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The map label for this gene is comEA [H]

Identifier: 52786487

GI number: 52786487

Start: 2648753

End: 2649382

Strand: Reverse

Name: comEA [H]

Synonym: BLi02752

Alternate gene names: 52786487

Gene position: 2649382-2648753 (Counterclockwise)

Preceding gene: 52786489

Following gene: 52786486

Centisome position: 62.74

GC content: 48.57

Gene sequence:

>630_bases
TTGACAGATTGGCTAAAACAATATAAATGGCATGCTGCGGGAGGCGTTGCACTCGTCTTGATCATCAGCGCTGCCTTCAT
GCTGTTAAGCGGAAAGCGTGAAACTTCATCCGGCCTCTCCATTCCCGAGGAGGCTTCTGCACAGACGTATGACAAGAAGG
AGGAGGTGAAACGGGAAAAAAGCGCGGGAAAAGAGGCGGTTATCATCGATTTGAAAGGCGCTGTGAAAAATCCGGGCGTC
TATCAAATGAAAGAGGGAGACAGGGTCCACGATGTATTGAAAAAAGCAGGCGGCACCGAGAAAAAAGCGGATCAAAAGCA
AATTAACCTTGCAGCCGTTTTGCAGGACGGTATGGTGGTTTACATTCCATTTGAGGGGGAAGAGGCTGCTGATTCTTTCT
CGAAAGCGGGTTCAAGGGCAGATGGCGCTTCCGTCGATATCGTCAATATCAATACGGCTTCCTCTGAGGAGCTTCAGGCG
ATTCCCGGCATCGGCCCTTCAAAAGCGGAAGCGGTTATCGAATACCGCGAGGAGAACGGACCGTTTCACACGGTAGAAGA
CATAACAAACGTTTCGGGAATTGGAGAAAAGTCTTTTGAAAGAATAAAATCTGCAATCACGGTAAAGTAA

Upstream 100 bases:

>100_bases
ATAAAGCCGATATTCAATCGTTCTCCCCTCCTTTGAACCTGTATCTTTTAAACGATATGAAGGCTTCAGTCAAAATATGT
ATGAAAGCAGGTGAGCAGGT

Downstream 100 bases:

>100_bases
ATTGACGTTTGCGGATCATCATATGTAAACTTAGGGAAGTCGACATCGTATTTTTGGAGGGAAAACAAGTGGAACGGATT
TCTTGGGATCAATATTTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTDWLKQYKWHAAGGVALVLIISAAFMLLSGKRETSSGLSIPEEASAQTYDKKEEVKREKSAGKEAVIIDLKGAVKNPGV
YQMKEGDRVHDVLKKAGGTEKKADQKQINLAAVLQDGMVVYIPFEGEEAADSFSKAGSRADGASVDIVNINTASSEELQA
IPGIGPSKAEAVIEYREENGPFHTVEDITNVSGIGEKSFERIKSAITVK

Sequences:

>Translated_209_residues
MTDWLKQYKWHAAGGVALVLIISAAFMLLSGKRETSSGLSIPEEASAQTYDKKEEVKREKSAGKEAVIIDLKGAVKNPGV
YQMKEGDRVHDVLKKAGGTEKKADQKQINLAAVLQDGMVVYIPFEGEEAADSFSKAGSRADGASVDIVNINTASSEELQA
IPGIGPSKAEAVIEYREENGPFHTVEDITNVSGIGEKSFERIKSAITVK
>Mature_208_residues
TDWLKQYKWHAAGGVALVLIISAAFMLLSGKRETSSGLSIPEEASAQTYDKKEEVKREKSAGKEAVIIDLKGAVKNPGVY
QMKEGDRVHDVLKKAGGTEKKADQKQINLAAVLQDGMVVYIPFEGEEAADSFSKAGSRADGASVDIVNINTASSEELQAI
PGIGPSKAEAVIEYREENGPFHTVEDITNVSGIGEKSFERIKSAITVK

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

Organism=Escherichia coli, GI1786646, Length=62, Percent_Identity=50, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 22469; Mature: 22337

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDWLKQYKWHAAGGVALVLIISAAFMLLSGKRETSSGLSIPEEASAQTYDKKEEVKREK
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHH
SAGKEAVIIDLKGAVKNPGVYQMKEGDRVHDVLKKAGGTEKKADQKQINLAAVLQDGMVV
HCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHEEECCCEEE
YIPFEGEEAADSFSKAGSRADGASVDIVNINTASSEELQAIPGIGPSKAEAVIEYREENG
EEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHCCC
PFHTVEDITNVSGIGEKSFERIKSAITVK
CEEHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDWLKQYKWHAAGGVALVLIISAAFMLLSGKRETSSGLSIPEEASAQTYDKKEEVKREK
CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHH
SAGKEAVIIDLKGAVKNPGVYQMKEGDRVHDVLKKAGGTEKKADQKQINLAAVLQDGMVV
HCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHEEECCCEEE
YIPFEGEEAADSFSKAGSRADGASVDIVNINTASSEELQAIPGIGPSKAEAVIEYREENG
EEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHCCC
PFHTVEDITNVSGIGEKSFERIKSAITVK
CEEHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]