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The map label for this gene is polC [H]

Identifier: 52785638

GI number: 52785638

Start: 1832492

End: 1836808

Strand: Direct

Name: polC [H]

Synonym: BLi01879

Alternate gene names: 52785638

Gene position: 1832492-1836808 (Clockwise)

Preceding gene: 52785637

Following gene: 52785639

Centisome position: 43.4

GC content: 48.58

Gene sequence:

>4317_bases
TTGGAAGACCAGCTTTCTGTCAACAGAAGACAGTTTCAAATTCTTCTGCAGCAGCTGAATGTAACGGAAGATACGATGAT
CCGCCACCTTGAAGGCGGACAAATCATAAAGCTGACCGTTCATAAAAACAAGAAGACATGGCACTTTCACTTTAAATTGA
GAAATGTGCTGCCTTATCAAATCTTCGAACGGTTTCACAGCCAGCTGACCCGCACCTTTTCCCATATCGCCCAGGTCACC
TGTTCCATCGAGGCGGAAAACCCTTCGATTGACGAGCAGCTTGTTCAGGATTACTGGACGCGCTGCATTCAGGAACTCGA
TGGTATTTCTCCGCCGATCTTGGCGCTTTTGAACGACCAAAAGCCCAAGCTTACGGGAAACAAAATCCTGCTTAAAACGA
AAACAGATACAGAAGCGTCCGCTTTAAAAAAGAAATACAGCTCGCTCATCCAGTCAAGCTACCGCACATTCGGCTTTCCT
GAGCTCCAGCTGGACACAGAAATTTTTGTATCAGATCAAGAGATTCAGAAATTCAGAGAGCAAAAAATGGCCGAAGATCA
AGAGAGGGCCCTTCAGGCTTTAATCGAAATGGAGAAGCAGGATAAGGAAGCACAAGACGATGAAGCGCCGGCAGGCCCTC
TTCAGATCGGCTACCAGATTAAAGACTCTGAAGAAATCAGAACGCTTGACAGCATCATGGATGAAGAGCGGAGAATTACG
GTGCAAGGCTATGTATTCGACGCTGAAACAAGAGAGCTGAAAAGCGGCAGAACGCTTTGCATCTTTAAAATAACCGACTA
TACAAACAGCATTCTTGTCAAAATGTTCGCCCGCGAAAAAGAAGACGCTGTATTGATGAAGTCCCTGAAAAAAGGGATGT
GGGTCAAGGCGAGAGGAAGCATACAAAACGATACATTCGTCCGCGATTTGGTGATGATCGCCAACGATGTCAATGAAATC
AAAGCGAAAACCCGTGAGGATACAGCGCCAGAGGACGAAAAACGAGTCGAGCTCCACCTCCATTCACCAATGAGCCAGAT
GGATGCCGTATCAAGCATCGGCAAGCTTGTCGAACAGGCGAAAAAATGGGGGCACCCGGCTATCGCGCTCACTGACCATG
CCGTAGTCCAATCGTTTCCGGATGCATTCGCGGCAAGCAAAAAGCATGGCGTGAAAATGATCTACGGACTTGAAGCCAAC
CTCGTCGACGACGGCGTGCCGATTGCCTACAATCCCGTGCACCGTCTGCTTGAAGAGGAAACATATGTCGTGTTCGACGT
CGAGACGACGGGGCTGTCTGCCGTCTATGATACAATCATCGAGCTGGCCGCCGTTAAAGTAAAAGGCGGGGAAATCATCG
AACGCTTTGAAAGGTTTGCCAACCCGCATCGACCTTTATCGGCTACGATCATCGAGCTGACGGGGATTACCGATGATATG
CTGAAAGATGCGCCCGAAGTCGAAGAGGTCATCCGCGATTTTAAAGAATGGGTCGGTGATCACACGCTTGTCGCTCACAA
TGCAAGCTTTGACATCGGCTTCATCAATGTCGCCTATAAGCGCCTGCTGAATTCGGAGAAAGTGCAGAACCCGGTCATTG
ACACGCTTGAGCTGGGCCGTTTTCTTTATCCGGAATTCAAAAACCACAGGCTGAATACGCTTTGTAAAAAGTTTGACATC
GAGCTCACCCAGCATCACAGGGCGATTTATGATACCGAAGCGACGGGTTATCTCCTTGTGAAAATGCTGAAAGATGCGGC
CGAAAAAAATATCCTGTACCACGATCAGCTGAATGAAAATATGGGGCAGTCCAATGCCTATCAGCGTTCAAGGCCATATC
ACGCGACACTTTTGGCGGTTAATGAGACAGGCTTGAAAAACCTTTTCAAACTTGTTTCGCTGTCGCATATCCATTATTTT
TACAGGGTGCCGAGGATCCCAAGGTCACAGCTTGAAAAGTACAGAGAAGGGCTTTTAATCGGTTCGGCGTGCGACAAAGG
CGAAGTATTTGAAGGCATGATGCAGAAATCGCCGGAAGAAGTTGAAGACATCGCTTCATTTTATGACTACCTTGAAGTCA
TGCCGCCTGAAGTCTACCGGCACCTGCTTCAGCTCGAACTCGTCAGGGATGAAAAAGCGTTAAAAGAAATCATCGCCAAC
ATCACAAAGCTCGGCGAGAAGCTGAATATCCCAGTAGTAGCAACTGGAAATGTCCATTATCTGAACCCTGAGGACAAAAT
TTACCGGAAGATTCTAGTTTCCTCGCAAGGCGGCGCAAATCCGCTCAACAGGCACGAGCTGCCGAACGTTCATTTCCGTT
CGACGGATGAAATGCTTGAGGCCTTTTCATTTTTGGGTGAGGAAAAAGCGAAAGAAATCGTTGTCAAGAACACCCGCATG
ATCAGCGAGCGAATCGAAGAAATCAAGCCGATCAAAGACGATCTTTACACACCGAAGATCGAAGGCGCAGATGACGAAAT
CCGCCGCATGAGCTATGAGAAAGCAAGAAGCATTTACGGCGAGGACCTGCCCGAAATCGTCGAAAAACGGATCGAAAAAG
AGCTGAAAAGCATAATCGGCCACGGATTCGCCGTCATCTATCTGATCTCTCATAAGCTTGTAAAACGCTCCCTTGATGAC
GGCTATCTCGTCGGTTCGAGGGGATCGGTCGGTTCTTCCCTTGTCGCAACATTGACGGAAATTACCGAGGTCAACCCGCT
GCCACCGCATTACGTCTGTCCGGATTGCCGCCATTCCGAGTTTTTCAACGACGGATCGGTCGGTTCGGGATTTGATTTGC
CTGACAAAGACTGTCCGAAGTGCGGAGCGGCCTACAGAAAAGACGGCCACGACATTCCGTTTGAGACGTTCCTGGGGTTT
AAAGGGGACAAGGTTCCTGATATCGACTTGAACTTCTCGGGCGAATACCAGCCGCATGCCCACAACTATACGAAAGTCCT
GTTCGGAGAGGATAACGTCTACCGTGCGGGAACGATCGGAACAGTCGCCGAAAAAACGGCTTACGGGTATGTCAAAGGGT
ATGCAAACGACAACAATTTGCATATGCGCGGGGCGGAAATCGACCGACTTGTCCAAGGCTGTACAGGCGTCAAGCGGACG
ACAGGGCAGCACCCGGGCGGAATTATCGTTGTGCCGGATTATATGGATATTTACGACTTTTCACCAATCCAGTTTCCGGC
GGATGCCACAGATTCCGAATGGAAGACGACGCATTTTGACTTCCATTCCATCCATGACAACCTTCTGAAGCTTGATATTC
TCGGACACGATGATCCGACGGTCATCCGTATGCTCCAGGATCTTAGCGGGATTGATCCGAAAACGATTCCGACCGATGAT
CCTGAAGTGATGAAAATTTTCCAAGGGACAGAGTCTTTAGGGGTAACCGAGGAACAGATCGGCTGTAAAACCGGTACACT
CGGCATCCCTGAATTCGGAACCCGCTTTGTCAGACAGATGCTTGAGGACACCAAGCCGACGACATTTTCCGAGCTCGTAC
AGATTTCCGGCCTGTCACACGGTACGGACGTATGGCTCGGCAACGCGCAGGAGCTGATTCACAACAATATTTGTGAACTG
AGCGAAGTGATCGGCTGCCGTGATGACATTATGGTGTACTTAATCTACCAGGGGCTTGAGCCATCCCTCGCCTTTAAGAT
TATGGAGTTTGTCCGTAAAGGAAAGGGACTGACGCCTGAGTGGGAAGAAGAAATGAAGAATAATAATGTTCCGGACTGGT
ATATCGATTCCTGCAAAAAAATCAAATACATGTTCCCGAAAGCCCACGCTGCGGCATATGTTTTGATGGCGGTCAGGATC
GCTTATTTTAAAGTCCATCATCCGCTGCTCTACTACGCAGCATACTTCACCGTGCGGGCCGACGACTTTGACATCGAAAC
GATGATCAAAGGATCGACAGCGATCAGAGCCGTCATGGATGATATCAACTCTAAAGGCCTTGACGCTTCTCCAAAAGAGA
AAAGTTTGCTCACGGTGCTTGAGCTGGCGCTTGAAATGTGCGAAAGGGGCTTCTCTTTCCAAAAAGTCGATTTATACAGA
TCGAGCGCTTCAGAATTCATCATTGATGGAAACAGCTTGATTCCGCCGTTTAATTCAATACCGGGGCTTGGAACAAACGC
CGCCTTGAATATTGTCAAAGCGAGGGAAGAAGGCGAATTTCTTTCCAAAGAAGATTTGCAAAAAAGAGGAAAGGTGTCAA
AAACGATCATGGAATACTTGGAGCGCCACGGCTGTCTCGAGTCGCTTCCAGATCAGAACCAGCTGTCATTATTCTAG

Upstream 100 bases:

>100_bases
TCTCACTCTTAAAACATGGTAAACTAGAGTAAAGGAAGGTACCTCGGGAATCGTCCCAAGGTACCTTCAATTATGATTTT
CTTTTAGGGAGGAATCTGTC

Downstream 100 bases:

>100_bases
AAACTGCCTGCTTAAAGCAGGCAGTTTTTTTATCTGTTTTACGGCATAAAGAGCGTTTTTTCGGAATTGGGTGACAAATG
CCAGGGGAGAAATGATCACA

Product: DNA polymerase III PolC

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 1438; Mature: 1438

Protein sequence:

>1438_residues
MEDQLSVNRRQFQILLQQLNVTEDTMIRHLEGGQIIKLTVHKNKKTWHFHFKLRNVLPYQIFERFHSQLTRTFSHIAQVT
CSIEAENPSIDEQLVQDYWTRCIQELDGISPPILALLNDQKPKLTGNKILLKTKTDTEASALKKKYSSLIQSSYRTFGFP
ELQLDTEIFVSDQEIQKFREQKMAEDQERALQALIEMEKQDKEAQDDEAPAGPLQIGYQIKDSEEIRTLDSIMDEERRIT
VQGYVFDAETRELKSGRTLCIFKITDYTNSILVKMFAREKEDAVLMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEI
KAKTREDTAPEDEKRVELHLHSPMSQMDAVSSIGKLVEQAKKWGHPAIALTDHAVVQSFPDAFAASKKHGVKMIYGLEAN
LVDDGVPIAYNPVHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIERFERFANPHRPLSATIIELTGITDDM
LKDAPEVEEVIRDFKEWVGDHTLVAHNASFDIGFINVAYKRLLNSEKVQNPVIDTLELGRFLYPEFKNHRLNTLCKKFDI
ELTQHHRAIYDTEATGYLLVKMLKDAAEKNILYHDQLNENMGQSNAYQRSRPYHATLLAVNETGLKNLFKLVSLSHIHYF
YRVPRIPRSQLEKYREGLLIGSACDKGEVFEGMMQKSPEEVEDIASFYDYLEVMPPEVYRHLLQLELVRDEKALKEIIAN
ITKLGEKLNIPVVATGNVHYLNPEDKIYRKILVSSQGGANPLNRHELPNVHFRSTDEMLEAFSFLGEEKAKEIVVKNTRM
ISERIEEIKPIKDDLYTPKIEGADDEIRRMSYEKARSIYGEDLPEIVEKRIEKELKSIIGHGFAVIYLISHKLVKRSLDD
GYLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPDCRHSEFFNDGSVGSGFDLPDKDCPKCGAAYRKDGHDIPFETFLGF
KGDKVPDIDLNFSGEYQPHAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYANDNNLHMRGAEIDRLVQGCTGVKRT
TGQHPGGIIVVPDYMDIYDFSPIQFPADATDSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDD
PEVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICEL
SEVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRI
AYFKVHHPLLYYAAYFTVRADDFDIETMIKGSTAIRAVMDDINSKGLDASPKEKSLLTVLELALEMCERGFSFQKVDLYR
SSASEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTIMEYLERHGCLESLPDQNQLSLF

Sequences:

>Translated_1438_residues
MEDQLSVNRRQFQILLQQLNVTEDTMIRHLEGGQIIKLTVHKNKKTWHFHFKLRNVLPYQIFERFHSQLTRTFSHIAQVT
CSIEAENPSIDEQLVQDYWTRCIQELDGISPPILALLNDQKPKLTGNKILLKTKTDTEASALKKKYSSLIQSSYRTFGFP
ELQLDTEIFVSDQEIQKFREQKMAEDQERALQALIEMEKQDKEAQDDEAPAGPLQIGYQIKDSEEIRTLDSIMDEERRIT
VQGYVFDAETRELKSGRTLCIFKITDYTNSILVKMFAREKEDAVLMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEI
KAKTREDTAPEDEKRVELHLHSPMSQMDAVSSIGKLVEQAKKWGHPAIALTDHAVVQSFPDAFAASKKHGVKMIYGLEAN
LVDDGVPIAYNPVHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIERFERFANPHRPLSATIIELTGITDDM
LKDAPEVEEVIRDFKEWVGDHTLVAHNASFDIGFINVAYKRLLNSEKVQNPVIDTLELGRFLYPEFKNHRLNTLCKKFDI
ELTQHHRAIYDTEATGYLLVKMLKDAAEKNILYHDQLNENMGQSNAYQRSRPYHATLLAVNETGLKNLFKLVSLSHIHYF
YRVPRIPRSQLEKYREGLLIGSACDKGEVFEGMMQKSPEEVEDIASFYDYLEVMPPEVYRHLLQLELVRDEKALKEIIAN
ITKLGEKLNIPVVATGNVHYLNPEDKIYRKILVSSQGGANPLNRHELPNVHFRSTDEMLEAFSFLGEEKAKEIVVKNTRM
ISERIEEIKPIKDDLYTPKIEGADDEIRRMSYEKARSIYGEDLPEIVEKRIEKELKSIIGHGFAVIYLISHKLVKRSLDD
GYLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPDCRHSEFFNDGSVGSGFDLPDKDCPKCGAAYRKDGHDIPFETFLGF
KGDKVPDIDLNFSGEYQPHAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYANDNNLHMRGAEIDRLVQGCTGVKRT
TGQHPGGIIVVPDYMDIYDFSPIQFPADATDSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDD
PEVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICEL
SEVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRI
AYFKVHHPLLYYAAYFTVRADDFDIETMIKGSTAIRAVMDDINSKGLDASPKEKSLLTVLELALEMCERGFSFQKVDLYR
SSASEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTIMEYLERHGCLESLPDQNQLSLF
>Mature_1438_residues
MEDQLSVNRRQFQILLQQLNVTEDTMIRHLEGGQIIKLTVHKNKKTWHFHFKLRNVLPYQIFERFHSQLTRTFSHIAQVT
CSIEAENPSIDEQLVQDYWTRCIQELDGISPPILALLNDQKPKLTGNKILLKTKTDTEASALKKKYSSLIQSSYRTFGFP
ELQLDTEIFVSDQEIQKFREQKMAEDQERALQALIEMEKQDKEAQDDEAPAGPLQIGYQIKDSEEIRTLDSIMDEERRIT
VQGYVFDAETRELKSGRTLCIFKITDYTNSILVKMFAREKEDAVLMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEI
KAKTREDTAPEDEKRVELHLHSPMSQMDAVSSIGKLVEQAKKWGHPAIALTDHAVVQSFPDAFAASKKHGVKMIYGLEAN
LVDDGVPIAYNPVHRLLEEETYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIERFERFANPHRPLSATIIELTGITDDM
LKDAPEVEEVIRDFKEWVGDHTLVAHNASFDIGFINVAYKRLLNSEKVQNPVIDTLELGRFLYPEFKNHRLNTLCKKFDI
ELTQHHRAIYDTEATGYLLVKMLKDAAEKNILYHDQLNENMGQSNAYQRSRPYHATLLAVNETGLKNLFKLVSLSHIHYF
YRVPRIPRSQLEKYREGLLIGSACDKGEVFEGMMQKSPEEVEDIASFYDYLEVMPPEVYRHLLQLELVRDEKALKEIIAN
ITKLGEKLNIPVVATGNVHYLNPEDKIYRKILVSSQGGANPLNRHELPNVHFRSTDEMLEAFSFLGEEKAKEIVVKNTRM
ISERIEEIKPIKDDLYTPKIEGADDEIRRMSYEKARSIYGEDLPEIVEKRIEKELKSIIGHGFAVIYLISHKLVKRSLDD
GYLVGSRGSVGSSLVATLTEITEVNPLPPHYVCPDCRHSEFFNDGSVGSGFDLPDKDCPKCGAAYRKDGHDIPFETFLGF
KGDKVPDIDLNFSGEYQPHAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYANDNNLHMRGAEIDRLVQGCTGVKRT
TGQHPGGIIVVPDYMDIYDFSPIQFPADATDSEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDD
PEVMKIFQGTESLGVTEEQIGCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICEL
SEVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKAHAAAYVLMAVRI
AYFKVHHPLLYYAAYFTVRADDFDIETMIKGSTAIRAVMDDINSKGLDASPKEKSLLTVLELALEMCERGFSFQKVDLYR
SSASEFIIDGNSLIPPFNSIPGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTIMEYLERHGCLESLPDQNQLSLF

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI1786381, Length=788, Percent_Identity=23.6040609137056, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI1788149, Length=168, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1786409, Length=171, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 163452; Mature: 163452

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDQLSVNRRQFQILLQQLNVTEDTMIRHLEGGQIIKLTVHKNKKTWHFHFKLRNVLPYQ
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCCCHH
IFERFHSQLTRTFSHIAQVTCSIEAENPSIDEQLVQDYWTRCIQELDGISPPILALLNDQ
HHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
KPKLTGNKILLKTKTDTEASALKKKYSSLIQSSYRTFGFPELQLDTEIFVSDQEIQKFRE
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEECCHHHHHHHH
QKMAEDQERALQALIEMEKQDKEAQDDEAPAGPLQIGYQIKDSEEIRTLDSIMDEERRIT
HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEE
VQGYVFDAETRELKSGRTLCIFKITDYTNSILVKMFAREKEDAVLMKSLKKGMWVKARGS
EEEEEECCHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCC
IQNDTFVRDLVMIANDVNEIKAKTREDTAPEDEKRVELHLHSPMSQMDAVSSIGKLVEQA
CCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
KKWGHPAIALTDHAVVQSFPDAFAASKKHGVKMIYGLEANLVDDGVPIAYNPVHRLLEEE
HHCCCCEEEEEHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHHHCCC
TYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIERFERFANPHRPLSATIIELTGITDDM
CEEEEEECCCCHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHH
LKDAPEVEEVIRDFKEWVGDHTLVAHNASFDIGFINVAYKRLLNSEKVQNPVIDTLELGR
HHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCHHHHCCCHHHHHHHHH
FLYPEFKNHRLNTLCKKFDIELTQHHRAIYDTEATGYLLVKMLKDAAEKNILYHDQLNEN
HHCCHHCCCHHHHHHHHHCCHHHHHCHHHCCCCCHHHHHHHHHHHHHHCCCEEHHHHHCC
MGQSNAYQRSRPYHATLLAVNETGLKNLFKLVSLSHIHYFYRVPRIPRSQLEKYREGLLI
CCCCCCHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEE
GSACDKGEVFEGMMQKSPEEVEDIASFYDYLEVMPPEVYRHLLQLELVRDEKALKEIIAN
ECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ITKLGEKLNIPVVATGNVHYLNPEDKIYRKILVSSQGGANPLNRHELPNVHFRSTDEMLE
HHHHHHHCCCCEEEECCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
AFSFLGEEKAKEIVVKNTRMISERIEEIKPIKDDLYTPKIEGADDEIRRMSYEKARSIYG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
EDLPEIVEKRIEKELKSIIGHGFAVIYLISHKLVKRSLDDGYLVGSRGSVGSSLVATLTE
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHH
ITEVNPLPPHYVCPDCRHSEFFNDGSVGSGFDLPDKDCPKCGAAYRKDGHDIPFETFLGF
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHCCC
KGDKVPDIDLNFSGEYQPHAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYANDNNL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHEEEEECCCCCE
HMRGAEIDRLVQGCTGVKRTTGQHPGGIIVVPDYMDIYDFSPIQFPADATDSEWKTTHFD
EECCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCC
FHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFQGTESLGVTEEQI
HHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHCCCCHHHH
GCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICEL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHH
SEVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKK
HHHHCCCHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHH
IKYMFPKAHAAAYVLMAVRIAYFKVHHPLLYYAAYFTVRADDFDIETMIKGSTAIRAVMD
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCHHHHHHHHH
DINSKGLDASPKEKSLLTVLELALEMCERGFSFQKVDLYRSSASEFIIDGNSLIPPFNSI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCEEECCCCCCCCCCCC
PGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTIMEYLERHGCLESLPDQNQLSLF
CCCCCCHHHHEEEECCCCCCCCHHHHHHHCHHHHHHHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MEDQLSVNRRQFQILLQQLNVTEDTMIRHLEGGQIIKLTVHKNKKTWHFHFKLRNVLPYQ
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCCCHH
IFERFHSQLTRTFSHIAQVTCSIEAENPSIDEQLVQDYWTRCIQELDGISPPILALLNDQ
HHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
KPKLTGNKILLKTKTDTEASALKKKYSSLIQSSYRTFGFPELQLDTEIFVSDQEIQKFRE
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEECCHHHHHHHH
QKMAEDQERALQALIEMEKQDKEAQDDEAPAGPLQIGYQIKDSEEIRTLDSIMDEERRIT
HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEE
VQGYVFDAETRELKSGRTLCIFKITDYTNSILVKMFAREKEDAVLMKSLKKGMWVKARGS
EEEEEECCHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCC
IQNDTFVRDLVMIANDVNEIKAKTREDTAPEDEKRVELHLHSPMSQMDAVSSIGKLVEQA
CCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
KKWGHPAIALTDHAVVQSFPDAFAASKKHGVKMIYGLEANLVDDGVPIAYNPVHRLLEEE
HHCCCCEEEEEHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHHHCCC
TYVVFDVETTGLSAVYDTIIELAAVKVKGGEIIERFERFANPHRPLSATIIELTGITDDM
CEEEEEECCCCHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCHHH
LKDAPEVEEVIRDFKEWVGDHTLVAHNASFDIGFINVAYKRLLNSEKVQNPVIDTLELGR
HHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCHHHHCCCHHHHHHHHH
FLYPEFKNHRLNTLCKKFDIELTQHHRAIYDTEATGYLLVKMLKDAAEKNILYHDQLNEN
HHCCHHCCCHHHHHHHHHCCHHHHHCHHHCCCCCHHHHHHHHHHHHHHCCCEEHHHHHCC
MGQSNAYQRSRPYHATLLAVNETGLKNLFKLVSLSHIHYFYRVPRIPRSQLEKYREGLLI
CCCCCCHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEE
GSACDKGEVFEGMMQKSPEEVEDIASFYDYLEVMPPEVYRHLLQLELVRDEKALKEIIAN
ECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ITKLGEKLNIPVVATGNVHYLNPEDKIYRKILVSSQGGANPLNRHELPNVHFRSTDEMLE
HHHHHHHCCCCEEEECCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
AFSFLGEEKAKEIVVKNTRMISERIEEIKPIKDDLYTPKIEGADDEIRRMSYEKARSIYG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
EDLPEIVEKRIEKELKSIIGHGFAVIYLISHKLVKRSLDDGYLVGSRGSVGSSLVATLTE
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHH
ITEVNPLPPHYVCPDCRHSEFFNDGSVGSGFDLPDKDCPKCGAAYRKDGHDIPFETFLGF
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHCCC
KGDKVPDIDLNFSGEYQPHAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYANDNNL
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHEEEEECCCCCE
HMRGAEIDRLVQGCTGVKRTTGQHPGGIIVVPDYMDIYDFSPIQFPADATDSEWKTTHFD
EECCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCC
FHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFQGTESLGVTEEQI
HHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHCCCCHHHH
GCKTGTLGIPEFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICEL
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHH
SEVIGCRDDIMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKK
HHHHCCCHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHH
IKYMFPKAHAAAYVLMAVRIAYFKVHHPLLYYAAYFTVRADDFDIETMIKGSTAIRAVMD
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHCCHHHHHHHHH
DINSKGLDASPKEKSLLTVLELALEMCERGFSFQKVDLYRSSASEFIIDGNSLIPPFNSI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCEEECCCCCCCCCCCC
PGLGTNAALNIVKAREEGEFLSKEDLQKRGKVSKTIMEYLERHGCLESLPDQNQLSLF
CCCCCCHHHHEEEECCCCCCCCHHHHHHHCHHHHHHHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1901559; 2499883; 1840638; 9384377; 7679775; 2515995; 8491709; 1312503 [H]