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The map label for this gene is galE [H]

Identifier: 52787718

GI number: 52787718

Start: 3867940

End: 3868929

Strand: Reverse

Name: galE [H]

Synonym: BLi04041

Alternate gene names: 52787718

Gene position: 3868929-3867940 (Counterclockwise)

Preceding gene: 52787724

Following gene: 52787717

Centisome position: 91.62

GC content: 50.2

Gene sequence:

>990_bases
TTGGCAATATTAGTATGCGGAGGGGCGGGCTATATTGGAAGCCATGCTGTAGCGGAACTGTTAAGCCGCAATGAAGATGT
CGTAATTATTGATAACCTGCAAACTGGACATGAAGAGGCGGCTTTAAAGGGAGCTTCTTTCTATAATGGAGATCTGCGCG
ATGAAGCATTTCTAAGAAAGGTGTTTCAGGAAAACGACATTGAGGCTGTCATGCATTTCGCGGCCGATTCATTGGTTGGA
GAAAGCGTAACAGATCCTCTCAAATATTATGACAACAACGTTTACGGAGCTGTTTGCCTGTTAAAGGTCATGAAAGAGTT
CGATGTGAAGCAAATTGTTTTCTCATCAACCGCTGCAACATACGGAGAACCGGATCGGGTGCCGATTATGGAAACAGATC
CGACGGATCCGACAAACCCGTACGGGGAAACGAAGCTTGCAATTGAAAAAATGCTGAAGTGGTCTGAAAAGGCATACGGA
ATCCGTCATGTCGTCCTTCGCTACTTTAATGTTGCCGGGGCGCATGTAGACGGCTTGATCGGCGAGGACCACCAGCCTGA
AACGCACCTGATTCCGATCATTCTTCAAGTCGCGCTAGGCAAACGGGACAAGATTATGATTTTCGGCGACGACTATCCGA
CTCCGGATGGCACGTGCATCAGAGACTACATCCATGTGATGGATCTGGTCGACGCGCATATTCTCGCTGTCGAGAGGCTT
CGAAACGGCGGAGAAAGCGCCGTATACAATCTCGGAAACGGAACGGGCTTCTCAGTCAAAGAAGTCGTTGAAACTGCCCG
GAAAGTGACAGGCTGTCCGATACCGGCGGAGGTTGCAGAGCGCCGCGCAGGAGACCCGGCACAGCTGATCGCCTCTTCGG
AAAAAGCGGTGAAAGAGCTTGGATGGCAGCCGAAGTACGCCGAACTGGAAACGATCATTGACAGCGCGTGGAAGTGGTTT
AAAGCACATCCGAACGGCTATCAAAGCTAG

Upstream 100 bases:

>100_bases
GAAAAAAGCAAATATATCATCTTTGTTTGAAAAAGAGATTCACAGGCGTTTTATAGATTTTAAAATAGAAGGATAACGCC
GCTGAAAGGAGAGAAATGAA

Downstream 100 bases:

>100_bases
AATGCGATAACGCCTATTATATAGGATAAAAAAGAGCTTTCAGTCACAGAAGAAAGCTCTTTTTTGATGTTCTTTAGTTT
AAAACCGGTTGTCAGCAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAILVCGGAGYIGSHAVAELLSRNEDVVIIDNLQTGHEEAALKGASFYNGDLRDEAFLRKVFQENDIEAVMHFAADSLVG
ESVTDPLKYYDNNVYGAVCLLKVMKEFDVKQIVFSSTAATYGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYG
IRHVVLRYFNVAGAHVDGLIGEDHQPETHLIPIILQVALGKRDKIMIFGDDYPTPDGTCIRDYIHVMDLVDAHILAVERL
RNGGESAVYNLGNGTGFSVKEVVETARKVTGCPIPAEVAERRAGDPAQLIASSEKAVKELGWQPKYAELETIIDSAWKWF
KAHPNGYQS

Sequences:

>Translated_329_residues
MAILVCGGAGYIGSHAVAELLSRNEDVVIIDNLQTGHEEAALKGASFYNGDLRDEAFLRKVFQENDIEAVMHFAADSLVG
ESVTDPLKYYDNNVYGAVCLLKVMKEFDVKQIVFSSTAATYGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYG
IRHVVLRYFNVAGAHVDGLIGEDHQPETHLIPIILQVALGKRDKIMIFGDDYPTPDGTCIRDYIHVMDLVDAHILAVERL
RNGGESAVYNLGNGTGFSVKEVVETARKVTGCPIPAEVAERRAGDPAQLIASSEKAVKELGWQPKYAELETIIDSAWKWF
KAHPNGYQS
>Mature_328_residues
AILVCGGAGYIGSHAVAELLSRNEDVVIIDNLQTGHEEAALKGASFYNGDLRDEAFLRKVFQENDIEAVMHFAADSLVGE
SVTDPLKYYDNNVYGAVCLLKVMKEFDVKQIVFSSTAATYGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYGI
RHVVLRYFNVAGAHVDGLIGEDHQPETHLIPIILQVALGKRDKIMIFGDDYPTPDGTCIRDYIHVMDLVDAHILAVERLR
NGGESAVYNLGNGTGFSVKEVVETARKVTGCPIPAEVAERRAGDPAQLIASSEKAVKELGWQPKYAELETIIDSAWKWFK
AHPNGYQS

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=41.6909620991254, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=41.6909620991254, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=41.6909620991254, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI7657641, Length=345, Percent_Identity=26.6666666666667, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI42516563, Length=327, Percent_Identity=24.7706422018349, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=43.9169139465875, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1788353, Length=354, Percent_Identity=27.4011299435028, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994969, Length=357, Percent_Identity=27.1708683473389, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790049, Length=290, Percent_Identity=26.551724137931, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=41.3793103448276, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=41.1428571428571, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17568069, Length=327, Percent_Identity=28.1345565749235, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539532, Length=310, Percent_Identity=25.4838709677419, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=25.8461538461538, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=44.1860465116279, Blast_Score=271, Evalue=7e-74,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=41.7391304347826, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI21356223, Length=327, Percent_Identity=26.2996941896024, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36287; Mature: 36155

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVCGGAGYIGSHAVAELLSRNEDVVIIDNLQTGHEEAALKGASFYNGDLRDEAFLRK
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCHHHHHHHH
VFQENDIEAVMHFAADSLVGESVTDPLKYYDNNVYGAVCLLKVMKEFDVKQIVFSSTAAT
HHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
YGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYGIRHVVLRYFNVAGAHVDGLI
CCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
GEDHQPETHLIPIILQVALGKRDKIMIFGDDYPTPDGTCIRDYIHVMDLVDAHILAVERL
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RNGGESAVYNLGNGTGFSVKEVVETARKVTGCPIPAEVAERRAGDPAQLIASSEKAVKEL
HCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHC
GWQPKYAELETIIDSAWKWFKAHPNGYQS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AILVCGGAGYIGSHAVAELLSRNEDVVIIDNLQTGHEEAALKGASFYNGDLRDEAFLRK
EEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCCCHHHHHHHH
VFQENDIEAVMHFAADSLVGESVTDPLKYYDNNVYGAVCLLKVMKEFDVKQIVFSSTAAT
HHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
YGEPDRVPIMETDPTDPTNPYGETKLAIEKMLKWSEKAYGIRHVVLRYFNVAGAHVDGLI
CCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
GEDHQPETHLIPIILQVALGKRDKIMIFGDDYPTPDGTCIRDYIHVMDLVDAHILAVERL
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RNGGESAVYNLGNGTGFSVKEVVETARKVTGCPIPAEVAERRAGDPAQLIASSEKAVKEL
HCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHC
GWQPKYAELETIIDSAWKWFKAHPNGYQS
CCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]