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The map label for this gene is ywcA [H]

Identifier: 52787723

GI number: 52787723

Start: 3871472

End: 3873010

Strand: Direct

Name: ywcA [H]

Synonym: BLi04046

Alternate gene names: 52787723

Gene position: 3871472-3873010 (Clockwise)

Preceding gene: 52787722

Following gene: 52787726

Centisome position: 91.68

GC content: 49.64

Gene sequence:

>1539_bases
ATGAGTGCCACAGCCTTTATTTTGTTTCTTGCCATTGTCGCCCTCACGCTTGTCATTACGTATTTCGCCGCTAAACAGAC
AAAAACGGCCAATGAGTTTTACACGGCGGGAGGGGGACTTACCGGCATTCAAAACGGACTGGCTATTGCGGGAGATTACA
TGTCAGCGGCTTCTTTCCTCGGAATTGCCGGGATGATCGCTTTGAACGGGTTTGACGGTTTCTTCTACAGCATCGGCTTC
CTCGTCGCTTATTTAGTTGTCCTTTATATTGTGGCAGAACCGCTCCGAAACCTCGGCAAATTTACAATGGCGGACATGAT
TGCCTCTCGTTTTAAACAAAAGAAAATTCGCGGTGTCGCCGCATTAAACACAATCACGATCTCCACCTTTTATATGATTG
CACAGTTAGTCGGCGCCGGCGCGCTGATCAAGCTTCTGCTCGGCATCGATTATACGCTGGCAGTGTGCATTGTCGGGGTT
TTGATGACCATCTACGTCGTATTCGGAGGAATGATTGCAACCAGCTGGGTCCAGATCATCAAGGCCGTTCTTTTGATGGC
GGGGACGCTAATCATTTCGGTCATCGTTTTTTCAAAATTCGGCTTCAGCCTGACGAACATGTTCGAACAAATGAAAACAG
CTACTCCGCTCGGGGCGGATTTTCTAAACCCCGGCAATAAGTATAAAGTTCCTCTTGAAACACTTTCACTCAATTTGGCG
CTCGTCCTTGGAACAGCCGGCCTGCCCCACATTCTCATCCGCTTTTATACAGTAAAAGATGCCAAAACGGCAAGGAAATC
GGTTGTCTCGGCAACATGGATTATCGGTATATTTTATATTATGACGGTCTTTCTCGGTTTTGGTGCTGCCGCTTTTGTCG
GTTTTGAAAACATTTTAGCTGCCGATAAAGCGGGGAATATGGCCGCACCGCTGCTTGCTCAGGCGCTCGGCGGAGATTTT
CTGTTCGCCTTCGTCTCAGCCATCGCTTTCGCCACGATTTTGGCGGTAGTTACAGGACTTGTCCTGTCGGCGGCTTCTGC
TTTTGCGCATGATATATACAGCCAGATTATCAGAAAAGGCGCGGCTACGGAAAAAGAGCAAATGATTGCTGCAAGGTGGG
CTTCCATCGGCGTATCCGTCCTTTCAATTCTGCTTGCTGTCTTTGCCCAATCGCTGAATGTCGCGTTTCTTGTCTCGCTA
GCATTTGCCGTGGCGGCAAGCGCCAATTTGCCGCTTATTATCTTCACCGTCTTCTGGAAAAGATTCAATGCCGCCGGCGC
TTTGGCCGGCAGCCTGACCGGCCTTTTAAGCGCTCTGATCCTTGTCTCCATCAGCCCGAGCGTATGGGACCCGGCCGGAA
ACGCCATCTTTGTTGGAGACCCGCTCATCCCGCTTTCCAACCCGGGAATCATCTCTATTCCGCTCGGCTTTTTAGGCGCT
TATCTTGGAACGATTCTATCTTCAAAAACCCCTGGTCAAGACGCGTTTGCAGAAATTCAGGTCAAAGCGCATACAGGCAT
CCACATGGATCAATCTTAA

Upstream 100 bases:

>100_bases
TTGTTATGACGTGGACGCTGTGCATTGTGTATACGAAAAAAGCCGGTCAATTCGATCAAATTGCAAGCGATTTCAAAAAG
AAGATTGGAGGCGTTGATTC

Downstream 100 bases:

>100_bases
ACCGTGTGCAGCCGAAAAAAACTTATGAGCCGGCCGGCCCATAAGTTTTTATTTATTCCCGAAAGCTTGCCAGCCGCTCG
TTCAGCGTTTTCGTGTGCCG

Product: YwcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSATAFILFLAIVALTLVITYFAAKQTKTANEFYTAGGGLTGIQNGLAIAGDYMSAASFLGIAGMIALNGFDGFFYSIGF
LVAYLVVLYIVAEPLRNLGKFTMADMIASRFKQKKIRGVAALNTITISTFYMIAQLVGAGALIKLLLGIDYTLAVCIVGV
LMTIYVVFGGMIATSWVQIIKAVLLMAGTLIISVIVFSKFGFSLTNMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
LVLGTAGLPHILIRFYTVKDAKTARKSVVSATWIIGIFYIMTVFLGFGAAAFVGFENILAADKAGNMAAPLLAQALGGDF
LFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGAATEKEQMIAARWASIGVSVLSILLAVFAQSLNVAFLVSL
AFAVAASANLPLIIFTVFWKRFNAAGALAGSLTGLLSALILVSISPSVWDPAGNAIFVGDPLIPLSNPGIISIPLGFLGA
YLGTILSSKTPGQDAFAEIQVKAHTGIHMDQS

Sequences:

>Translated_512_residues
MSATAFILFLAIVALTLVITYFAAKQTKTANEFYTAGGGLTGIQNGLAIAGDYMSAASFLGIAGMIALNGFDGFFYSIGF
LVAYLVVLYIVAEPLRNLGKFTMADMIASRFKQKKIRGVAALNTITISTFYMIAQLVGAGALIKLLLGIDYTLAVCIVGV
LMTIYVVFGGMIATSWVQIIKAVLLMAGTLIISVIVFSKFGFSLTNMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
LVLGTAGLPHILIRFYTVKDAKTARKSVVSATWIIGIFYIMTVFLGFGAAAFVGFENILAADKAGNMAAPLLAQALGGDF
LFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGAATEKEQMIAARWASIGVSVLSILLAVFAQSLNVAFLVSL
AFAVAASANLPLIIFTVFWKRFNAAGALAGSLTGLLSALILVSISPSVWDPAGNAIFVGDPLIPLSNPGIISIPLGFLGA
YLGTILSSKTPGQDAFAEIQVKAHTGIHMDQS
>Mature_511_residues
SATAFILFLAIVALTLVITYFAAKQTKTANEFYTAGGGLTGIQNGLAIAGDYMSAASFLGIAGMIALNGFDGFFYSIGFL
VAYLVVLYIVAEPLRNLGKFTMADMIASRFKQKKIRGVAALNTITISTFYMIAQLVGAGALIKLLLGIDYTLAVCIVGVL
MTIYVVFGGMIATSWVQIIKAVLLMAGTLIISVIVFSKFGFSLTNMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLAL
VLGTAGLPHILIRFYTVKDAKTARKSVVSATWIIGIFYIMTVFLGFGAAAFVGFENILAADKAGNMAAPLLAQALGGDFL
FAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGAATEKEQMIAARWASIGVSVLSILLAVFAQSLNVAFLVSLA
FAVAASANLPLIIFTVFWKRFNAAGALAGSLTGLLSALILVSISPSVWDPAGNAIFVGDPLIPLSNPGIISIPLGFLGAY
LGTILSSKTPGQDAFAEIQVKAHTGIHMDQS

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=436, Percent_Identity=24.7706422018349, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI14140236, Length=444, Percent_Identity=20.7207207207207, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790503, Length=519, Percent_Identity=45.8574181117534, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1787251, Length=436, Percent_Identity=26.3761467889908, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI87082237, Length=435, Percent_Identity=22.7586206896552, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53854; Mature: 53722

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATAFILFLAIVALTLVITYFAAKQTKTANEFYTAGGGLTGIQNGLAIAGDYMSAASFL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCHHHCCCCEEECHHHHHHHHH
GIAGMIALNGFDGFFYSIGFLVAYLVVLYIVAEPLRNLGKFTMADMIASRFKQKKIRGVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNTITISTFYMIAQLVGAGALIKLLLGIDYTLAVCIVGVLMTIYVVFGGMIATSWVQII
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLLMAGTLIISVIVFSKFGFSLTNMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHCCCCCCEECCHHHHHHHHH
LVLGTAGLPHILIRFYTVKDAKTARKSVVSATWIIGIFYIMTVFLGFGAAAFVGFENILA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADKAGNMAAPLLAQALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKG
HCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AATEKEQMIAARWASIGVSVLSILLAVFAQSLNVAFLVSLAFAVAASANLPLIIFTVFWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RFNAAGALAGSLTGLLSALILVSISPSVWDPAGNAIFVGDPLIPLSNPGIISIPLGFLGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHHHHH
YLGTILSSKTPGQDAFAEIQVKAHTGIHMDQS
HHHHHHCCCCCCCCCHHEEEEEECCCCCCCCC
>Mature Secondary Structure 
SATAFILFLAIVALTLVITYFAAKQTKTANEFYTAGGGLTGIQNGLAIAGDYMSAASFL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCHHHCCCCEEECHHHHHHHHH
GIAGMIALNGFDGFFYSIGFLVAYLVVLYIVAEPLRNLGKFTMADMIASRFKQKKIRGVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNTITISTFYMIAQLVGAGALIKLLLGIDYTLAVCIVGVLMTIYVVFGGMIATSWVQII
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLLMAGTLIISVIVFSKFGFSLTNMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHCCCCCCEECCHHHHHHHHH
LVLGTAGLPHILIRFYTVKDAKTARKSVVSATWIIGIFYIMTVFLGFGAAAFVGFENILA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADKAGNMAAPLLAQALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKG
HCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AATEKEQMIAARWASIGVSVLSILLAVFAQSLNVAFLVSLAFAVAASANLPLIIFTVFWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RFNAAGALAGSLTGLLSALILVSISPSVWDPAGNAIFVGDPLIPLSNPGIISIPLGFLGA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHHHHH
YLGTILSSKTPGQDAFAEIQVKAHTGIHMDQS
HHHHHHCCCCCCCCCHHEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]