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The map label for this gene is murG

Identifier: 52785498

GI number: 52785498

Start: 1695247

End: 1696347

Strand: Direct

Name: murG

Synonym: BLi01739

Alternate gene names: 52785498

Gene position: 1695247-1696347 (Clockwise)

Preceding gene: 52785497

Following gene: 52785499

Centisome position: 40.15

GC content: 48.05

Gene sequence:

>1101_bases
ATGCGGATTGTTGTTAGCGGAGGCGGAACGGGCGGCCATATTTACCCCGCCCTTGCGTTTATTAAAGAAGTGAAACGGCA
TCACGAAGATGTTGAGTTTTTATATATCGGAACCGAAAAAGGCCTGGAGAAAAATATCGTCGAGCGGGAAGGGATCCCTT
TCAAAGCGATTGAAATTACGGGTTTTAAAAGAAAACTTTCATTTGAAAACGTCAAAACCGTCATGCGCTTTTTAAAGGGT
GTAAAAGAATGCAAAGAAGAATTAAAACGGTTCAAGCCGGATGCCGTGATCGGCACGGGCGGCTACGTGTGCGGCCCCGT
CGTATACGCCGCTTCAAAACTGGGGATTCCGACGATTATCCACGAACAAAACAGCCTTCCCGGACTCACCAATAAGTTTT
TATCCAAATATGTTGATAAGGTAGCGATTTGTTTTGATGAAGCGAAAACACATTTTCCTGCAGAAAAAGTTGTTTTTACA
GGAAACCCGAGGGCGTCTGAAGTCGTCTCTATAAAAGGGGGCCGTTCCCTGACCGCTTTGGGTCTTGCAGAGGGCAAAAA
AACGGTCCTTATTTTCGGAGGCAGCCGCGGTGCCGCTCCGATCAATGAAGCGGTCATTGCGATGCAAAACGAATTAAAAA
AGCGGGATTACCAGGTTCTTTATGTCACAGGGGAAGTTCACTATGATAAAGTCACAGCTGCGCTTGAAAAAGAAGGCGCC
GCTCCGAATATGGTCGTCCAGCCGTTTCTCCATCAAATGCCCGAGTACTTAAAAGCGTTCGATGTCGTCGTGGGCCGCGC
AGGGGCAACGACAATAGCGGAAATCACCGCGCTCGGCATTCCAAGCGTTCTGATTCCGAGTCCGTATGTTACGGCCAACC
ACCAGGAAGTAAACGCACGCTCACTCGGGGAGCAGAACGCCGCTGTCGTTTTAAAAGAATCAGAGCTTAATGGAGACCGC
TTAATTCAGGCGATCGATCATATTTTACAAGACGAAAAGACGTTGGAAGAGATGAAGATCCGCGCGAAATCGCTTGGCGT
GCCGGACGCTGCGGAACGCTTGTACAATGTGCTGAAAGAATTGAAACATCATGCAAAATGA

Upstream 100 bases:

>100_bases
TGAATGTCAGCAGGTATTCTAGATACTAGATTTTGGCGATAACCCTGTTGCGAGATAGCAGGGTTATCGGCGTGTACATA
AGGATTAAGGGGGAGAACAG

Downstream 100 bases:

>100_bases
TAAGACAGAAGGATTGTGGAGGTTTTCGATGGATAAGGTGATACAAGAATTAAAAGAACTTGAAGTCGGCAAAGTTCTGG
AAAACGAGCCGCTCAGCAAC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRIVVSGGGTGGHIYPALAFIKEVKRHHEDVEFLYIGTEKGLEKNIVEREGIPFKAIEITGFKRKLSFENVKTVMRFLKG
VKECKEELKRFKPDAVIGTGGYVCGPVVYAASKLGIPTIIHEQNSLPGLTNKFLSKYVDKVAICFDEAKTHFPAEKVVFT
GNPRASEVVSIKGGRSLTALGLAEGKKTVLIFGGSRGAAPINEAVIAMQNELKKRDYQVLYVTGEVHYDKVTAALEKEGA
APNMVVQPFLHQMPEYLKAFDVVVGRAGATTIAEITALGIPSVLIPSPYVTANHQEVNARSLGEQNAAVVLKESELNGDR
LIQAIDHILQDEKTLEEMKIRAKSLGVPDAAERLYNVLKELKHHAK

Sequences:

>Translated_366_residues
MRIVVSGGGTGGHIYPALAFIKEVKRHHEDVEFLYIGTEKGLEKNIVEREGIPFKAIEITGFKRKLSFENVKTVMRFLKG
VKECKEELKRFKPDAVIGTGGYVCGPVVYAASKLGIPTIIHEQNSLPGLTNKFLSKYVDKVAICFDEAKTHFPAEKVVFT
GNPRASEVVSIKGGRSLTALGLAEGKKTVLIFGGSRGAAPINEAVIAMQNELKKRDYQVLYVTGEVHYDKVTAALEKEGA
APNMVVQPFLHQMPEYLKAFDVVVGRAGATTIAEITALGIPSVLIPSPYVTANHQEVNARSLGEQNAAVVLKESELNGDR
LIQAIDHILQDEKTLEEMKIRAKSLGVPDAAERLYNVLKELKHHAK
>Mature_366_residues
MRIVVSGGGTGGHIYPALAFIKEVKRHHEDVEFLYIGTEKGLEKNIVEREGIPFKAIEITGFKRKLSFENVKTVMRFLKG
VKECKEELKRFKPDAVIGTGGYVCGPVVYAASKLGIPTIIHEQNSLPGLTNKFLSKYVDKVAICFDEAKTHFPAEKVVFT
GNPRASEVVSIKGGRSLTALGLAEGKKTVLIFGGSRGAAPINEAVIAMQNELKKRDYQVLYVTGEVHYDKVTAALEKEGA
APNMVVQPFLHQMPEYLKAFDVVVGRAGATTIAEITALGIPSVLIPSPYVTANHQEVNARSLGEQNAAVVLKESELNGDR
LIQAIDHILQDEKTLEEMKIRAKSLGVPDAAERLYNVLKELKHHAK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=357, Percent_Identity=33.6134453781513, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_BACLD (Q65JY0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078915.1
- RefSeq:   YP_091327.1
- ProteinModelPortal:   Q65JY0
- STRING:   Q65JY0
- EnsemblBacteria:   EBBACT00000058218
- EnsemblBacteria:   EBBACT00000061294
- GeneID:   3030888
- GeneID:   3099670
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01739
- KEGG:   bli:BL02243
- NMPDR:   fig|279010.5.peg.1586
- eggNOG:   COG0707
- GeneTree:   EBGT00050000001194
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   BLIC279010-1:BLI01739-MONOMER
- BioCyc:   BLIC279010:BL02243-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40084; Mature: 40084

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVVSGGGTGGHIYPALAFIKEVKRHHEDVEFLYIGTEKGLEKNIVEREGIPFKAIEIT
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCEEEEEEE
GFKRKLSFENVKTVMRFLKGVKECKEELKRFKPDAVIGTGGYVCGPVVYAASKLGIPTII
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCEEE
HEQNSLPGLTNKFLSKYVDKVAICFDEAKTHFPAEKVVFTGNPRASEVVSIKGGRSLTAL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCEEEEE
GLAEGKKTVLIFGGSRGAAPINEAVIAMQNELKKRDYQVLYVTGEVHYDKVTAALEKEGA
EECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCEEHHHHHHHHHHCCC
APNMVVQPFLHQMPEYLKAFDVVVGRAGATTIAEITALGIPSVLIPSPYVTANHQEVNAR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCEECCCCCCCHH
SLGEQNAAVVLKESELNGDRLIQAIDHILQDEKTLEEMKIRAKSLGVPDAAERLYNVLKE
HCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LKHHAK
HHHHCC
>Mature Secondary Structure
MRIVVSGGGTGGHIYPALAFIKEVKRHHEDVEFLYIGTEKGLEKNIVEREGIPFKAIEIT
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCEEEEEEE
GFKRKLSFENVKTVMRFLKGVKECKEELKRFKPDAVIGTGGYVCGPVVYAASKLGIPTII
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCEEE
HEQNSLPGLTNKFLSKYVDKVAICFDEAKTHFPAEKVVFTGNPRASEVVSIKGGRSLTAL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCEEEEE
GLAEGKKTVLIFGGSRGAAPINEAVIAMQNELKKRDYQVLYVTGEVHYDKVTAALEKEGA
EECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCEEHHHHHHHHHHCCC
APNMVVQPFLHQMPEYLKAFDVVVGRAGATTIAEITALGIPSVLIPSPYVTANHQEVNAR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCEECCCCCCCHH
SLGEQNAAVVLKESELNGDRLIQAIDHILQDEKTLEEMKIRAKSLGVPDAAERLYNVLKE
HCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LKHHAK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA