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The map label for this gene is ylnD [H]

Identifier: 52785541

GI number: 52785541

Start: 1739686

End: 1740459

Strand: Direct

Name: ylnD [H]

Synonym: BLi01782

Alternate gene names: 52785541

Gene position: 1739686-1740459 (Clockwise)

Preceding gene: 52785540

Following gene: 52785542

Centisome position: 41.2

GC content: 48.84

Gene sequence:

>774_bases
ATGGGGAAAGTATATATCGTTGGGGCAGGTCCTGGAGACCCCGATTTACTGACGATCAAAGCTTTAAAAGCCATCCAGAC
AGCCGATGTCATTTTGTATGACAGGCTTGTGAATAAACAGATTTTACAGCACGCCAAGGAGGGAGCGGATCTCATCTACT
GCGGAAAGCTTCCGGACTACCACATGATGAAGCAGGAAACGATCAATCATTTTCTCGTCAAGTATGCGAAAAAAGGGAAA
ACCGTTGTCAGACTGAAAGGCGGCGATCCTTTCGTATTCGGCAGAGGCGGCGAGGAAGCGCAAACCCTCGCTGAGCACGG
GGTTGCTTTTGAAATCGTGCCGGGAATCACCTCGGGAATAGCTGCCGCTGCTTATGCGGGCATTCCGGTGACACACCGGG
AAGCGAGTTCAAACGTTGCTTTCGTGACAGGCCATTATCAAAAAGAAGAAAACTTTGAAGAGAAGTGGAAAGCGTTAGCC
ACAGGGATCGATACGCTTGTCATTTATATGGGGATTAAAAACGTGAAGCAAATTGAAAGGCTTCTGATCGAAAACGGCAG
AGACCCGTCAACGCCAGCCGCTTTCATCCATTGGGGAACGACAGACAAACAAAAAACGGTGCTTTGCACGGTTGAAACGC
TTGCCGGTACAGTCGAAAGCGAAAAGATTGAAAACCCGAGCCTGATTGTCATCGGGGATGTCGTTCAATTCAGCTCGCAG
TTAAGCTGGTTTGAACCTGAGCTGAAAGATCCGGCATTAAGCGAGGCGCTTTAA

Upstream 100 bases:

>100_bases
AAAACGTTTGGTTTTTGTGATATTTTCAGGCACCAAACGCTTTCTTTATGATTTATAATGAATTGAAGAAGACGTTGATC
AGATCGGGGGGAGATCTAAG

Downstream 100 bases:

>100_bases
TATGAAACAAGCGATTTTATATATCGGCCATGGAAGCCGTCTGAAAAGAGCCCAAACAGAAGCAGCCGCTTTTTTGGAGA
GCTGCAAAGAAAACATGTCC

Product: YlnD

Products: NA

Alternate protein names: Urogen III methylase; SUMT; Uroporphyrinogen III methylase; UROM [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MGKVYIVGAGPGDPDLLTIKALKAIQTADVILYDRLVNKQILQHAKEGADLIYCGKLPDYHMMKQETINHFLVKYAKKGK
TVVRLKGGDPFVFGRGGEEAQTLAEHGVAFEIVPGITSGIAAAAYAGIPVTHREASSNVAFVTGHYQKEENFEEKWKALA
TGIDTLVIYMGIKNVKQIERLLIENGRDPSTPAAFIHWGTTDKQKTVLCTVETLAGTVESEKIENPSLIVIGDVVQFSSQ
LSWFEPELKDPALSEAL

Sequences:

>Translated_257_residues
MGKVYIVGAGPGDPDLLTIKALKAIQTADVILYDRLVNKQILQHAKEGADLIYCGKLPDYHMMKQETINHFLVKYAKKGK
TVVRLKGGDPFVFGRGGEEAQTLAEHGVAFEIVPGITSGIAAAAYAGIPVTHREASSNVAFVTGHYQKEENFEEKWKALA
TGIDTLVIYMGIKNVKQIERLLIENGRDPSTPAAFIHWGTTDKQKTVLCTVETLAGTVESEKIENPSLIVIGDVVQFSSQ
LSWFEPELKDPALSEAL
>Mature_256_residues
GKVYIVGAGPGDPDLLTIKALKAIQTADVILYDRLVNKQILQHAKEGADLIYCGKLPDYHMMKQETINHFLVKYAKKGKT
VVRLKGGDPFVFGRGGEEAQTLAEHGVAFEIVPGITSGIAAAAYAGIPVTHREASSNVAFVTGHYQKEENFEEKWKALAT
GIDTLVIYMGIKNVKQIERLLIENGRDPSTPAAFIHWGTTDKQKTVLCTVETLAGTVESEKIENPSLIVIGDVVQFSSQL
SWFEPELKDPALSEAL

Specific function: Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin [H]

COG id: COG0007

COG function: function code H; Uroporphyrinogen-III methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=243, Percent_Identity=45.679012345679, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6322922, Length=242, Percent_Identity=31.404958677686, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006366
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 28081; Mature: 27949

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVYIVGAGPGDPDLLTIKALKAIQTADVILYDRLVNKQILQHAKEGADLIYCGKLPDY
CCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
HMMKQETINHFLVKYAKKGKTVVRLKGGDPFVFGRGGEEAQTLAEHGVAFEIVPGITSGI
HHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHHHCCCEEEECCCCHHHH
AAAAYAGIPVTHREASSNVAFVTGHYQKEENFEEKWKALATGIDTLVIYMGIKNVKQIER
HHHHHCCCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIENGRDPSTPAAFIHWGTTDKQKTVLCTVETLAGTVESEKIENPSLIVIGDVVQFSSQ
HHHHCCCCCCCCEEEEEECCCCCCCEEEEEEHHHHCCHHHHCCCCCCEEEEEHHHHHHHC
LSWFEPELKDPALSEAL
CCCCCCCCCCCCHHHCC
>Mature Secondary Structure 
GKVYIVGAGPGDPDLLTIKALKAIQTADVILYDRLVNKQILQHAKEGADLIYCGKLPDY
CEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
HMMKQETINHFLVKYAKKGKTVVRLKGGDPFVFGRGGEEAQTLAEHGVAFEIVPGITSGI
HHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHHHCCCEEEECCCCHHHH
AAAAYAGIPVTHREASSNVAFVTGHYQKEENFEEKWKALATGIDTLVIYMGIKNVKQIER
HHHHHCCCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIENGRDPSTPAAFIHWGTTDKQKTVLCTVETLAGTVESEKIENPSLIVIGDVVQFSSQ
HHHHCCCCCCCCEEEEEECCCCCCCEEEEEEHHHHCCHHHHCCCCCCEEEEEHHHHHHHC
LSWFEPELKDPALSEAL
CCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]