Click here to switch to the map view.

The map label for this gene is xylR [H]

Identifier: 52787726

GI number: 52787726

Start: 3876100

End: 3877263

Strand: Direct

Name: xylR [H]

Synonym: BLi04049

Alternate gene names: 52787726

Gene position: 3876100-3877263 (Clockwise)

Preceding gene: 52787723

Following gene: 52787727

Centisome position: 91.79

GC content: 48.11

Gene sequence:

>1164_bases
TTGAATACAGCGGATCAAGCCCTTGTAAAAAAAATGAACAAAGCCCTGATTTTTGAGCAGATTATTGAAAACGGACCCGT
CTCAAGGGCCAAACTTTCGGAAATAACAGGATTAAATAAAGCGACCGTTTCCTCCCAAGTGTCTTCCCTGCTTCAAAAGG
ACATCATTTATGAAACCGGCCCCGGCGAGTCAAGCGGCGGCAGAAGGCCCGTTATGCTGAAATTCAATCGAAAAGCCGGC
TATGCGGTCGGTGTAGATGTCGGAACCAATTATATAATTGTTGCGTTAACCGACCTTGAAGGGCATTTGATTGAACAATT
CGAACGAACGCTTGATGAAGAAGACATTCAGGCGACAGAAGAGGCATTAATCGAATTGACGGGGCTTGCCGTTGACAAAA
TACCGCCTTCCCCATTCGGATTGACCGGAATCGGCGTGTGCGTGCCCGGCTTGGTGGACAACGAACGGCATGTAGTCTTT
ACGCCAAATAAGCCGATCCATTTGATTCCGATAAAAGAAAAACTGGAAGAAAGGTTCGGCGTTCCCATTTTAATTGAAAA
CGAAGCCAACGCCGGCGCCGTTGGCGAGAAGGAATACGGGGAAGGCGGCCAGCTTGAGCATGCCGTGTTTGTCAGCATTA
ATACCGGGATCGGTTTAGGGATTTTAATGAATGGAAAATTGTTTAGAGGTGTGCAAGGTTTTTCCGGAGAAGCCGGGCAC
ATGTCCATTCACTTTGACGGTCCGTTATGCCGGTGCGGAAATAGAGGCTGCTGGGAGCTTTACGCTTCAGAAAAAGCCGT
CTTCTCTCACTATGCAGCGAATTCCGGGGCCCAGCTTTACGAAACCGTTAAAGAACTTGCAGACCGCGGTGATCCGGGCA
TGATGGAGACGTTTGAACGCTTTGGCTTTCATATCGGCATCGGGCTTCTCAACATCTTGAAAACGTTGAATCCCGACACC
ATTATCTTGCGGAATACCATAGTGGAATCCTATCCGAGCATCGTCGATGCGATCAAAAAAACGATTGCCTCAAGAAGCGC
AGCAGAAGCCTTGTCTAATTATCATTTAAAAATCTCCACGCTCGGCCGCACCGCCTCAGCGCTTGGGATGTCCTCCCTTG
TAACCGAACGTTTTCTGGAACGGTTTATGAACGAGAGATTTTAA

Upstream 100 bases:

>100_bases
TCAATTAATCGCTTTCAATGGAAATAGAGGAAAAAATAAGTTTTCAAAATTTGTTATACTATAATAAATTCACAGCTTCA
AAGCAATGGAGTGATTGACA

Downstream 100 bases:

>100_bases
TCTTCATATAAAAAAGCGCATATTCCATTTAGGAATGTGCGTTTTGCAGATTGTTGATAAAATCCCAAAACGGCTTTTTG
TTTTGGGATTTTATCATCCT

Product: XylR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNTADQALVKKMNKALIFEQIIENGPVSRAKLSEITGLNKATVSSQVSSLLQKDIIYETGPGESSGGRRPVMLKFNRKAG
YAVGVDVGTNYIIVALTDLEGHLIEQFERTLDEEDIQATEEALIELTGLAVDKIPPSPFGLTGIGVCVPGLVDNERHVVF
TPNKPIHLIPIKEKLEERFGVPILIENEANAGAVGEKEYGEGGQLEHAVFVSINTGIGLGILMNGKLFRGVQGFSGEAGH
MSIHFDGPLCRCGNRGCWELYASEKAVFSHYAANSGAQLYETVKELADRGDPGMMETFERFGFHIGIGLLNILKTLNPDT
IILRNTIVESYPSIVDAIKKTIASRSAAEALSNYHLKISTLGRTASALGMSSLVTERFLERFMNERF

Sequences:

>Translated_387_residues
MNTADQALVKKMNKALIFEQIIENGPVSRAKLSEITGLNKATVSSQVSSLLQKDIIYETGPGESSGGRRPVMLKFNRKAG
YAVGVDVGTNYIIVALTDLEGHLIEQFERTLDEEDIQATEEALIELTGLAVDKIPPSPFGLTGIGVCVPGLVDNERHVVF
TPNKPIHLIPIKEKLEERFGVPILIENEANAGAVGEKEYGEGGQLEHAVFVSINTGIGLGILMNGKLFRGVQGFSGEAGH
MSIHFDGPLCRCGNRGCWELYASEKAVFSHYAANSGAQLYETVKELADRGDPGMMETFERFGFHIGIGLLNILKTLNPDT
IILRNTIVESYPSIVDAIKKTIASRSAAEALSNYHLKISTLGRTASALGMSSLVTERFLERFMNERF
>Mature_387_residues
MNTADQALVKKMNKALIFEQIIENGPVSRAKLSEITGLNKATVSSQVSSLLQKDIIYETGPGESSGGRRPVMLKFNRKAG
YAVGVDVGTNYIIVALTDLEGHLIEQFERTLDEEDIQATEEALIELTGLAVDKIPPSPFGLTGIGVCVPGLVDNERHVVF
TPNKPIHLIPIKEKLEERFGVPILIENEANAGAVGEKEYGEGGQLEHAVFVSINTGIGLGILMNGKLFRGVQGFSGEAGH
MSIHFDGPLCRCGNRGCWELYASEKAVFSHYAANSGAQLYETVKELADRGDPGMMETFERFGFHIGIGLLNILKTLNPDT
IILRNTIVESYPSIVDAIKKTIASRSAAEALSNYHLKISTLGRTASALGMSSLVTERFLERFMNERF

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=281, Percent_Identity=28.1138790035587, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI298566315, Length=281, Percent_Identity=28.1138790035587, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4885285, Length=281, Percent_Identity=28.1138790035587, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI190014632, Length=281, Percent_Identity=28.1138790035587, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1786891, Length=384, Percent_Identity=28.3854166666667, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787878, Length=369, Percent_Identity=24.6612466124661, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787363, Length=268, Percent_Identity=27.6119402985075, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082127, Length=166, Percent_Identity=27.1084337349398, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081733, Length=272, Percent_Identity=25.7352941176471, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42127; Mature: 42127

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTADQALVKKMNKALIFEQIIENGPVSRAKLSEITGLNKATVSSQVSSLLQKDIIYETG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCEEECC
PGESSGGRRPVMLKFNRKAGYAVGVDVGTNYIIVALTDLEGHLIEQFERTLDEEDIQATE
CCCCCCCCCCEEEEECCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHH
EALIELTGLAVDKIPPSPFGLTGIGVCVPGLVDNERHVVFTPNKPIHLIPIKEKLEERFG
HHHHHHHCCEEECCCCCCCCCCCHHHHCCCCCCCCCEEEECCCCCEEEEECHHHHHHHCC
VPILIENEANAGAVGEKEYGEGGQLEHAVFVSINTGIGLGILMNGKLFRGVQGFSGEAGH
CCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCHHHCCCCCCCCCCCE
MSIHFDGPLCRCGNRGCWELYASEKAVFSHYAANSGAQLYETVKELADRGDPGMMETFER
EEEEECCCCEECCCCCCEEHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHH
FGFHIGIGLLNILKTLNPDTIILRNTIVESYPSIVDAIKKTIASRSAAEALSNYHLKIST
CCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
LGRTASALGMSSLVTERFLERFMNERF
CCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTADQALVKKMNKALIFEQIIENGPVSRAKLSEITGLNKATVSSQVSSLLQKDIIYETG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCEEECC
PGESSGGRRPVMLKFNRKAGYAVGVDVGTNYIIVALTDLEGHLIEQFERTLDEEDIQATE
CCCCCCCCCCEEEEECCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHH
EALIELTGLAVDKIPPSPFGLTGIGVCVPGLVDNERHVVFTPNKPIHLIPIKEKLEERFG
HHHHHHHCCEEECCCCCCCCCCCHHHHCCCCCCCCCEEEECCCCCEEEEECHHHHHHHCC
VPILIENEANAGAVGEKEYGEGGQLEHAVFVSINTGIGLGILMNGKLFRGVQGFSGEAGH
CCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCHHHCCCCCCCCCCCE
MSIHFDGPLCRCGNRGCWELYASEKAVFSHYAANSGAQLYETVKELADRGDPGMMETFER
EEEEECCCCEECCCCCCEEHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHH
FGFHIGIGLLNILKTLNPDTIILRNTIVESYPSIVDAIKKTIASRSAAEALSNYHLKIST
CCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
LGRTASALGMSSLVTERFLERFMNERF
CCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]