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The map label for this gene is yodS [H]

Identifier: 52786042

GI number: 52786042

Start: 2251914

End: 2252606

Strand: Reverse

Name: yodS [H]

Synonym: BLi02298

Alternate gene names: 52786042

Gene position: 2252606-2251914 (Counterclockwise)

Preceding gene: 52786043

Following gene: 52786041

Centisome position: 53.35

GC content: 49.78

Gene sequence:

>693_bases
ATGACGATGCCGAACAAACGTATTGCTGTTGAAGATGCCATTGCCGATTTGAAAGACGAAGCGACCGTCATGTTTGGCGG
ATTTGGGGGAGTCGGTTCACCGCCTTCTTTCATCCGGGCGATTTTGAAAAAAGGCGTAAAAAATTTAACGGTCATATGCA
ATGATGCAGGATTTCCCGGCATCGGGATCGGCCCATTAATCGTCAATAACCGCGTAAGGCGGCTGATCGCTTCTCATATC
GGTTCAAATCCCGTTGCGGGAAAACAAATGACCGACGGTTTTCTCGCCGTTGAATTTTCTCCGCAAGGTACGCTGGCCGA
ACGAATTCGTGCGGGCGGCACAGGTCTTGGCGGCATTTTGACCGATATCGGGATCGATAATGACATGGTGCGCCAAGGAA
AGAATATCGTTTCATTAAACGGACGCGCATACCTTGCCGAGGAAGCCTTGAGTGCGGAATACGCTTTCATTTATGGAAAA
ACCGCCGATGAATTCGGCAATATCATCTACGACAAAACGGCTCGCAACATGAACCCGCTTATGGCGATGGCTGCTGATCG
GACATTTGCCGAGGTCGAGCGGATCGTTCCCATTGGAGAGCTCGATGAAGAAGAAATTGTAACACCCGGTGTTTTTGTCG
AAGGTGTAGCTGAAACGGAAGGGGTGAACTGGAAATGGGTTTGGGAGTCATAG

Upstream 100 bases:

>100_bases
CTCTTACGATATCGGACAAAGAAATGGAAGAGCTCATTGAAATATTTAAACATGCCGTATATGAGATTGAAAAACAAGCG
GAAAAGGTGATGCGCGAAAG

Downstream 100 bases:

>100_bases
AGCGGGAGAGAATCGCGAAACGGGCGGCCCGCGAAATCAAAAGCGGAATGATTGTCAATCTGGGCATTGGCATTCCGTCT
TTAGTTCCCAACTTTTTAGA

Product: YodS

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: Probable CoA-transferase subunit alpha [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTMPNKRIAVEDAIADLKDEATVMFGGFGGVGSPPSFIRAILKKGVKNLTVICNDAGFPGIGIGPLIVNNRVRRLIASHI
GSNPVAGKQMTDGFLAVEFSPQGTLAERIRAGGTGLGGILTDIGIDNDMVRQGKNIVSLNGRAYLAEEALSAEYAFIYGK
TADEFGNIIYDKTARNMNPLMAMAADRTFAEVERIVPIGELDEEEIVTPGVFVEGVAETEGVNWKWVWES

Sequences:

>Translated_230_residues
MTMPNKRIAVEDAIADLKDEATVMFGGFGGVGSPPSFIRAILKKGVKNLTVICNDAGFPGIGIGPLIVNNRVRRLIASHI
GSNPVAGKQMTDGFLAVEFSPQGTLAERIRAGGTGLGGILTDIGIDNDMVRQGKNIVSLNGRAYLAEEALSAEYAFIYGK
TADEFGNIIYDKTARNMNPLMAMAADRTFAEVERIVPIGELDEEEIVTPGVFVEGVAETEGVNWKWVWES
>Mature_229_residues
TMPNKRIAVEDAIADLKDEATVMFGGFGGVGSPPSFIRAILKKGVKNLTVICNDAGFPGIGIGPLIVNNRVRRLIASHIG
SNPVAGKQMTDGFLAVEFSPQGTLAERIRAGGTGLGGILTDIGIDNDMVRQGKNIVSLNGRAYLAEEALSAEYAFIYGKT
ADEFGNIIYDKTARNMNPLMAMAADRTFAEVERIVPIGELDEEEIVTPGVFVEGVAETEGVNWKWVWES

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=227, Percent_Identity=37.8854625550661, Blast_Score=154, Evalue=4e-38,
Organism=Homo sapiens, GI11545841, Length=222, Percent_Identity=36.9369369369369, Blast_Score=137, Evalue=8e-33,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=46.2616822429907, Blast_Score=201, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17531517, Length=225, Percent_Identity=33.7777777777778, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21358325, Length=231, Percent_Identity=40.2597402597403, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24655794, Length=231, Percent_Identity=40.2597402597403, Blast_Score=168, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 24678; Mature: 24546

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMPNKRIAVEDAIADLKDEATVMFGGFGGVGSPPSFIRAILKKGVKNLTVICNDAGFPG
CCCCCCCEEHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
IGIGPLIVNNRVRRLIASHIGSNPVAGKQMTDGFLAVEFSPQGTLAERIRAGGTGLGGIL
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHH
TDIGIDNDMVRQGKNIVSLNGRAYLAEEALSAEYAFIYGKTADEFGNIIYDKTARNMNPL
HHCCCCHHHHHCCCCEEEECCCEEEHHHHHCCCEEEEECCCHHHHCCEEECCCCCCCCHH
MAMAADRTFAEVERIVPIGELDEEEIVTPGVFVEGVAETEGVNWKWVWES
HHHHHCCHHHHHHHHCCCCCCCHHHCCCCCCEEECCHHCCCCCEEEEECC
>Mature Secondary Structure 
TMPNKRIAVEDAIADLKDEATVMFGGFGGVGSPPSFIRAILKKGVKNLTVICNDAGFPG
CCCCCCEEHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
IGIGPLIVNNRVRRLIASHIGSNPVAGKQMTDGFLAVEFSPQGTLAERIRAGGTGLGGIL
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHH
TDIGIDNDMVRQGKNIVSLNGRAYLAEEALSAEYAFIYGKTADEFGNIIYDKTARNMNPL
HHCCCCHHHHHCCCCEEEECCCEEEHHHHHCCCEEEEECCCHHHHCCEEECCCCCCCCHH
MAMAADRTFAEVERIVPIGELDEEEIVTPGVFVEGVAETEGVNWKWVWES
HHHHHCCHHHHHHHHCCCCCCCHHHCCCCCCEEECCHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]