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The map label for this gene is hrcA

Identifier: 52786476

GI number: 52786476

Start: 2636698

End: 2637729

Strand: Reverse

Name: hrcA

Synonym: BLi02741

Alternate gene names: 52786476

Gene position: 2637729-2636698 (Counterclockwise)

Preceding gene: 52786477

Following gene: 52786475

Centisome position: 62.47

GC content: 45.74

Gene sequence:

>1032_bases
ATGTTAACAAATCGTCAGCTGTTAATCTTGCAGGTTATCGTCAACGATTTCATTCGTTCAGCTCAGCCGGTAGGATCAAG
AACGCTTTCCAAAAAGGAAGATATCACATTCAGCTCGGCAACGATCAGAAACGAAATGGCTGACTTGGAAGAGCTCGGTT
TTATCGAAAAAACCCACTCATCTTCAGGCCGGATTCCTTCTGAAAAGGGCTATCGCTATTATGTCGATCATCTGCTTTCA
CCTGGAAAGCTGTCAAAAACGGACTTAAACATTATTCATTCGATTTTCAAAGAAAAAATCTTTGAACTCGAAAAAGCCGT
GCAGAAGTCGGCCCAAGTGCTGTCCGACCTGACAAATTATACATCGATTGTCCTCGGTCCGAGACTGAGTGAAAACCATC
TCAAACAGATCCAGATTGTACCGATTCAGCCCAAGAAGGCCGTTGCCATTCTAGTAACGAATACCGGCCATGTGGAGAAT
AAAACGATTAATTTCCCGGCGGAGGTCGATCTTTCCGATCTCGAGAAGCTGGTGAATATATTAAATGAACGCCTTAGAGG
CGTGCCGATCTCAGAACTGAAAGACAGGATTTTCAAAGAGGTTGTCATCTTCTTGAAGTCGCACATTCAAAATTACGATA
CGATTTTGCACGCGCTCGGCGCAACGCTGGATTCATCTGTTCAAACCGACCGGCTGTTTTTCGGCGGCAAGATTAACATG
CTGAACCAGCCCGAATTTCACGATATTGACAGAGTGAAATCGCTATTGTCGCTCATTGAGAAAGAACAGGAGATTCTCCG
GCTCTTTCAGTCGACTGAGTCCGGAATTACCATCAAAATCGGCAAAGAAAACGACTATGAAGAGATGGAAAACTGCAGCC
TGATTACCGCAACATACACGGTCGGCTCAAAACAGATCGGCTCCATTGCGGTCATCGGACCGACGCGCATGGACTACTCC
CGCGTCGTCGGCTTGCTTCAGCACGTATCATCTGACTTGTCAAAAGCGCTGACAAGTTTGTATGATGGGTAA

Upstream 100 bases:

>100_bases
CATTCCTGGGTGAGTTATAATTGACATTTTGATTTCGGTTTGGTAATTTTGATATACAATTAGCACTCAGTTGTGCCGAG
TGCTAACAGGGGTGATATGG

Downstream 100 bases:

>100_bases
GGCAGTACCTGAAAACAAACAGAAGGGAGGAATCCCTTCTTTATCATGAAACTCATCCTTTAAGGGAGGTGAACACAGAT
GGCAGAAGAAAAACAAAACG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLTNRQLLILQVIVNDFIRSAQPVGSRTLSKKEDITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRYYVDHLLS
PGKLSKTDLNIIHSIFKEKIFELEKAVQKSAQVLSDLTNYTSIVLGPRLSENHLKQIQIVPIQPKKAVAILVTNTGHVEN
KTINFPAEVDLSDLEKLVNILNERLRGVPISELKDRIFKEVVIFLKSHIQNYDTILHALGATLDSSVQTDRLFFGGKINM
LNQPEFHDIDRVKSLLSLIEKEQEILRLFQSTESGITIKIGKENDYEEMENCSLITATYTVGSKQIGSIAVIGPTRMDYS
RVVGLLQHVSSDLSKALTSLYDG

Sequences:

>Translated_343_residues
MLTNRQLLILQVIVNDFIRSAQPVGSRTLSKKEDITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRYYVDHLLS
PGKLSKTDLNIIHSIFKEKIFELEKAVQKSAQVLSDLTNYTSIVLGPRLSENHLKQIQIVPIQPKKAVAILVTNTGHVEN
KTINFPAEVDLSDLEKLVNILNERLRGVPISELKDRIFKEVVIFLKSHIQNYDTILHALGATLDSSVQTDRLFFGGKINM
LNQPEFHDIDRVKSLLSLIEKEQEILRLFQSTESGITIKIGKENDYEEMENCSLITATYTVGSKQIGSIAVIGPTRMDYS
RVVGLLQHVSSDLSKALTSLYDG
>Mature_343_residues
MLTNRQLLILQVIVNDFIRSAQPVGSRTLSKKEDITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRYYVDHLLS
PGKLSKTDLNIIHSIFKEKIFELEKAVQKSAQVLSDLTNYTSIVLGPRLSENHLKQIQIVPIQPKKAVAILVTNTGHVEN
KTINFPAEVDLSDLEKLVNILNERLRGVPISELKDRIFKEVVIFLKSHIQNYDTILHALGATLDSSVQTDRLFFGGKINM
LNQPEFHDIDRVKSLLSLIEKEQEILRLFQSTESGITIKIGKENDYEEMENCSLITATYTVGSKQIGSIAVIGPTRMDYS
RVVGLLQHVSSDLSKALTSLYDG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_BACLD (Q65H52)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079889.1
- RefSeq:   YP_092305.1
- HSSP:   Q9WZV5
- ProteinModelPortal:   Q65H52
- SMR:   Q65H52
- STRING:   Q65H52
- EnsemblBacteria:   EBBACT00000056410
- EnsemblBacteria:   EBBACT00000060991
- GeneID:   3027305
- GeneID:   3097788
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02741
- KEGG:   bli:BL02094
- NMPDR:   fig|279010.5.peg.3012
- eggNOG:   COG1420
- GeneTree:   EBGT00050000002539
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- BioCyc:   BLIC279010-1:BLI02741-MONOMER
- BioCyc:   BLIC279010:BL02094-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38527; Mature: 38527

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNRQLLILQVIVNDFIRSAQPVGSRTLSKKEDITFSSATIRNEMADLEELGFIEKTHS
CCCCCHHHHHHHHHHHHHHCCCCCCCHHCCHHHCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRIPSEKGYRYYVDHLLSPGKLSKTDLNIIHSIFKEKIFELEKAVQKSAQVLSDLTNY
CCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIVLGPRLSENHLKQIQIVPIQPKKAVAILVTNTGHVENKTINFPAEVDLSDLEKLVNI
HHEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHH
LNERLRGVPISELKDRIFKEVVIFLKSHIQNYDTILHALGATLDSSVQTDRLFFGGKINM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEECC
LNQPEFHDIDRVKSLLSLIEKEQEILRLFQSTESGITIKIGKENDYEEMENCSLITATYT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCEEEEEEEE
VGSKQIGSIAVIGPTRMDYSRVVGLLQHVSSDLSKALTSLYDG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTNRQLLILQVIVNDFIRSAQPVGSRTLSKKEDITFSSATIRNEMADLEELGFIEKTHS
CCCCCHHHHHHHHHHHHHHCCCCCCCHHCCHHHCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRIPSEKGYRYYVDHLLSPGKLSKTDLNIIHSIFKEKIFELEKAVQKSAQVLSDLTNY
CCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIVLGPRLSENHLKQIQIVPIQPKKAVAILVTNTGHVENKTINFPAEVDLSDLEKLVNI
HHEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHH
LNERLRGVPISELKDRIFKEVVIFLKSHIQNYDTILHALGATLDSSVQTDRLFFGGKINM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEECC
LNQPEFHDIDRVKSLLSLIEKEQEILRLFQSTESGITIKIGKENDYEEMENCSLITATYT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCEEEEEEEE
VGSKQIGSIAVIGPTRMDYSRVVGLLQHVSSDLSKALTSLYDG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA