCCHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHCCCCEEECCHHHHHHHCCHH
RLLRMTSAFVILVFFTFYTSSGMVAGGELFRTAFHLDYRIGIWLTAGVVILYTLFGGFLA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSWTDFVQGTIMFIALILMPVVVFVQLGGIAPAFSEVNAVNPDLLRPFQGTTVIGIISLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCCCCCHHHHHHHHH
AWGLGYFGQPHIIVRFMAISSVKELKSARRIGMGWMIFSICGAMLTGLVGIAYFSANHLT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
LKNAETIFIKLADLLFPSMITGFLLAAILAAVMSTISSQLLVTSSALTEDFYKAFIRKGA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDKELVLVGRLSVLAISLIALLMALHPNETILNLVGYAWAGFGAAFGPVVLLSLYWKRMT
CCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWGALAGMLSGALTVIVWEQVKAFDPVYEIIPGFIVCTVVIIAVSLMTKKPRAEIEKEFE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TAVEQLKG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]