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The map label for this gene is mrpC [H]

Identifier: 52787042

GI number: 52787042

Start: 3201659

End: 3202000

Strand: Direct

Name: mrpC [H]

Synonym: BLi03347

Alternate gene names: 52787042

Gene position: 3201659-3202000 (Clockwise)

Preceding gene: 52787041

Following gene: 52787043

Centisome position: 75.82

GC content: 45.91

Gene sequence:

>342_bases
ATGGAGATTTTAATGTCTTTTATTGTAGGAATTCTGTTCATGGCGGCGACTTATCTGCTGCTTTCCAAAAGCCTTTTGAG
GGTGATTATCGGAACTGCCGTTCTCAGCCATGGCGTCCATCTGCTTTTGCTGACGATGGGAGGGTTAAAAAAAGGAGCGC
CCCCCATTTTGAATGAAGAGTCGACAACCTATGTCGATCCTCTCCCTCAGGCGTTGATTTTAACGGCGATCGTCATTGCT
TTCGGGGTTACCTCGTTTCTCCTGGTCATGGCTTTCCGCGCCTATCAAGAGCTGAAAATGGATGATATGGATCAAATGAG
GGGAAATGATCAACATGAATAA

Upstream 100 bases:

>100_bases
AAACGGAGCTTGCCACCGCGGTATTGTTTGATATCGGGGTTTATCTCGTAGTGGTCGGCGTGACCATGACCATTATTCAG
ACGATTGGGGAGAGAGAATA

Downstream 100 bases:

>100_bases
TCTTGTAATTCTGCCAATACTGATTCCTTTAATGGCCGCAATTCTGCTTATCTTTATGAACAGGTCGATCGTGCTGATGC
GTGCATTCAGCGCCATATCT

Product: putative monovalent cation/H+ antiporter subunit C

Products: NA

Alternate protein names: Mrp complex subunit C; Multiple resistance and pH homeostasis protein C [H]

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MEILMSFIVGILFMAATYLLLSKSLLRVIIGTAVLSHGVHLLLLTMGGLKKGAPPILNEESTTYVDPLPQALILTAIVIA
FGVTSFLLVMAFRAYQELKMDDMDQMRGNDQHE

Sequences:

>Translated_113_residues
MEILMSFIVGILFMAATYLLLSKSLLRVIIGTAVLSHGVHLLLLTMGGLKKGAPPILNEESTTYVDPLPQALILTAIVIA
FGVTSFLLVMAFRAYQELKMDDMDQMRGNDQHE
>Mature_113_residues
MEILMSFIVGILFMAATYLLLSKSLLRVIIGTAVLSHGVHLLLLTMGGLKKGAPPILNEESTTYVDPLPQALILTAIVIA
FGVTSFLLVMAFRAYQELKMDDMDQMRGNDQHE

Specific function: Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual N

COG id: COG1006

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhC subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001133 [H]

Pfam domain/function: PF00420 Oxidored_q2 [H]

EC number: NA

Molecular weight: Translated: 12437; Mature: 12437

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILMSFIVGILFMAATYLLLSKSLLRVIIGTAVLSHGVHLLLLTMGGLKKGAPPILNEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STTYVDPLPQALILTAIVIAFGVTSFLLVMAFRAYQELKMDDMDQMRGNDQHE
CCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
>Mature Secondary Structure
MEILMSFIVGILFMAATYLLLSKSLLRVIIGTAVLSHGVHLLLLTMGGLKKGAPPILNEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STTYVDPLPQALILTAIVIAFGVTSFLLVMAFRAYQELKMDDMDQMRGNDQHE
CCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10198001; 11356194 [H]