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The map label for this gene is asd [H]

Identifier: 52785659

GI number: 52785659

Start: 1858853

End: 1859893

Strand: Direct

Name: asd [H]

Synonym: BLi01900

Alternate gene names: 52785659

Gene position: 1858853-1859893 (Clockwise)

Preceding gene: 52785658

Following gene: 52785660

Centisome position: 44.02

GC content: 46.88

Gene sequence:

>1041_bases
TTGGGCAGAGGATTACATGTAGCAGTAGTTGGTGCGACAGGCGCTGTAGGACAGCAAATGTTAAAAACACTAGAAGACAG
GAATTTTGAACTGGATAAACTGACTTTATTATCCTCAAAACGTTCAGCAGGTACGAAACTGACTTTCAAAGGCGAAGAGT
ACACAGTAGAAGAAGCTCGTCCTGAGAGCTTTGAAGGCGTCAACATCGCGCTTTTCAGCGCCGGGGGAAGCGTTTCGCAG
GCGCTTGCTCACGAGGCTGTCAAACGCGGGGCGATCGTCATTGATAATACGAGCGCGTTCCGGATGGACCAAAACACTCC
GCTCGTCGTACCTGAGGTCAATGAGGAAGATTTGCACAAGCACAACGGGATTATTGCAAATCCGAACTGTTCAACCATCC
AGATGGTTGTTGCGCTCGAACCGATCCGCAAGGCTTTCGGTTTAAACAAAATCATCGTATCGACTTATCAGGCGGTGTCT
GGAGCCGGAAACGAAGCTGTAAAAGAGCTCTACGGGCAAACCGAAGCCATTTTGAACGACAAACCGTTCGAGCCTGAGAT
CATGCCGGTGAAGAGTGATGAAAAACACTACCAAATCGCATTTAACGCTATTCCTCAAATCGATAAATTCCAGGAAAACG
GCTTTACGTTTGAGGAAATGAAAATGATAAATGAAACGAAAAAAATCATGCACATGCCTGAGCTTCAAGTTTCAGCCACA
TGTGTCAGACTGCCGATTGCAACAGGGCATTCAGAATCCGTCTACATCGAAACAGACCGTGATGATGTGACAGCAGAGGA
TATTAAAAATCTGTTAAAAGAAGCTCCAGGCGTCGTTCTGCAGGATGATCCAGCTAAACAGGTCTATCCGATGCCTGCAG
ATGCAGTAGGGAAAAGAGACGTATTTGTCGGCCGGGTGAGAAAAGACCTTGACCGCCCGAACGGTTTCCATCTGTGGATC
GTTTCCGACAACCTGCTGAAAGGCGCGGCATGGAATTCCGTACAAATCGCAGAAAGCCTAAAAGCTTTAAATTTAGTTTA
A

Upstream 100 bases:

>100_bases
AAAATATCAATCACCACGGCACACATCTATGTTAAAATAAAATGTAAAATGCATAGTCAACCAATCGTTTACGACGATTA
AGGTGGAAGGAGTTTTACAA

Downstream 100 bases:

>100_bases
GATTTCTAACGGGATGTGAGAAGAGAGTGAGGCAAAAATGAAGGCCTGCTCTCTTCTGTTACGTCCGAAATCAACTTGGA
GTGAAATAAAGTGAAAATCA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MGRGLHVAVVGATGAVGQQMLKTLEDRNFELDKLTLLSSKRSAGTKLTFKGEEYTVEEARPESFEGVNIALFSAGGSVSQ
ALAHEAVKRGAIVIDNTSAFRMDQNTPLVVPEVNEEDLHKHNGIIANPNCSTIQMVVALEPIRKAFGLNKIIVSTYQAVS
GAGNEAVKELYGQTEAILNDKPFEPEIMPVKSDEKHYQIAFNAIPQIDKFQENGFTFEEMKMINETKKIMHMPELQVSAT
CVRLPIATGHSESVYIETDRDDVTAEDIKNLLKEAPGVVLQDDPAKQVYPMPADAVGKRDVFVGRVRKDLDRPNGFHLWI
VSDNLLKGAAWNSVQIAESLKALNLV

Sequences:

>Translated_346_residues
MGRGLHVAVVGATGAVGQQMLKTLEDRNFELDKLTLLSSKRSAGTKLTFKGEEYTVEEARPESFEGVNIALFSAGGSVSQ
ALAHEAVKRGAIVIDNTSAFRMDQNTPLVVPEVNEEDLHKHNGIIANPNCSTIQMVVALEPIRKAFGLNKIIVSTYQAVS
GAGNEAVKELYGQTEAILNDKPFEPEIMPVKSDEKHYQIAFNAIPQIDKFQENGFTFEEMKMINETKKIMHMPELQVSAT
CVRLPIATGHSESVYIETDRDDVTAEDIKNLLKEAPGVVLQDDPAKQVYPMPADAVGKRDVFVGRVRKDLDRPNGFHLWI
VSDNLLKGAAWNSVQIAESLKALNLV
>Mature_345_residues
GRGLHVAVVGATGAVGQQMLKTLEDRNFELDKLTLLSSKRSAGTKLTFKGEEYTVEEARPESFEGVNIALFSAGGSVSQA
LAHEAVKRGAIVIDNTSAFRMDQNTPLVVPEVNEEDLHKHNGIIANPNCSTIQMVVALEPIRKAFGLNKIIVSTYQAVSG
AGNEAVKELYGQTEAILNDKPFEPEIMPVKSDEKHYQIAFNAIPQIDKFQENGFTFEEMKMINETKKIMHMPELQVSATC
VRLPIATGHSESVYIETDRDDVTAEDIKNLLKEAPGVVLQDDPAKQVYPMPADAVGKRDVFVGRVRKDLDRPNGFHLWIV
SDNLLKGAAWNSVQIAESLKALNLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=342, Percent_Identity=33.9181286549708, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789841, Length=367, Percent_Identity=26.158038147139, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320362, Length=398, Percent_Identity=29.6482412060301, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38042; Mature: 37911

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRGLHVAVVGATGAVGQQMLKTLEDRNFELDKLTLLSSKRSAGTKLTFKGEEYTVEEAR
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCEEEECCCEEECCCCC
PESFEGVNIALFSAGGSVSQALAHEAVKRGAIVIDNTSAFRMDQNTPLVVPEVNEEDLHK
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEECCCEEEECCCCCEEEECCCHHHHHH
HNGIIANPNCSTIQMVVALEPIRKAFGLNKIIVSTYQAVSGAGNEAVKELYGQTEAILND
CCCEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCC
KPFEPEIMPVKSDEKHYQIAFNAIPQIDKFQENGFTFEEMKMINETKKIMHMPELQVSAT
CCCCCCEEECCCCCCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEE
CVRLPIATGHSESVYIETDRDDVTAEDIKNLLKEAPGVVLQDDPAKQVYPMPADAVGKRD
EEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHCCCCH
VFVGRVRKDLDRPNGFHLWIVSDNLLKGAAWNSVQIAESLKALNLV
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
GRGLHVAVVGATGAVGQQMLKTLEDRNFELDKLTLLSSKRSAGTKLTFKGEEYTVEEAR
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCEEEECCCEEECCCCC
PESFEGVNIALFSAGGSVSQALAHEAVKRGAIVIDNTSAFRMDQNTPLVVPEVNEEDLHK
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEECCCEEEECCCCCEEEECCCHHHHHH
HNGIIANPNCSTIQMVVALEPIRKAFGLNKIIVSTYQAVSGAGNEAVKELYGQTEAILND
CCCEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCC
KPFEPEIMPVKSDEKHYQIAFNAIPQIDKFQENGFTFEEMKMINETKKIMHMPELQVSAT
CCCCCCEEECCCCCCEEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEE
CVRLPIATGHSESVYIETDRDDVTAEDIKNLLKEAPGVVLQDDPAKQVYPMPADAVGKRD
EEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHCCCCH
VFVGRVRKDLDRPNGFHLWIVSDNLLKGAAWNSVQIAESLKALNLV
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]