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The map label for this gene is moeA [H]

Identifier: 52785402

GI number: 52785402

Start: 1601739

End: 1603031

Strand: Direct

Name: moeA [H]

Synonym: BLi01641

Alternate gene names: 52785402

Gene position: 1601739-1603031 (Clockwise)

Preceding gene: 52785401

Following gene: 52785403

Centisome position: 37.93

GC content: 51.2

Gene sequence:

>1293_bases
ATGATTGAAAAAAGAACGCCCATTCCAGTTTTTGAAGCCGCTGCGCGTGTCTCTCAGCACCAGAAGCTGGGAGATGCAGA
GTGGATTCACCTTGAGGAGAGTCTCCATAGATTTTTAGCCGAAGATGTCAAGGCTGATCACGATGTACCCGCTTTTGACC
GTTCGCCATACGACGGCTTTGCTGTCCGAGCATGCGATACAGCCGGTGCTTCGGGGGAAAATCCGCTGCAATTCGAGGTG
GTTGATCACATTGGAGCCGGGGCCGTATCGGATAAAAAGCTGGGTTCTTTTCAAGCCGTCAGAATTATGACGGGAGCGCA
GATTCCGGAGGGCGCTGATGCGGTAGTCATGCTTGAGCTGACAAAAACCTTCTCGGAAGACGGCAAAAACTATATGGTGT
TGAAGCGCTCACTACAGCCGGGAGAAAATATATCAAAAACCGGAGAAGATGCGAGAAAAGGATCAGTTCTTGTGAAAAAA
GGAACCCGGATAACGCCGGGTGTTGTCGCTTTGCTTGCAACATTCGGATATGCAGCGGTTCCTGCAGTCAAAAAGCCTGT
GGTAGGCATCATTGCCACCGGGACGGAGCTTCTGAATGTCAGCGATCCTCTTGTTCCCGGAAAAATCCGCAACAGCAATG
CAGGCATGGCGGCCGCTCAGGTTGAAGAATCAGGCGGAAAACCCCTTTATTTAGGAAAGATTTCTGATCAATTTGACGAA
AGCTTTGCAGCGGTGGAAAAAGCTTTGGACAAGGTGGATTTTCTGATTACGACCGGAGGGGTATCCGTAGGGGACTTTGA
TTTTCTGCCGGCAATTTACGAAAAGCTCGGTGCCGAGGTCCTGTTTAATAAAGTGGCGATGCGTCCCGGAAGTGTAACGA
CGGTCGCTCAATTAAACGGCAAATTGCTGTTTGGGCTGTCCGGGAACCCGTCAGCCTGCTTCGTTGGATTTGAGCTTTTC
GTCAAGCCGTCCCTGCGCACCTGGCTGCATCATCCGAAGCCGTATTCTTTATGTGCAGAAGCGGTTTTAGCCAAGGATTT
TCCAAAACCTAACCCGTTTACGAGGTTTGTCCGCTCGTTTGTATCCATTCAAGACGGCGCGCTTCAGGCGGAGCCTGTCG
GTCTGGATAAATCGAGCGCCGTAACGTCTCTTGCAGATGCCAATGCGCTGATGGTTTTGCCGGGCGGAACGAGAGGCTTT
GAAGCCGGGGCAAGAGTGCATGTTCTTTTATACCGGGATGAGAACGGAAGTGAACAGCTGTGGCCGCACATTTTCCAATC
CTCCAGATCGTAG

Upstream 100 bases:

>100_bases
AACGATGGAAGAGCCCTTGTTCACGGCACAAATGATATAAAAGAAGCCAACTCCATATTGGCGAGAGTCATCGGAATGTA
ACAACAGGAGGTTTTTTTAA

Downstream 100 bases:

>100_bases
GGTACCAAAACAGCGGCAAAACGACGTTCGTTGAAAAATTGGCGGGAAAGCTCGATCAGCTAGGAGTCAATGTTGGCTGT
CTGAAACACCACGGACATGG

Product: hypothetical protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MIEKRTPIPVFEAAARVSQHQKLGDAEWIHLEESLHRFLAEDVKADHDVPAFDRSPYDGFAVRACDTAGASGENPLQFEV
VDHIGAGAVSDKKLGSFQAVRIMTGAQIPEGADAVVMLELTKTFSEDGKNYMVLKRSLQPGENISKTGEDARKGSVLVKK
GTRITPGVVALLATFGYAAVPAVKKPVVGIIATGTELLNVSDPLVPGKIRNSNAGMAAAQVEESGGKPLYLGKISDQFDE
SFAAVEKALDKVDFLITTGGVSVGDFDFLPAIYEKLGAEVLFNKVAMRPGSVTTVAQLNGKLLFGLSGNPSACFVGFELF
VKPSLRTWLHHPKPYSLCAEAVLAKDFPKPNPFTRFVRSFVSIQDGALQAEPVGLDKSSAVTSLADANALMVLPGGTRGF
EAGARVHVLLYRDENGSEQLWPHIFQSSRS

Sequences:

>Translated_430_residues
MIEKRTPIPVFEAAARVSQHQKLGDAEWIHLEESLHRFLAEDVKADHDVPAFDRSPYDGFAVRACDTAGASGENPLQFEV
VDHIGAGAVSDKKLGSFQAVRIMTGAQIPEGADAVVMLELTKTFSEDGKNYMVLKRSLQPGENISKTGEDARKGSVLVKK
GTRITPGVVALLATFGYAAVPAVKKPVVGIIATGTELLNVSDPLVPGKIRNSNAGMAAAQVEESGGKPLYLGKISDQFDE
SFAAVEKALDKVDFLITTGGVSVGDFDFLPAIYEKLGAEVLFNKVAMRPGSVTTVAQLNGKLLFGLSGNPSACFVGFELF
VKPSLRTWLHHPKPYSLCAEAVLAKDFPKPNPFTRFVRSFVSIQDGALQAEPVGLDKSSAVTSLADANALMVLPGGTRGF
EAGARVHVLLYRDENGSEQLWPHIFQSSRS
>Mature_430_residues
MIEKRTPIPVFEAAARVSQHQKLGDAEWIHLEESLHRFLAEDVKADHDVPAFDRSPYDGFAVRACDTAGASGENPLQFEV
VDHIGAGAVSDKKLGSFQAVRIMTGAQIPEGADAVVMLELTKTFSEDGKNYMVLKRSLQPGENISKTGEDARKGSVLVKK
GTRITPGVVALLATFGYAAVPAVKKPVVGIIATGTELLNVSDPLVPGKIRNSNAGMAAAQVEESGGKPLYLGKISDQFDE
SFAAVEKALDKVDFLITTGGVSVGDFDFLPAIYEKLGAEVLFNKVAMRPGSVTTVAQLNGKLLFGLSGNPSACFVGFELF
VKPSLRTWLHHPKPYSLCAEAVLAKDFPKPNPFTRFVRSFVSIQDGALQAEPVGLDKSSAVTSLADANALMVLPGGTRGF
EAGARVHVLLYRDENGSEQLWPHIFQSSRS

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=386, Percent_Identity=35.4922279792746, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI66932975, Length=386, Percent_Identity=35.4922279792746, Blast_Score=205, Evalue=5e-53,
Organism=Escherichia coli, GI1787049, Length=309, Percent_Identity=36.5695792880259, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25147659, Length=379, Percent_Identity=32.4538258575198, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17562606, Length=364, Percent_Identity=25.8241758241758, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17136978, Length=380, Percent_Identity=30.7894736842105, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24638841, Length=380, Percent_Identity=30.7894736842105, Blast_Score=134, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 46068; Mature: 46068

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKRTPIPVFEAAARVSQHQKLGDAEWIHLEESLHRFLAEDVKADHDVPAFDRSPYDGF
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
AVRACDTAGASGENPLQFEVVDHIGAGAVSDKKLGSFQAVRIMTGAQIPEGADAVVMLEL
EEEEECCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEE
TKTFSEDGKNYMVLKRSLQPGENISKTGEDARKGSVLVKKGTRITPGVVALLATFGYAAV
HHHHHHCCCEEEEEEECCCCCCCCHHCCCHHHCCCEEEECCCCCCHHHHHHHHHHCHHHC
PAVKKPVVGIIATGTELLNVSDPLVPGKIRNSNAGMAAAQVEESGGKPLYLGKISDQFDE
CHHHCCCEEEEECCCEEECCCCCCCCCEECCCCCCCEEEEHHHCCCCEEEEECCCHHHHH
SFAAVEKALDKVDFLITTGGVSVGDFDFLPAIYEKLGAEVLFNKVAMRPGSVTTVAQLNG
HHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEECCC
KLLFGLSGNPSACFVGFELFVKPSLRTWLHHPKPYSLCAEAVLAKDFPKPNPFTRFVRSF
EEEEEECCCCCEEEEEEEEEECCCHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
VSIQDGALQAEPVGLDKSSAVTSLADANALMVLPGGTRGFEAGARVHVLLYRDENGSEQL
HHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCHHH
WPHIFQSSRS
HHHHHHCCCC
>Mature Secondary Structure
MIEKRTPIPVFEAAARVSQHQKLGDAEWIHLEESLHRFLAEDVKADHDVPAFDRSPYDGF
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
AVRACDTAGASGENPLQFEVVDHIGAGAVSDKKLGSFQAVRIMTGAQIPEGADAVVMLEL
EEEEECCCCCCCCCCEEEEEEHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEE
TKTFSEDGKNYMVLKRSLQPGENISKTGEDARKGSVLVKKGTRITPGVVALLATFGYAAV
HHHHHHCCCEEEEEEECCCCCCCCHHCCCHHHCCCEEEECCCCCCHHHHHHHHHHCHHHC
PAVKKPVVGIIATGTELLNVSDPLVPGKIRNSNAGMAAAQVEESGGKPLYLGKISDQFDE
CHHHCCCEEEEECCCEEECCCCCCCCCEECCCCCCCEEEEHHHCCCCEEEEECCCHHHHH
SFAAVEKALDKVDFLITTGGVSVGDFDFLPAIYEKLGAEVLFNKVAMRPGSVTTVAQLNG
HHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEECCC
KLLFGLSGNPSACFVGFELFVKPSLRTWLHHPKPYSLCAEAVLAKDFPKPNPFTRFVRSF
EEEEEECCCCCEEEEEEEEEECCCHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
VSIQDGALQAEPVGLDKSSAVTSLADANALMVLPGGTRGFEAGARVHVLLYRDENGSEQL
HHHCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCHHH
WPHIFQSSRS
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]