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The map label for this gene is yloS [H]

Identifier: 52785560

GI number: 52785560

Start: 1760402

End: 1761046

Strand: Direct

Name: yloS [H]

Synonym: BLi01801

Alternate gene names: 52785560

Gene position: 1760402-1761046 (Clockwise)

Preceding gene: 52785559

Following gene: 52785561

Centisome position: 41.69

GC content: 46.51

Gene sequence:

>645_bases
ATGAAAACGATCAATATTGTAGCGGGAGGCCCCGATCATCTTATTCCCGACTTGCTGCAGTATCAGGCCGGGGATGCGCT
TTGGGTCGGGGTTGACAGAGGCGCTGTCACCCTTTTGGATGCGGGGATCGTGCCTGATGAAGCATTCGGGGATTTTGACA
GCATCACAGACGAGCAAAAAAAAGCGATTGAAAAGGCCGCTCCCCGCCTCCATATTTATCAGGCGGAAAAAGATCAGACG
GATTTGGACCTTGCGTTGAGCTGGGCTGTCGGACAGCGTCCTTCATTTATTAGAATGTTCGGCATTTCGGGAGGCAGAGC
AGACCATTTTCTCGGGAATCTGCACCTTCTTTATACCGCGATGAAGCAAAACGTCAAGACCGTCATGATCGACCGCCAAA
ATACGATCAGCATGCATCCCCCAGGCTCCTATACCGTCATGCATGATCAAACAAAACCGTATATTTCATTCCTGCCGTTT
GCGGAGACGGTAAAAAACCTTTCTCTCGAAGGATTTAAGTATTCTTTAAATAAGTGTCATATTGCTCTCGGTTCGACACT
ATGTATTAGTAACGAACTCATCCATTCACAAGGTGCTTTTTCGTTTTCAGAAGGCATATTAATAATGATAAGAAGCACTG
ATTAA

Upstream 100 bases:

>100_bases
CGATATAAAAGGTGCGCTTGGGTAAGGTTTCCTGATGAAAGAGAGCCGGCTTTCTGCAGCTGCGCTCTTTTTTTAGGGCG
TTCACAGAAAGGATAATGCG

Downstream 100 bases:

>100_bases
ATATCCTGGCGCTTCCGCTCGCTTTGTGTTTGGGATCCGATGTTGAAGGTGGATGCGGTTGCGGACTCTTTGAGGAGGGA
AGGGAATGAAATTTTACACC

Product: YloS

Products: NA

Alternate protein names: TPK; Thiamine diphosphokinase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKTINIVAGGPDHLIPDLLQYQAGDALWVGVDRGAVTLLDAGIVPDEAFGDFDSITDEQKKAIEKAAPRLHIYQAEKDQT
DLDLALSWAVGQRPSFIRMFGISGGRADHFLGNLHLLYTAMKQNVKTVMIDRQNTISMHPPGSYTVMHDQTKPYISFLPF
AETVKNLSLEGFKYSLNKCHIALGSTLCISNELIHSQGAFSFSEGILIMIRSTD

Sequences:

>Translated_214_residues
MKTINIVAGGPDHLIPDLLQYQAGDALWVGVDRGAVTLLDAGIVPDEAFGDFDSITDEQKKAIEKAAPRLHIYQAEKDQT
DLDLALSWAVGQRPSFIRMFGISGGRADHFLGNLHLLYTAMKQNVKTVMIDRQNTISMHPPGSYTVMHDQTKPYISFLPF
AETVKNLSLEGFKYSLNKCHIALGSTLCISNELIHSQGAFSFSEGILIMIRSTD
>Mature_214_residues
MKTINIVAGGPDHLIPDLLQYQAGDALWVGVDRGAVTLLDAGIVPDEAFGDFDSITDEQKKAIEKAAPRLHIYQAEKDQT
DLDLALSWAVGQRPSFIRMFGISGGRADHFLGNLHLLYTAMKQNVKTVMIDRQNTISMHPPGSYTVMHDQTKPYISFLPF
AETVKNLSLEGFKYSLNKCHIALGSTLCISNELIHSQGAFSFSEGILIMIRSTD

Specific function: Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate [H]

COG id: COG1564

COG function: function code H; Thiamine pyrophosphokinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine pyrophosphokinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006282
- InterPro:   IPR007373
- InterPro:   IPR007371 [H]

Pfam domain/function: PF04263 TPK_catalytic [H]

EC number: =2.7.6.2 [H]

Molecular weight: Translated: 23610; Mature: 23610

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTINIVAGGPDHLIPDLLQYQAGDALWVGVDRGAVTLLDAGIVPDEAFGDFDSITDEQK
CCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCHHCCCHHHCCHHHH
KAIEKAAPRLHIYQAEKDQTDLDLALSWAVGQRPSFIRMFGISGGRADHFLGNLHLLYTA
HHHHHCCCEEEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
MKQNVKTVMIDRQNTISMHPPGSYTVMHDQTKPYISFLPFAETVKNLSLEGFKYSLNKCH
HHCCCEEEEEECCCEEEECCCCCEEEEECCCCCEEEECCHHHHHHHCCCCCEEEECCEEE
IALGSTLCISNELIHSQGAFSFSEGILIMIRSTD
EEECCEEEECHHHHHCCCCCEECCCEEEEEEECC
>Mature Secondary Structure
MKTINIVAGGPDHLIPDLLQYQAGDALWVGVDRGAVTLLDAGIVPDEAFGDFDSITDEQK
CCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCHHCCCHHHCCHHHH
KAIEKAAPRLHIYQAEKDQTDLDLALSWAVGQRPSFIRMFGISGGRADHFLGNLHLLYTA
HHHHHCCCEEEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
MKQNVKTVMIDRQNTISMHPPGSYTVMHDQTKPYISFLPFAETVKNLSLEGFKYSLNKCH
HHCCCEEEEEECCCEEEECCCCCEEEEECCCCCEEEECCHHHHHHHCCCCCEEEECCEEE
IALGSTLCISNELIHSQGAFSFSEGILIMIRSTD
EEECCEEEECHHHHHCCCCCEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]