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The map label for this gene is comEB [H]

Identifier: 52786486

GI number: 52786486

Start: 2648115

End: 2648684

Strand: Reverse

Name: comEB [H]

Synonym: BLi02751

Alternate gene names: 52786486

Gene position: 2648684-2648115 (Counterclockwise)

Preceding gene: 52786487

Following gene: 52786485

Centisome position: 62.73

GC content: 46.49

Gene sequence:

>570_bases
GTGGAACGGATTTCTTGGGATCAATATTTTATGGCGCAAAGCCATTTGCTGGCGCTTCGCAGCACGTGTACAAGGCTTGC
TGTAGGAGCGACGATTGTCAGGGATAAACGAATTATAGCGGGAGGCTACAACGGATCGATCGCCGGAGGCGTTCACTGTG
CGGATGAAGGCTGCTATATGGTGGACGGGCACTGCATTAGAACGATTCACGCCGAGATGAACGCGATTCTTCAGTGTGCA
AAATTCGGTGTTCCGACCGAAGGCGCTGAAATATATGTCACACATTTTCCGTGCATTCAATGCTGTAAATCGATCATTCA
GGCAGGTATTAAAACGATATACTATGCGAAGGATTACAAAAACCATCCTTACGCGGTTGAACTTTTCGATCAGGCTTCTG
TTAAAGTGGAGCAGGTAGAGCTCGATGAGATGATTATCGACTTGAAAAACCAGGAAAAGTTGGCGTTTGTAGCCGATCTG
ATCAAACAGCTGGCTGATAAAGGCCTTGAGGAAGAGGAGATCAGGAAAATACACGAAGAGGCCAACAAACTGTTTACAAG
CTACGTGTAA

Upstream 100 bases:

>100_bases
AAAGAATAAAATCTGCAATCACGGTAAAGTAAATTGACGTTTGCGGATCATCATATGTAAACTTAGGGAAGTCGACATCG
TATTTTTGGAGGGAAAACAA

Downstream 100 bases:

>100_bases
CCAATGGACAGACATCGCATCTTCCCGTGCGGAGCGATTTCAGCGGCAGCCGGAATCGCCTCCGCTCACTCTTCTCTTTA
TCTCTTCCTCGCCGTCGGTT

Product: hypothetical protein

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MERISWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGVHCADEGCYMVDGHCIRTIHAEMNAILQCA
KFGVPTEGAEIYVTHFPCIQCCKSIIQAGIKTIYYAKDYKNHPYAVELFDQASVKVEQVELDEMIIDLKNQEKLAFVADL
IKQLADKGLEEEEIRKIHEEANKLFTSYV

Sequences:

>Translated_189_residues
MERISWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGVHCADEGCYMVDGHCIRTIHAEMNAILQCA
KFGVPTEGAEIYVTHFPCIQCCKSIIQAGIKTIYYAKDYKNHPYAVELFDQASVKVEQVELDEMIIDLKNQEKLAFVADL
IKQLADKGLEEEEIRKIHEEANKLFTSYV
>Mature_189_residues
MERISWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGVHCADEGCYMVDGHCIRTIHAEMNAILQCA
KFGVPTEGAEIYVTHFPCIQCCKSIIQAGIKTIYYAKDYKNHPYAVELFDQASVKVEQVELDEMIIDLKNQEKLAFVADL
IKQLADKGLEEEEIRKIHEEANKLFTSYV

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=123, Percent_Identity=38.2113821138211, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI61742821, Length=123, Percent_Identity=38.2113821138211, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321938, Length=149, Percent_Identity=34.8993288590604, Blast_Score=92, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24667298, Length=136, Percent_Identity=38.9705882352941, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24667302, Length=136, Percent_Identity=38.9705882352941, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 21253; Mature: 21253

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERISWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGVHCADEGCYM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEECCCCCCCCCCEEECCCCCEE
VDGHCIRTIHAEMNAILQCAKFGVPTEGAEIYVTHFPCIQCCKSIIQAGIKTIYYAKDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEECCCC
NHPYAVELFDQASVKVEQVELDEMIIDLKNQEKLAFVADLIKQLADKGLEEEEIRKIHEE
CCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ANKLFTSYV
HHHHHHHCC
>Mature Secondary Structure
MERISWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGVHCADEGCYM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEECCCCCCCCCCEEECCCCCEE
VDGHCIRTIHAEMNAILQCAKFGVPTEGAEIYVTHFPCIQCCKSIIQAGIKTIYYAKDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEECCCC
NHPYAVELFDQASVKVEQVELDEMIIDLKNQEKLAFVADLIKQLADKGLEEEEIRKIHEE
CCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ANKLFTSYV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]