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The map label for this gene is cysC

Identifier: 52785540

GI number: 52785540

Start: 1738941

End: 1739534

Strand: Direct

Name: cysC

Synonym: BLi01781

Alternate gene names: 52785540

Gene position: 1738941-1739534 (Clockwise)

Preceding gene: 52785539

Following gene: 52785541

Centisome position: 41.18

GC content: 48.15

Gene sequence:

>594_bases
TTGGTAAATAAAGATATTGTCTGGCATGAAGCGTCCATTACAAAACGGGAATATCATGAGAAAAATCAACATAAAAGCTC
AATCATTTGGCTGACGGGCTTAAGCGGTTCAGGAAAATCAACGATTGCCAACGCCGCTGCGCGTGAGTTGTTTGCACAAG
GCTACCAGGTCACGGTGCTTGACGGCGACAACGTCAGGCACGGGCTGAACAAGGACCTCGGGTTTTCCGATGAAGACCGG
AAGGAAAACATCCGCCGGATCGGCGAGGTTGCGAAGCTCTTTGTCGAACAGGGGACGATCGTCATTACGGCGTTCATTTC
TCCTTTTAAAGAAGATCGCGGGCTTGTCAGACAGCTTGTCGAGGAAGATGAGTTTCACGAAGTCTATGTGAAATGCGATT
TGGCGACGTGTGAAGAGCGCGACCCGAAAGGCTTGTACAAAAAAGCGAGAAACGGAGAAATTCCATTTTTCACAGGGATC
GATTCGCCTTATGAAGAGCCTGAAACGCCTGAGCTTGTTCTTGATACAGGCGCACATAACCGGGAAGAGTGCAAAAACCA
GCTCGTCCAATACGTGAAAGATCAAACGAAATAA

Upstream 100 bases:

>100_bases
AGAAGCGGCGAGTTCCCGCCGAGCACATTCAGCCGTCCCGAAGTTATTCAAACATTAATCAAAGGCTTAGCGGCCGGGGT
TTCTTAAGGGGGAGCATCTC

Downstream 100 bases:

>100_bases
AATGCGGGTGAATAGGAAAGTGCGGCGCATGCACTTTCCTATTTCATAAAGAAAACGTTTGGTTTTTGTGATATTTTCAG
GCACCAAACGCTTTCTTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MVNKDIVWHEASITKREYHEKNQHKSSIIWLTGLSGSGKSTIANAAARELFAQGYQVTVLDGDNVRHGLNKDLGFSDEDR
KENIRRIGEVAKLFVEQGTIVITAFISPFKEDRGLVRQLVEEDEFHEVYVKCDLATCEERDPKGLYKKARNGEIPFFTGI
DSPYEEPETPELVLDTGAHNREECKNQLVQYVKDQTK

Sequences:

>Translated_197_residues
MVNKDIVWHEASITKREYHEKNQHKSSIIWLTGLSGSGKSTIANAAARELFAQGYQVTVLDGDNVRHGLNKDLGFSDEDR
KENIRRIGEVAKLFVEQGTIVITAFISPFKEDRGLVRQLVEEDEFHEVYVKCDLATCEERDPKGLYKKARNGEIPFFTGI
DSPYEEPETPELVLDTGAHNREECKNQLVQYVKDQTK
>Mature_197_residues
MVNKDIVWHEASITKREYHEKNQHKSSIIWLTGLSGSGKSTIANAAARELFAQGYQVTVLDGDNVRHGLNKDLGFSDEDR
KENIRRIGEVAKLFVEQGTIVITAFISPFKEDRGLVRQLVEEDEFHEVYVKCDLATCEERDPKGLYKKARNGEIPFFTGI
DSPYEEPETPELVLDTGAHNREECKNQLVQYVKDQTK

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=173, Percent_Identity=53.1791907514451, Blast_Score=186, Evalue=8e-48,
Organism=Homo sapiens, GI34447231, Length=173, Percent_Identity=53.1791907514451, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI62912492, Length=173, Percent_Identity=53.1791907514451, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI1789107, Length=195, Percent_Identity=52.8205128205128, Blast_Score=205, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17542422, Length=201, Percent_Identity=47.7611940298507, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322852, Length=190, Percent_Identity=50.5263157894737, Blast_Score=182, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24667032, Length=173, Percent_Identity=47.3988439306358, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24667028, Length=173, Percent_Identity=47.3988439306358, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24667036, Length=173, Percent_Identity=47.3988439306358, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24667040, Length=173, Percent_Identity=47.3988439306358, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI116007838, Length=173, Percent_Identity=47.3988439306358, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24667044, Length=173, Percent_Identity=47.3988439306358, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_BACLD (Q65JT8)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078954.1
- RefSeq:   YP_091369.1
- HSSP:   Q12657
- ProteinModelPortal:   Q65JT8
- SMR:   Q65JT8
- STRING:   Q65JT8
- EnsemblBacteria:   EBBACT00000056161
- EnsemblBacteria:   EBBACT00000060592
- GeneID:   3030936
- GeneID:   3099106
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01781
- KEGG:   bli:BL02285
- NMPDR:   fig|279010.5.peg.1723
- eggNOG:   COG0529
- GeneTree:   EBGT00050000001911
- HOGENOM:   HBG309946
- OMA:   IKRDPKG
- ProtClustDB:   CLSK887283
- BioCyc:   BLIC279010-1:BLI01781-MONOMER
- BioCyc:   BLIC279010:BL02285-MONOMER
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 22456; Mature: 22456

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: ACT_SITE 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKDIVWHEASITKREYHEKNQHKSSIIWLTGLSGSGKSTIANAAARELFAQGYQVTVL
CCCCCEEEECHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEE
DGDNVRHGLNKDLGFSDEDRKENIRRIGEVAKLFVEQGTIVITAFISPFKEDRGLVRQLV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHH
EEDEFHEVYVKCDLATCEERDPKGLYKKARNGEIPFFTGIDSPYEEPETPELVLDTGAHN
CCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEECCCCC
REECKNQLVQYVKDQTK
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNKDIVWHEASITKREYHEKNQHKSSIIWLTGLSGSGKSTIANAAARELFAQGYQVTVL
CCCCCEEEECHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEE
DGDNVRHGLNKDLGFSDEDRKENIRRIGEVAKLFVEQGTIVITAFISPFKEDRGLVRQLV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHH
EEDEFHEVYVKCDLATCEERDPKGLYKKARNGEIPFFTGIDSPYEEPETPELVLDTGAHN
CCCCCEEEEEEEECCCCCCCCCHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEECCCCC
REECKNQLVQYVKDQTK
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA