Click here to switch to the map view.

The map label for this gene is acdA [H]

Identifier: 52787643

GI number: 52787643

Start: 3790154

End: 3791293

Strand: Reverse

Name: acdA [H]

Synonym: BLi03965

Alternate gene names: 52787643

Gene position: 3791293-3790154 (Counterclockwise)

Preceding gene: 52787644

Following gene: 52787642

Centisome position: 89.78

GC content: 52.11

Gene sequence:

>1140_bases
ATGATCTTTAAGCTGAGCGAAGAGCACCAAATGATACAGAAGATGGTGCGCGACTTTGCCCATCACGAGGTGGAGCCGAC
TGCGAAAGAGCGGGATGAGGAAGAGCGGTTTGACATGGAACTGTTTGCAAAAATGGCGGAATTGGGGCTCACGGGTATAC
CGTGGCCAGAGGAATACGGGGGAATCGGCAGCGACTATCTCGCCTACGTCATCGCGGTTGAAGAGCTTTCGAAAGTCTGC
GCCTCAACGGGTGTCACCTTGTCTGCCCATACATCGCTTGCGGGCTGGCCGATTTATGCATTTGGAACAGAAGAACAGAA
ACAGGAATATTTAAAGCCGATGGCCCGCGGCGAAAAGATAGGAGCCTACGGATTGACGGAGCCCGGTTCAGGCTCCGATG
CCGGCGGCATGAAAACGACCGCAGAAAAAAAAGGCGATGAATATATTTTGAACGGGACGAAGATCTTTATCACAAACGGC
GGAATCGCGGACTTCTACATCGTGTTTGCCAACCTTGCCCCGGAACAGAAACACAAAGGCACAACCGCCTTTATCGTTGA
AAAGGACTTCCCCGGCTTTTCTGTCGGAAAAAAAGAGAGGAAACTGGGCATCCGTTCATCACCGACAACCGAAATCATCT
TTCAGGACTGCCGCGTGCCTTTAAAAAACCGCCTTGGCGGGGAAGGTGAAGGCTTTAAAATCGCGATGAAGACGCTCGAT
GGAGGCAGAAACGGAATTGCCGCTCAAGCCGTCGGGATTGCCCAGGGCGCATTTGAGGCGGCGAAGGCGTATGCGAAAGA
GCGGAAGCAATTCGGCAGGCCGATCGCCGAGCAGCAGGGCATCGCTTTTAAACTGGCTGATATGGCGACGGAGATTGAAG
CTTCAAGGCTTTTAACCTACCAGGCGGCATGGCTGGAATCAGAAGGACTGCCTTATGGAAAGGCTTCTGCCATGTCAAAG
CTTTACGCAGGGGATACGGCCATGAAAGTGACGACGGAGGCCGTGCAAATATTCGGCGGGTACGGCTACACAAAGGATTA
TCCGGTCGAGCGCTTTATGCGCGATGCAAAAATCACACAGATCTATGAAGGTACGCAGGAAATTCAGAAGCTCGTCATTT
CGAGAATGCTGATGAAATAA

Upstream 100 bases:

>100_bases
TTTCAGGGATGCGAAAGTGTGTGAAATTTATGAGGGCACGAGCGAGATCCAGCGGATCGTCATCGGTAAACATTTATAAG
GTGTCAAAGGGGGAAAAAGG

Downstream 100 bases:

>100_bases
GGGTGGAAAATCGCCGTCTGGCCCGGCTTGATCTGCCGCCGGCGGACAGGATGCCGGCGCAGTTTTTTTGTTTTGAAGGG
GCCGGACGCTCCCGGCTGTT

Product: AcdA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MIFKLSEEHQMIQKMVRDFAHHEVEPTAKERDEEERFDMELFAKMAELGLTGIPWPEEYGGIGSDYLAYVIAVEELSKVC
ASTGVTLSAHTSLAGWPIYAFGTEEQKQEYLKPMARGEKIGAYGLTEPGSGSDAGGMKTTAEKKGDEYILNGTKIFITNG
GIADFYIVFANLAPEQKHKGTTAFIVEKDFPGFSVGKKERKLGIRSSPTTEIIFQDCRVPLKNRLGGEGEGFKIAMKTLD
GGRNGIAAQAVGIAQGAFEAAKAYAKERKQFGRPIAEQQGIAFKLADMATEIEASRLLTYQAAWLESEGLPYGKASAMSK
LYAGDTAMKVTTEAVQIFGGYGYTKDYPVERFMRDAKITQIYEGTQEIQKLVISRMLMK

Sequences:

>Translated_379_residues
MIFKLSEEHQMIQKMVRDFAHHEVEPTAKERDEEERFDMELFAKMAELGLTGIPWPEEYGGIGSDYLAYVIAVEELSKVC
ASTGVTLSAHTSLAGWPIYAFGTEEQKQEYLKPMARGEKIGAYGLTEPGSGSDAGGMKTTAEKKGDEYILNGTKIFITNG
GIADFYIVFANLAPEQKHKGTTAFIVEKDFPGFSVGKKERKLGIRSSPTTEIIFQDCRVPLKNRLGGEGEGFKIAMKTLD
GGRNGIAAQAVGIAQGAFEAAKAYAKERKQFGRPIAEQQGIAFKLADMATEIEASRLLTYQAAWLESEGLPYGKASAMSK
LYAGDTAMKVTTEAVQIFGGYGYTKDYPVERFMRDAKITQIYEGTQEIQKLVISRMLMK
>Mature_379_residues
MIFKLSEEHQMIQKMVRDFAHHEVEPTAKERDEEERFDMELFAKMAELGLTGIPWPEEYGGIGSDYLAYVIAVEELSKVC
ASTGVTLSAHTSLAGWPIYAFGTEEQKQEYLKPMARGEKIGAYGLTEPGSGSDAGGMKTTAEKKGDEYILNGTKIFITNG
GIADFYIVFANLAPEQKHKGTTAFIVEKDFPGFSVGKKERKLGIRSSPTTEIIFQDCRVPLKNRLGGEGEGFKIAMKTLD
GGRNGIAAQAVGIAQGAFEAAKAYAKERKQFGRPIAEQQGIAFKLADMATEIEASRLLTYQAAWLESEGLPYGKASAMSK
LYAGDTAMKVTTEAVQIFGGYGYTKDYPVERFMRDAKITQIYEGTQEIQKLVISRMLMK

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=50.7978723404255, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=42.627345844504, Blast_Score=312, Evalue=4e-85,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=41.7553191489362, Blast_Score=311, Evalue=5e-85,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=44.2970822281167, Blast_Score=307, Evalue=9e-84,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=44.2970822281167, Blast_Score=307, Evalue=1e-83,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=40.7407407407407, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI226958414, Length=354, Percent_Identity=41.5254237288136, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI21361497, Length=379, Percent_Identity=40.1055408970976, Blast_Score=251, Evalue=7e-67,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=35.978835978836, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI76496475, Length=378, Percent_Identity=37.5661375661376, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI4557235, Length=378, Percent_Identity=37.5661375661376, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=32.7127659574468, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI7669494, Length=365, Percent_Identity=32.6027397260274, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI48976061, Length=291, Percent_Identity=30.5841924398625, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI211971008, Length=291, Percent_Identity=30.5841924398625, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI38505218, Length=295, Percent_Identity=28.135593220339, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI218563752, Length=271, Percent_Identity=25.4612546125461, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=31.9371727748691, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=30.1837270341207, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI87082384, Length=276, Percent_Identity=29.3478260869565, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081702, Length=328, Percent_Identity=28.0487804878049, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=43.5828877005348, Blast_Score=317, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=46.0526315789474, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=43.0446194225722, Blast_Score=306, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=45.1697127937337, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=40.7506702412869, Blast_Score=298, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=39.7368421052632, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI17533517, Length=364, Percent_Identity=40.9340659340659, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=45.4873646209386, Blast_Score=244, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI71985184, Length=360, Percent_Identity=36.3888888888889, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=33.5106382978723, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=39.1791044776119, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=42.6086956521739, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=380, Percent_Identity=30.5263157894737, Blast_Score=187, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=30.2139037433155, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=38.2456140350877, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=35.2697095435685, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17562446, Length=288, Percent_Identity=29.8611111111111, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=31.25, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI86563381, Length=274, Percent_Identity=27.007299270073, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=274, Percent_Identity=27.007299270073, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=51.4666666666667, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=47.7333333333333, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=44.7089947089947, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=42.1333333333333, Blast_Score=314, Evalue=5e-86,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=41.6230366492147, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI281363737, Length=360, Percent_Identity=38.3333333333333, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=34.3915343915344, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI45550141, Length=313, Percent_Identity=27.4760383386581, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221473076, Length=313, Percent_Identity=27.4760383386581, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41742; Mature: 41742

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKLSEEHQMIQKMVRDFAHHEVEPTAKERDEEERFDMELFAKMAELGLTGIPWPEEYG
CEEEECHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHC
GIGSDYLAYVIAVEELSKVCASTGVTLSAHTSLAGWPIYAFGTEEQKQEYLKPMARGEKI
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHCCCCC
GAYGLTEPGSGSDAGGMKTTAEKKGDEYILNGTKIFITNGGIADFYIVFANLAPEQKHKG
CCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCEEEEEECCCCCEEEEEEECCCCCHHCCC
TTAFIVEKDFPGFSVGKKERKLGIRSSPTTEIIFQDCRVPLKNRLGGEGEGFKIAMKTLD
CEEEEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHCCCCCCCCEEEEEEECC
GGRNGIAAQAVGIAQGAFEAAKAYAKERKQFGRPIAEQQGIAFKLADMATEIEASRLLTY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHHHHHHHHH
QAAWLESEGLPYGKASAMSKLYAGDTAMKVTTEAVQIFGGYGYTKDYPVERFMRDAKITQ
HHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IYEGTQEIQKLVISRMLMK
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFKLSEEHQMIQKMVRDFAHHEVEPTAKERDEEERFDMELFAKMAELGLTGIPWPEEYG
CEEEECHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHC
GIGSDYLAYVIAVEELSKVCASTGVTLSAHTSLAGWPIYAFGTEEQKQEYLKPMARGEKI
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHCCCCC
GAYGLTEPGSGSDAGGMKTTAEKKGDEYILNGTKIFITNGGIADFYIVFANLAPEQKHKG
CCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCEEEEEECCCCCEEEEEEECCCCCHHCCC
TTAFIVEKDFPGFSVGKKERKLGIRSSPTTEIIFQDCRVPLKNRLGGEGEGFKIAMKTLD
CEEEEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHCCCCHHHCCCCCCCCEEEEEEECC
GGRNGIAAQAVGIAQGAFEAAKAYAKERKQFGRPIAEQQGIAFKLADMATEIEASRLLTY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEHHHHHHHHHHHHHHHH
QAAWLESEGLPYGKASAMSKLYAGDTAMKVTTEAVQIFGGYGYTKDYPVERFMRDAKITQ
HHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
IYEGTQEIQKLVISRMLMK
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]