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The map label for this gene is fhuG [H]

Identifier: 52787211

GI number: 52787211

Start: 3362016

End: 3363029

Strand: Reverse

Name: fhuG [H]

Synonym: BLi03520

Alternate gene names: 52787211

Gene position: 3363029-3362016 (Counterclockwise)

Preceding gene: 52787212

Following gene: 52787210

Centisome position: 79.64

GC content: 52.07

Gene sequence:

>1014_bases
ATGCTCAAGAAAAACAACAGACGGGCGGGTGCGGTGATGCTCGTCATGGCCGTGCTGACGGCCGCCGTGTTTTTATTAAG
CATGAACATGGGAGAAATCCGCATCGACCCGCTTGCTACATTGAGAACACTGTTCGGCTTTGGAACGCCGCAGGATGAAC
TTGTATTATTTGAATTCCGTCTGCCGCGCATGATCCTCGCCATGCTGATCGGTGCAGGGGTTGCTGTCTCCGGAGCCGTC
TGGCAGGGGATATCCCGGAATGACCTGGCCGATCCGGGGATATTGGGCATCAATACGGGAGCGGGTTTTGCCGTTGTGCT
GTTCATCTTCTATTTTCAGGGAGACGTTGGCAACCTGCAAAAAGGATTCGTTTTTTCCCTGCCGATATTCGCATTTTTGG
GAGCCTGCTTTGCAGTCGTTTCCATCTATTTGCTGGCGTGGAAAAAAGGCTTGAATCCCATTCGCCTCGTTTTGGTCGGC
ATCGGAGTGAATGCGGCGTTTTCGGCGGCCATCTTAATGCTGCAGCTTAAAATGGACCCAAATGACTTTATGCAGGCGGC
TGTTTGGCTGTCAGGGAATATATGGAGTTCGAACTGGAGCTTTGTCTCGGCCGTGCTGCCCTGGATTGTCGTGCTGATTC
CTTTTATCCTCTATAAAGCGCGCTATTTAAACGTGCTGAATCTCGGTGATCAGCTCGCAACAGGGCTCGGAACGGCAGTT
GAAAAAGAGCGGCGCACACTGCTTCTGTCGGCAGCCGCGCTGAGCGGCGCGTGTGTAGCGGCTGGAGGAAACATTACGTT
TCTCGGTCTCGTGGCTCCGCATATTGCCAGAAGACTTGTCGGGCCGAAGCATCAGCTTTTAATCCCGGCTTCCGCGTTGA
CCGGAGCATTGCTCTTTTTGCTGGCGGACTTAATTGGAAGAATGATACTGGCGCCTTCGGAAATTCCCGTAGGGCTTGTC
ATTGCCGCTTTAGGCGCACCGTATTTTATCTATTTGCTTATGAAAACAAATTAA

Upstream 100 bases:

>100_bases
TGGTCAACCCGCCGTTTGAAACACCTGTCGGAGCAGTAACTGCGCTTGTCGGCGTACCATTCTTTCTCTATCTGGCCCGC
AGGGAAAGGAGTGGACTGTA

Downstream 100 bases:

>100_bases
AGAAGGGAAGGGTGCAACGTGTCTCTTTCAACAAACAACCTGGGGATCGGCTACGGCGAACAGATGATTGTCGAAAACTT
AAACCTCCACATACCAAAAG

Product: FhuG

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLKKNNRRAGAVMLVMAVLTAAVFLLSMNMGEIRIDPLATLRTLFGFGTPQDELVLFEFRLPRMILAMLIGAGVAVSGAV
WQGISRNDLADPGILGINTGAGFAVVLFIFYFQGDVGNLQKGFVFSLPIFAFLGACFAVVSIYLLAWKKGLNPIRLVLVG
IGVNAAFSAAILMLQLKMDPNDFMQAAVWLSGNIWSSNWSFVSAVLPWIVVLIPFILYKARYLNVLNLGDQLATGLGTAV
EKERRTLLLSAAALSGACVAAGGNITFLGLVAPHIARRLVGPKHQLLIPASALTGALLFLLADLIGRMILAPSEIPVGLV
IAALGAPYFIYLLMKTN

Sequences:

>Translated_337_residues
MLKKNNRRAGAVMLVMAVLTAAVFLLSMNMGEIRIDPLATLRTLFGFGTPQDELVLFEFRLPRMILAMLIGAGVAVSGAV
WQGISRNDLADPGILGINTGAGFAVVLFIFYFQGDVGNLQKGFVFSLPIFAFLGACFAVVSIYLLAWKKGLNPIRLVLVG
IGVNAAFSAAILMLQLKMDPNDFMQAAVWLSGNIWSSNWSFVSAVLPWIVVLIPFILYKARYLNVLNLGDQLATGLGTAV
EKERRTLLLSAAALSGACVAAGGNITFLGLVAPHIARRLVGPKHQLLIPASALTGALLFLLADLIGRMILAPSEIPVGLV
IAALGAPYFIYLLMKTN
>Mature_337_residues
MLKKNNRRAGAVMLVMAVLTAAVFLLSMNMGEIRIDPLATLRTLFGFGTPQDELVLFEFRLPRMILAMLIGAGVAVSGAV
WQGISRNDLADPGILGINTGAGFAVVLFIFYFQGDVGNLQKGFVFSLPIFAFLGACFAVVSIYLLAWKKGLNPIRLVLVG
IGVNAAFSAAILMLQLKMDPNDFMQAAVWLSGNIWSSNWSFVSAVLPWIVVLIPFILYKARYLNVLNLGDQLATGLGTAV
EKERRTLLLSAAALSGACVAAGGNITFLGLVAPHIARRLVGPKHQLLIPASALTGALLFLLADLIGRMILAPSEIPVGLV
IAALGAPYFIYLLMKTN

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=315, Percent_Identity=40.6349206349206, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1786804, Length=327, Percent_Identity=31.4984709480122, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1786347, Length=338, Percent_Identity=34.9112426035503, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=35.6401384083045, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786805, Length=294, Percent_Identity=34.6938775510204, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790741, Length=300, Percent_Identity=32.6666666666667, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36074; Mature: 36074

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKNNRRAGAVMLVMAVLTAAVFLLSMNMGEIRIDPLATLRTLFGFGTPQDELVLFEFR
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCCCCEEEEEEH
LPRMILAMLIGAGVAVSGAVWQGISRNDLADPGILGINTGAGFAVVLFIFYFQGDVGNLQ
HHHHHHHHHHHCCHHCCHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC
KGFVFSLPIFAFLGACFAVVSIYLLAWKKGLNPIRLVLVGIGVNAAFSAAILMLQLKMDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEEECCH
NDFMQAAVWLSGNIWSSNWSFVSAVLPWIVVLIPFILYKARYLNVLNLGDQLATGLGTAV
HHHHHHHHHEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EKERRTLLLSAAALSGACVAAGGNITFLGLVAPHIARRLVGPKHQLLIPASALTGALLFL
HHHHHHHEEEHHHHCCEEEEECCCEEEHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
LADLIGRMILAPSEIPVGLVIAALGAPYFIYLLMKTN
HHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure
MLKKNNRRAGAVMLVMAVLTAAVFLLSMNMGEIRIDPLATLRTLFGFGTPQDELVLFEFR
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCCCCCCCEEEEEEH
LPRMILAMLIGAGVAVSGAVWQGISRNDLADPGILGINTGAGFAVVLFIFYFQGDVGNLQ
HHHHHHHHHHHCCHHCCHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCC
KGFVFSLPIFAFLGACFAVVSIYLLAWKKGLNPIRLVLVGIGVNAAFSAAILMLQLKMDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEEECCH
NDFMQAAVWLSGNIWSSNWSFVSAVLPWIVVLIPFILYKARYLNVLNLGDQLATGLGTAV
HHHHHHHHHEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EKERRTLLLSAAALSGACVAAGGNITFLGLVAPHIARRLVGPKHQLLIPASALTGALLFL
HHHHHHHEEEHHHHCCEEEEECCCEEEHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
LADLIGRMILAPSEIPVGLVIAALGAPYFIYLLMKTN
HHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]