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The map label for this gene is frr

Identifier: 52785632

GI number: 52785632

Start: 1825820

End: 1826377

Strand: Direct

Name: frr

Synonym: BLi01873

Alternate gene names: 52785632

Gene position: 1825820-1826377 (Clockwise)

Preceding gene: 52785631

Following gene: 52785633

Centisome position: 43.24

GC content: 45.88

Gene sequence:

>558_bases
GTGTCAACTCAAGTGATGAATGAAACAAAAGAACGGATGCAAAAAGCGATAAGCGCTTATCAGCGCGAATTGGCCACTGT
CCGCGCAGGACGTGCAAATCCGTCATTGCTGGACAAAGTGGCAGTTGAGTATTACGGAGCGCAGACGCCTTTAAACCAGA
TTGCGTCCATTACAGTTCCAGAAGCGCGCATGCTCGTCATCACACCATATGACAAAACGGCGCTCGGCGATATCGAAAAA
GCGATTCAAAAAGCCGACCTCGGTGTAACTCCGTCAAACGACGGCAATATCATCCGGATCACGATCCCTCCTCTAACTGA
GGAGCGCAGAAAAGAGCTTGCCAAACTCGTGAAAAAATATTCGGAAGATGCCAAAGTCGCGGTCCGCAACATCCGCCGCG
ATGCAAATGACGATCTGAAAAAACTAGAGAAAAATGGTGAAATGACTGAGGATGAATTGCGCTCTTCAACGGAAGACGTA
CAAAAGCTGACAGATGAATATGTGTCAAAAATTGATGAGATCACAAAAGATAAAGAGAAAGAAATCATGGAAGTTTAA

Upstream 100 bases:

>100_bases
AACGACATCCCGCTGATCGTCTTTTCTATTATGGAAGAAGGAAATATTAAAAGAGCCGTTTTAGGCGAACAAATCGGTAC
AATCGTAAGGGGGAAATAAC

Downstream 100 bases:

>100_bases
TGAAAAACTCTGTACAATAGATAATAGTGAAAAGACCCTCTCATGTTTACAGGGGGTTTTTTTGTTAATACTGTTGTTAT
CTAGAACGATATAACAGGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSTQVMNETKERMQKAISAYQRELATVRAGRANPSLLDKVAVEYYGAQTPLNQIASITVPEARMLVITPYDKTALGDIEK
AIQKADLGVTPSNDGNIIRITIPPLTEERRKELAKLVKKYSEDAKVAVRNIRRDANDDLKKLEKNGEMTEDELRSSTEDV
QKLTDEYVSKIDEITKDKEKEIMEV

Sequences:

>Translated_185_residues
MSTQVMNETKERMQKAISAYQRELATVRAGRANPSLLDKVAVEYYGAQTPLNQIASITVPEARMLVITPYDKTALGDIEK
AIQKADLGVTPSNDGNIIRITIPPLTEERRKELAKLVKKYSEDAKVAVRNIRRDANDDLKKLEKNGEMTEDELRSSTEDV
QKLTDEYVSKIDEITKDKEKEIMEV
>Mature_184_residues
STQVMNETKERMQKAISAYQRELATVRAGRANPSLLDKVAVEYYGAQTPLNQIASITVPEARMLVITPYDKTALGDIEKA
IQKADLGVTPSNDGNIIRITIPPLTEERRKELAKLVKKYSEDAKVAVRNIRRDANDDLKKLEKNGEMTEDELRSSTEDVQ
KLTDEYVSKIDEITKDKEKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.3333333333333, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI291042689, Length=164, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=48.1081081081081, Blast_Score=184, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_BACLD (Q65JJ6)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_079046.2
- RefSeq:   YP_091461.1
- ProteinModelPortal:   Q65JJ6
- SMR:   Q65JJ6
- STRING:   Q65JJ6
- EnsemblBacteria:   EBBACT00000054271
- EnsemblBacteria:   EBBACT00000060349
- GeneID:   3031066
- GeneID:   3101470
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01873
- KEGG:   bli:BL01240
- NMPDR:   fig|279010.5.peg.2577
- eggNOG:   COG0233
- GeneTree:   EBGT00050000002922
- HOGENOM:   HBG533975
- ProtClustDB:   PRK00083
- BioCyc:   BLIC279010-1:BLI01873-MONOMER
- BioCyc:   BLIC279010:BL01240-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20913; Mature: 20782

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQVMNETKERMQKAISAYQRELATVRAGRANPSLLDKVAVEYYGAQTPLNQIASITVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCC
EARMLVITPYDKTALGDIEKAIQKADLGVTPSNDGNIIRITIPPLTEERRKELAKLVKKY
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
SEDAKVAVRNIRRDANDDLKKLEKNGEMTEDELRSSTEDVQKLTDEYVSKIDEITKDKEK
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMEV
HHHCC
>Mature Secondary Structure 
STQVMNETKERMQKAISAYQRELATVRAGRANPSLLDKVAVEYYGAQTPLNQIASITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCC
EARMLVITPYDKTALGDIEKAIQKADLGVTPSNDGNIIRITIPPLTEERRKELAKLVKKY
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
SEDAKVAVRNIRRDANDDLKKLEKNGEMTEDELRSSTEDVQKLTDEYVSKIDEITKDKEK
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA