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The map label for this gene is rpoE

Identifier: 52787642

GI number: 52787642

Start: 3789337

End: 3789852

Strand: Reverse

Name: rpoE

Synonym: BLi03964

Alternate gene names: 52787642

Gene position: 3789852-3789337 (Counterclockwise)

Preceding gene: 52787643

Following gene: 52787641

Centisome position: 89.75

GC content: 43.41

Gene sequence:

>516_bases
ATGAGTTTGAAACAATACTCAGAGGAACAGCTAAAGGAAATGGCTTTAGTTGAAATCGCATACGAAATTTTCTCGGAACA
CAAAAAACCGATTACATTCCAGGAGCTAACAGATCAAGTGGCTTCCTTGCTTGGAATGGGGAAAGAAGAGCTGGAAGACC
GCATCGCCCAGTTCTACACAGATTTAAATATCGACGGACGCTTTTTGGCGCTGTCAGACCAAACGTGGGGCCTGCGCAGC
TGGTATCCGTATGATCAGCTTGATGAAGAAACCCAGCCGACTGTAAAAGCGAAAAAGAAAAAAGCGAAAAAAGCGGTTGA
AGAAGATCTTGATCTTGACGAATTCGAAGAAATCGACGAGGATGATATTCTTCTTGACGATGTCGAAGAAGATTTGGACA
TTGACGCCGATGAATTCGATGAAATCGATGAAGCCGACGATGATGAGCTGGATGATCTTGAAGACGAGATCCTGGATGAT
GATGAAGATTTTGATGAAGAGGAAGACGAAGAGTAA

Upstream 100 bases:

>100_bases
ATGAGAGGTATGGTTTGTCGTAAAGACAGGGATTACATGCTTATTTTCTATGACAGAGATAGTAGATACATACATGAAGA
TAGAAAGGGAGTGTCTGGCG

Downstream 100 bases:

>100_bases
TTGCCTTCTGAACGGAATTCATGTTTAAATCGATCTTGACTTTCACAGGCGAACTAGGTAGTATGTATTTTGGGCTCTTC
AAAACGAAGAGATTCGAGTG

Product: DNA-directed RNA polymerase subunit delta

Products: diphosphate; RNAn+1

Alternate protein names: RNAP delta factor

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSLKQYSEEQLKEMALVEIAYEIFSEHKKPITFQELTDQVASLLGMGKEELEDRIAQFYTDLNIDGRFLALSDQTWGLRS
WYPYDQLDEETQPTVKAKKKKAKKAVEEDLDLDEFEEIDEDDILLDDVEEDLDIDADEFDEIDEADDDELDDLEDEILDD
DEDFDEEEDEE

Sequences:

>Translated_171_residues
MSLKQYSEEQLKEMALVEIAYEIFSEHKKPITFQELTDQVASLLGMGKEELEDRIAQFYTDLNIDGRFLALSDQTWGLRS
WYPYDQLDEETQPTVKAKKKKAKKAVEEDLDLDEFEEIDEDDILLDDVEEDLDIDADEFDEIDEADDDELDDLEDEILDD
DEDFDEEEDEE
>Mature_170_residues
SLKQYSEEQLKEMALVEIAYEIFSEHKKPITFQELTDQVASLLGMGKEELEDRIAQFYTDLNIDGRFLALSDQTWGLRSW
YPYDQLDEETQPTVKAKKKKAKKAVEEDLDLDEFEEIDEDDILLDDVEEDLDIDADEFDEIDEADDDELDDLEDEILDDD
EDFDEEEDEE

Specific function: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis

COG id: COG3343

COG function: function code K; DNA-directed RNA polymerase, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rpoE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOE_BACLD (Q65DT6)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_081041.1
- RefSeq:   YP_093471.1
- STRING:   Q65DT6
- EnsemblBacteria:   EBBACT00000056991
- EnsemblBacteria:   EBBACT00000061545
- GeneID:   3028496
- GeneID:   3101372
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03964
- KEGG:   bli:BL05358
- NMPDR:   fig|279010.5.peg.2899
- eggNOG:   COG3343
- GeneTree:   EBGT00050000000191
- OMA:   TDMNTDG
- ProtClustDB:   PRK02363
- BioCyc:   BLIC279010-1:BLI03964-MONOMER
- BioCyc:   BLIC279010:BL05358-MONOMER
- HAMAP:   MF_00357
- InterPro:   IPR007759
- PANTHER:   PTHR23405:SF1

Pfam domain/function: PF05066 RNA_pol_delta

EC number: 2.7.7.6

Molecular weight: Translated: 20093; Mature: 19961

Theoretical pI: Translated: 3.53; Mature: 3.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKQYSEEQLKEMALVEIAYEIFSEHKKPITFQELTDQVASLLGMGKEELEDRIAQFYT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DLNIDGRFLALSDQTWGLRSWYPYDQLDEETQPTVKAKKKKAKKAVEEDLDLDEFEEIDE
CCCCCCEEEEECCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
DDILLDDVEEDLDIDADEFDEIDEADDDELDDLEDEILDDDEDFDEEEDEE
CCCCHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLKQYSEEQLKEMALVEIAYEIFSEHKKPITFQELTDQVASLLGMGKEELEDRIAQFYT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DLNIDGRFLALSDQTWGLRSWYPYDQLDEETQPTVKAKKKKAKKAVEEDLDLDEFEEIDE
CCCCCCEEEEECCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCC
DDILLDDVEEDLDIDADEFDEIDEADDDELDDLEDEILDDDEDFDEEEDEE
CCCCHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside triphosphate; RNAn

Specific reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA