Click here to switch to the map view.

The map label for this gene is tetB [H]

Identifier: 52785699

GI number: 52785699

Start: 1903533

End: 1904096

Strand: Direct

Name: tetB [H]

Synonym: BLi01941

Alternate gene names: 52785699

Gene position: 1903533-1904096 (Clockwise)

Preceding gene: 52785698

Following gene: 52785700

Centisome position: 45.08

GC content: 48.58

Gene sequence:

>564_bases
TTGAAAAACAGTAAAATACAAACCTTTAAACATCAAAAGAAGGCATTTTGGTGGCTTAGCTTTGTCGCTTTCTTCAGCGT
GATGAACGAAACCGTATTTAATGTTGCATTGCCGGACATAAAAAATCAATTCGGCGTGTCGCCTGCGGCGGCAAATTGGG
TGAATACGAGTTTCATCATTTCCTTTGCTGCCGGTTCAGTTGTTTACAGCAGGCTTTCTGATATGTACGGCGTCAGGAAG
CTGTTTGTGGCCGGACTGCTCATCTATGGCGGAGGCTCATTTATGGGTTTGTTGGCTCAAGCTTATTTCCCGGCTGTGAT
CTTTGCGCGCTTTGTTCAAGGATCCGGGGCTTCCGCTGTACCCGCGCTTATCCTGGTCATCATCACGCGCTATGTCCGTC
CGGAGGGCCGGGGCAAAGCATTCGGCATTGTCGGATCACTGGTGGCAATGGGCGAGGGAATAGGTCCGGCCATCGGCGGA
ATGATTGATTGTACATTATATTCATTGGTCGTTTCTGTTTATTCTGCCGATGGCAGTGCTGATGGCGATTCCTTTCTTCT
TTAG

Upstream 100 bases:

>100_bases
TGAAGTGCAAAAAAATAAGTGGGTTAACATTCGAGGGGAAAGCGCATCATTAACCCTATAAACTGCGTGATTCCCCTTTA
ATTTTGGGGGTATCATTCAA

Downstream 100 bases:

>100_bases
AAATATGCCTGATGAAGCCGCTGCAAAAGCAAACCTGGATATCATTGGGATCGGACTGCTGACAATCAGCATTGTGATGT
TCGCTGTATATATATCGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKNSKIQTFKHQKKAFWWLSFVAFFSVMNETVFNVALPDIKNQFGVSPAAANWVNTSFIISFAAGSVVYSRLSDMYGVRK
LFVAGLLIYGGGSFMGLLAQAYFPAVIFARFVQGSGASAVPALILVIITRYVRPEGRGKAFGIVGSLVAMGEGIGPAIGG
MIDCTLYSLVVSVYSADGSADGDSFLL

Sequences:

>Translated_187_residues
MKNSKIQTFKHQKKAFWWLSFVAFFSVMNETVFNVALPDIKNQFGVSPAAANWVNTSFIISFAAGSVVYSRLSDMYGVRK
LFVAGLLIYGGGSFMGLLAQAYFPAVIFARFVQGSGASAVPALILVIITRYVRPEGRGKAFGIVGSLVAMGEGIGPAIGG
MIDCTLYSLVVSVYSADGSADGDSFLL
>Mature_187_residues
MKNSKIQTFKHQKKAFWWLSFVAFFSVMNETVFNVALPDIKNQFGVSPAAANWVNTSFIISFAAGSVVYSRLSDMYGVRK
LFVAGLLIYGGGSFMGLLAQAYFPAVIFARFVQGSGASAVPALILVIITRYVRPEGRGKAFGIVGSLVAMGEGIGPAIGG
MIDCTLYSLVVSVYSADGSADGDSFLL

Specific function: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 19965; Mature: 19965

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSKIQTFKHQKKAFWWLSFVAFFSVMNETVFNVALPDIKNQFGVSPAAANWVNTSFII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHH
SFAAGSVVYSRLSDMYGVRKLFVAGLLIYGGGSFMGLLAQAYFPAVIFARFVQGSGASAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
PALILVIITRYVRPEGRGKAFGIVGSLVAMGEGIGPAIGGMIDCTLYSLVVSVYSADGSA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DGDSFLL
CCCCCCC
>Mature Secondary Structure
MKNSKIQTFKHQKKAFWWLSFVAFFSVMNETVFNVALPDIKNQFGVSPAAANWVNTSFII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHH
SFAAGSVVYSRLSDMYGVRKLFVAGLLIYGGGSFMGLLAQAYFPAVIFARFVQGSGASAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
PALILVIITRYVRPEGRGKAFGIVGSLVAMGEGIGPAIGGMIDCTLYSLVVSVYSADGSA
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DGDSFLL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2844262; 7584024; 9384377 [H]