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The map label for this gene is xylB [H]

Identifier: 52787724

GI number: 52787724

Start: 3873063

End: 3874562

Strand: Reverse

Name: xylB [H]

Synonym: BLi04047

Alternate gene names: 52787724

Gene position: 3874562-3873063 (Counterclockwise)

Preceding gene: 52787725

Following gene: 52787718

Centisome position: 91.76

GC content: 52.4

Gene sequence:

>1500_bases
GTGGAATACGTAATCGGGGTCGATCTCGGCACCAGCACGGTTAAAATCATCCTTGTCAATCAGCGGGGAGAGCTGTGCGG
CGAGGTCTCCAAACCGTTTTCCATCATTGAGCCCCATTCCGGTTATTCCGAACAGGATCCCGCAGAATGGGCGGACAAAA
CGAAGGAAGCCATTAAGGAATTGGTCGGGCATTTCCCGGGAAAAGCATCTCAGATTAAAGGGGTCAGCTTTTCCGGACAG
ATGCATGGATTGGTACTTTTAAACGGCAAAGGAGAGGTTTTGCGAAACGCGATCCTGTGGAACGATACACGGACAACCGA
ACAATGCCGGCTGATTAACGACAAAATCGGAAAGGAGCGCCTGCTCGAGATCGCGAAAAATCCGGCGCTCGAAGGTTTTA
CCCTTCCGAAGCTTTTATGGGTGAAAGAATATGAAAAAGAGCTGTTTGAAAAGGCGGCCGTTTTTTTGCTGCCGAAAGAC
TATGTCAGGTACACCATGACGGGGCGTCTTCACAGCGAATATTCAGATGCGGCCGGAACGCTCCTGCTAGATGTGAGACA
TCAAACATGGAGCGGGGAAATCTGCAGAAAGCTCGGCATCCCGGAGTCCTTATGTCCGGATTTGATTGAACCGGGCGCTT
GTGTCGGCGGCCTCAGACCGGAATTCGCGGCCGAAACCGGGCTGTCTCCTGAAGTCAAGGTGTTTGCCGGCGGCGCTGAT
AATGCATGCGGCGCTGTCGGCGCCGGTATTTTAAAAGAAGGAACCGCCCTTTGCAGCATAGGCACCTCGGGGGTTGTTCT
CACATATGAATCAAACCGTGATCAAGAGTTTAATGGCAATATTCATTTTCTGAACCATGCAGCCCCCGATGCGTTTTATT
CGATGGGAGTGACGCTTTCTGCAGGACGCAGCTTCAGCTGGTTTAAAGATGTATTTGCCGGGCAGGCGTCATTTGACGAA
TTAATCAGCGATATTGGCCATTCCCGTCCCGGGGCCGGGGGACTGCTGTTTACCCCTTACTTGTCAGGGGAGAGAACTCC
TCATGCCGACGCAGATATTCGCGCCAGCTTCATCGGGATGGACAGCGCACATACACGGGCGGACTTTGTCAGAGCCGTTA
TTGAAGGCATTACATTCTCCCTTCATGAAAGCATTGAACAATTCCGTGCCGGGGGAAAAGACATCAGCCGTGTGATTTCA
ATCGGAGGAGGCGCCAAAAGCAATCAATGGCTGCAAATCCAGGCGGATATCTTCAACGCCGACATCATCAGACTGACAAG
CGAACAGGGGCCGGCATACGGTGCAGCCATGATCGCGGCCGTCGGGTGCGGCTGGTTTCCGTCGCTTGAGGCTTGTGCAG
ACCGATTCGTTCTCATCAAAGAAACCTTTTCGCCCCGCCGTGAATACAGCAGACAATACGAAGCTCTCTTTCAAATTTAC
AGAGATGTCTACCGGCACACGAAAACGCTGAACGAGCGGCTGGCAAGCTTTCGGGAATAA

Upstream 100 bases:

>100_bases
TTGAAAATCAGTCAGGCCGCCAAGAACGGCTGAAGGCGACCGTTAACCGTTACTTATTGAACGCTTTGCGCGAAGCGCCG
GCAGGAAAGGAGACACACTA

Downstream 100 bases:

>100_bases
ATAAAAACTTATGGGCCGGCCGGCTCATAAGTTTTTTTCGGCTGCACACGGTTTAAGATTGATCCATGTGGATGCCTGTA
TGCGCTTTGACCTGAATTTC

Product: hypothetical protein

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MEYVIGVDLGTSTVKIILVNQRGELCGEVSKPFSIIEPHSGYSEQDPAEWADKTKEAIKELVGHFPGKASQIKGVSFSGQ
MHGLVLLNGKGEVLRNAILWNDTRTTEQCRLINDKIGKERLLEIAKNPALEGFTLPKLLWVKEYEKELFEKAAVFLLPKD
YVRYTMTGRLHSEYSDAAGTLLLDVRHQTWSGEICRKLGIPESLCPDLIEPGACVGGLRPEFAAETGLSPEVKVFAGGAD
NACGAVGAGILKEGTALCSIGTSGVVLTYESNRDQEFNGNIHFLNHAAPDAFYSMGVTLSAGRSFSWFKDVFAGQASFDE
LISDIGHSRPGAGGLLFTPYLSGERTPHADADIRASFIGMDSAHTRADFVRAVIEGITFSLHESIEQFRAGGKDISRVIS
IGGGAKSNQWLQIQADIFNADIIRLTSEQGPAYGAAMIAAVGCGWFPSLEACADRFVLIKETFSPRREYSRQYEALFQIY
RDVYRHTKTLNERLASFRE

Sequences:

>Translated_499_residues
MEYVIGVDLGTSTVKIILVNQRGELCGEVSKPFSIIEPHSGYSEQDPAEWADKTKEAIKELVGHFPGKASQIKGVSFSGQ
MHGLVLLNGKGEVLRNAILWNDTRTTEQCRLINDKIGKERLLEIAKNPALEGFTLPKLLWVKEYEKELFEKAAVFLLPKD
YVRYTMTGRLHSEYSDAAGTLLLDVRHQTWSGEICRKLGIPESLCPDLIEPGACVGGLRPEFAAETGLSPEVKVFAGGAD
NACGAVGAGILKEGTALCSIGTSGVVLTYESNRDQEFNGNIHFLNHAAPDAFYSMGVTLSAGRSFSWFKDVFAGQASFDE
LISDIGHSRPGAGGLLFTPYLSGERTPHADADIRASFIGMDSAHTRADFVRAVIEGITFSLHESIEQFRAGGKDISRVIS
IGGGAKSNQWLQIQADIFNADIIRLTSEQGPAYGAAMIAAVGCGWFPSLEACADRFVLIKETFSPRREYSRQYEALFQIY
RDVYRHTKTLNERLASFRE
>Mature_499_residues
MEYVIGVDLGTSTVKIILVNQRGELCGEVSKPFSIIEPHSGYSEQDPAEWADKTKEAIKELVGHFPGKASQIKGVSFSGQ
MHGLVLLNGKGEVLRNAILWNDTRTTEQCRLINDKIGKERLLEIAKNPALEGFTLPKLLWVKEYEKELFEKAAVFLLPKD
YVRYTMTGRLHSEYSDAAGTLLLDVRHQTWSGEICRKLGIPESLCPDLIEPGACVGGLRPEFAAETGLSPEVKVFAGGAD
NACGAVGAGILKEGTALCSIGTSGVVLTYESNRDQEFNGNIHFLNHAAPDAFYSMGVTLSAGRSFSWFKDVFAGQASFDE
LISDIGHSRPGAGGLLFTPYLSGERTPHADADIRASFIGMDSAHTRADFVRAVIEGITFSLHESIEQFRAGGKDISRVIS
IGGGAKSNQWLQIQADIFNADIIRLTSEQGPAYGAAMIAAVGCGWFPSLEACADRFVLIKETFSPRREYSRQYEALFQIY
RDVYRHTKTLNERLASFRE

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=546, Percent_Identity=23.6263736263736, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI42794763, Length=449, Percent_Identity=23.8307349665924, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI88196792, Length=483, Percent_Identity=23.6024844720497, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI164663830, Length=570, Percent_Identity=22.4561403508772, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI189409120, Length=449, Percent_Identity=23.8307349665924, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4504007, Length=449, Percent_Identity=23.8307349665924, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI41393575, Length=442, Percent_Identity=24.4343891402715, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI18860918, Length=398, Percent_Identity=22.8643216080402, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789987, Length=486, Percent_Identity=36.6255144032922, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI1790005, Length=497, Percent_Identity=27.364185110664, Blast_Score=168, Evalue=9e-43,
Organism=Escherichia coli, GI1789168, Length=481, Percent_Identity=25.7796257796258, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789138, Length=514, Percent_Identity=22.568093385214, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1790361, Length=483, Percent_Identity=22.360248447205, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787789, Length=513, Percent_Identity=23.1968810916179, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1786249, Length=566, Percent_Identity=22.0848056537102, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17535599, Length=449, Percent_Identity=23.8307349665924, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321755, Length=416, Percent_Identity=24.5192307692308, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320314, Length=523, Percent_Identity=21.7973231357553, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864214, Length=472, Percent_Identity=23.0932203389831, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24655555, Length=490, Percent_Identity=23.0612244897959, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24655560, Length=490, Percent_Identity=23.0612244897959, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24655570, Length=490, Percent_Identity=23.0612244897959, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24655574, Length=490, Percent_Identity=23.0612244897959, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24655565, Length=490, Percent_Identity=23.0612244897959, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21357867, Length=515, Percent_Identity=21.9417475728155, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24654573, Length=412, Percent_Identity=23.0582524271845, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656367, Length=498, Percent_Identity=22.0883534136546, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24657106, Length=550, Percent_Identity=23.4545454545455, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24657102, Length=550, Percent_Identity=23.4545454545455, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356607, Length=554, Percent_Identity=22.2021660649819, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24656372, Length=407, Percent_Identity=22.3587223587224, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54706; Mature: 54706

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVIGVDLGTSTVKIILVNQRGELCGEVSKPFSIIEPHSGYSEQDPAEWADKTKEAIKE
CCEEEEEECCCCEEEEEEECCCCHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
LVGHFPGKASQIKGVSFSGQMHGLVLLNGKGEVLRNAILWNDTRTTEQCRLINDKIGKER
HHHHCCCCCHHCCCCEECCCEEEEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHCCHHH
LLEIAKNPALEGFTLPKLLWVKEYEKELFEKAAVFLLPKDYVRYTMTGRLHSEYSDAAGT
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECHHHHEEEEECCHHHHHHHCCCE
LLLDVRHQTWSGEICRKLGIPESLCPDLIEPGACVGGLRPEFAAETGLSPEVKVFAGGAD
EEEEECCCCCCHHHHHHCCCCHHHCHHHCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCC
NACGAVGAGILKEGTALCSIGTSGVVLTYESNRDQEFNGNIHFLNHAAPDAFYSMGVTLS
CCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHCCEEEE
AGRSFSWFKDVFAGQASFDELISDIGHSRPGAGGLLFTPYLSGERTPHADADIRASFIGM
CCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECC
DSAHTRADFVRAVIEGITFSLHESIEQFRAGGKDISRVISIGGGAKSNQWLQIQADIFNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEEECCC
DIIRLTSEQGPAYGAAMIAAVGCGWFPSLEACADRFVLIKETFSPRREYSRQYEALFQIY
EEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHCCEEEEEHHCCHHHHHHHHHHHHHHHH
RDVYRHTKTLNERLASFRE
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYVIGVDLGTSTVKIILVNQRGELCGEVSKPFSIIEPHSGYSEQDPAEWADKTKEAIKE
CCEEEEEECCCCEEEEEEECCCCHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
LVGHFPGKASQIKGVSFSGQMHGLVLLNGKGEVLRNAILWNDTRTTEQCRLINDKIGKER
HHHHCCCCCHHCCCCEECCCEEEEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHCCHHH
LLEIAKNPALEGFTLPKLLWVKEYEKELFEKAAVFLLPKDYVRYTMTGRLHSEYSDAAGT
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECHHHHEEEEECCHHHHHHHCCCE
LLLDVRHQTWSGEICRKLGIPESLCPDLIEPGACVGGLRPEFAAETGLSPEVKVFAGGAD
EEEEECCCCCCHHHHHHCCCCHHHCHHHCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCC
NACGAVGAGILKEGTALCSIGTSGVVLTYESNRDQEFNGNIHFLNHAAPDAFYSMGVTLS
CCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHCCEEEE
AGRSFSWFKDVFAGQASFDELISDIGHSRPGAGGLLFTPYLSGERTPHADADIRASFIGM
CCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECC
DSAHTRADFVRAVIEGITFSLHESIEQFRAGGKDISRVISIGGGAKSNQWLQIQADIFNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEEECCC
DIIRLTSEQGPAYGAAMIAAVGCGWFPSLEACADRFVLIKETFSPRREYSRQYEALFQIY
EEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHCCEEEEEHHCCHHHHHHHHHHHHHHHH
RDVYRHTKTLNERLASFRE
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]