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The map label for this gene is ykuR

Identifier: 52785394

GI number: 52785394

Start: 1594810

End: 1595934

Strand: Direct

Name: ykuR

Synonym: BLi01633

Alternate gene names: 52785394

Gene position: 1594810-1595934 (Clockwise)

Preceding gene: 52785393

Following gene: 52785395

Centisome position: 37.77

GC content: 51.47

Gene sequence:

>1125_bases
ATGAAATTGGACGAATTAGCAGCGATTCGCAGAGATCTGCACCAAATTCCTGAACTCGGTTTTCAGGAATATAAGACACA
GGCTTATCTTTTGAACCACTTAGCAAAGCATCCGGAAGGACGGATTGAAATTGAAAAGTGGAGAACCGGACTGTTTGTAA
AGGTTAAAGGGACGGCCCCTGAAAAGATTTTGGCGTACAGGGCGGATATGGACGGGCTCTCTATTCGGGAAGATACCGGA
TATTCTTTTTCTTCCGTTCATCAGGACAGGATGCATGCGTGCGGGCATGATTTCCACATGACGATTGCCCTCGGCATCAT
CGATCATTTCGTCCGCCACCCGGTTAAACAAGATCTGCTGTTTTTGTTCCAGCCGGCTGAGGAAGGACCGGGCGGCGCTG
AGCCGATGCTTGAAAGCGACTTGTTTAAAAAGTGGGAGCCGAGCATGATCACAGCGCTGCACATCGCGCCTGAACTCCCG
GTCGGAACGATCGGAACGAAAAGCGGGCTGCTCTTTGCCAATACGTCGGAGCTCGTAATCGAACTTGAAGGAAAGGGCGG
GCATGCCGCATATCCCCACCTTGCAGAAGATATGGTGGTCGCGGCCAGTTCGCTCGTTACGCAAATGCAGTCGATCGTAG
CCAGGAATGTCGATCCGCTGGACAGTGCTGTTATTACCATCGGGACGATTACAGGCGGATCGGCACAAAACATCATCGCT
CAGGAAGCAAGGCTTGAAGGGACGATCAGGACGCTGTCCCCAGCGTCAATGGAACAGGTGAAGAAAAGGATCGAGGCCAT
GGTTCGGGGCCTGGAAACGGCTTATCAATGCAGCGGTAAAGTCAGCTATCCTGCAGCATATTATCAGGTCTGCAATTCAA
GCGATTTAGTCGAAGACTTTATGCAGTTCGTTTCTGAAAACGGCCTTGCAGAGGTCGTCCGTTCAAAAGAAGCGATGACA
GGGGAGGACTTCGGCTATATGCTGAAAAAGTATCCGGGCTTCATGTTTTGGCTCGGCGTCGATTCACCTTACGGGCTTCA
CCACGCCAAGCTGCAGCCGAAAGAGGAAGCGCTTGAAACGGCAGTCCGCGTCATGACGGCTTATTTCTCTTCCAAAGCCA
ATTAG

Upstream 100 bases:

>100_bases
AGAAATCAAACAGGAATTGCGCCAGCTTTAAGAAGCGGCAGCGAAAAGTGCGTGGATGTGACAATCCACGCATTTTCGCA
TCGCCGGGGAGGTTAGAAAG

Downstream 100 bases:

>100_bases
ATAAAGCGGCTGGTATAAAAAATCGGCAAACGTGGCATCTTAATTGGTGGAGGTGTTTCTTCATGTCGAAAAAAATCGGA
ATCGAACAATCTCTTTCTGA

Product: YkuR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKLDELAAIRRDLHQIPELGFQEYKTQAYLLNHLAKHPEGRIEIEKWRTGLFVKVKGTAPEKILAYRADMDGLSIREDTG
YSFSSVHQDRMHACGHDFHMTIALGIIDHFVRHPVKQDLLFLFQPAEEGPGGAEPMLESDLFKKWEPSMITALHIAPELP
VGTIGTKSGLLFANTSELVIELEGKGGHAAYPHLAEDMVVAASSLVTQMQSIVARNVDPLDSAVITIGTITGGSAQNIIA
QEARLEGTIRTLSPASMEQVKKRIEAMVRGLETAYQCSGKVSYPAAYYQVCNSSDLVEDFMQFVSENGLAEVVRSKEAMT
GEDFGYMLKKYPGFMFWLGVDSPYGLHHAKLQPKEEALETAVRVMTAYFSSKAN

Sequences:

>Translated_374_residues
MKLDELAAIRRDLHQIPELGFQEYKTQAYLLNHLAKHPEGRIEIEKWRTGLFVKVKGTAPEKILAYRADMDGLSIREDTG
YSFSSVHQDRMHACGHDFHMTIALGIIDHFVRHPVKQDLLFLFQPAEEGPGGAEPMLESDLFKKWEPSMITALHIAPELP
VGTIGTKSGLLFANTSELVIELEGKGGHAAYPHLAEDMVVAASSLVTQMQSIVARNVDPLDSAVITIGTITGGSAQNIIA
QEARLEGTIRTLSPASMEQVKKRIEAMVRGLETAYQCSGKVSYPAAYYQVCNSSDLVEDFMQFVSENGLAEVVRSKEAMT
GEDFGYMLKKYPGFMFWLGVDSPYGLHHAKLQPKEEALETAVRVMTAYFSSKAN
>Mature_374_residues
MKLDELAAIRRDLHQIPELGFQEYKTQAYLLNHLAKHPEGRIEIEKWRTGLFVKVKGTAPEKILAYRADMDGLSIREDTG
YSFSSVHQDRMHACGHDFHMTIALGIIDHFVRHPVKQDLLFLFQPAEEGPGGAEPMLESDLFKKWEPSMITALHIAPELP
VGTIGTKSGLLFANTSELVIELEGKGGHAAYPHLAEDMVVAASSLVTQMQSIVARNVDPLDSAVITIGTITGGSAQNIIA
QEARLEGTIRTLSPASMEQVKKRIEAMVRGLETAYQCSGKVSYPAAYYQVCNSSDLVEDFMQFVSENGLAEVVRSKEAMT
GEDFGYMLKKYPGFMFWLGVDSPYGLHHAKLQPKEEALETAVRVMTAYFSSKAN

Specific function: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapL subfamily

Homologues:

Organism=Escherichia coli, GI87081880, Length=324, Percent_Identity=25.3086419753086, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPL_BACLD (Q65K84)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078810.1
- RefSeq:   YP_091223.1
- HSSP:   P54970
- ProteinModelPortal:   Q65K84
- STRING:   Q65K84
- EnsemblBacteria:   EBBACT00000057566
- EnsemblBacteria:   EBBACT00000059152
- GeneID:   3030746
- GeneID:   3100876
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01633
- KEGG:   bli:BL05143
- NMPDR:   fig|279010.5.peg.1304
- eggNOG:   COG1473
- GeneTree:   EBGT00070000031832
- HOGENOM:   HBG708500
- OMA:   IDYGSNY
- ProtClustDB:   CLSK2752387
- BioCyc:   BLIC279010-1:BLI01633-MONOMER
- BioCyc:   BLIC279010:BL05143-MONOMER
- HAMAP:   MF_01692
- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650
- PIRSF:   PIRSF005962
- TIGRFAMs:   TIGR01891

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.5.1.47

Molecular weight: Translated: 41409; Mature: 41409

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2; PS00178 AA_TRNA_LIGASE_I

Important sites: ACT_SITE 69-69 ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDELAAIRRDLHQIPELGFQEYKTQAYLLNHLAKHPEGRIEIEKWRTGLFVKVKGTAP
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCC
EKILAYRADMDGLSIREDTGYSFSSVHQDRMHACGHDFHMTIALGIIDHFVRHPVKQDLL
HHHHHEECCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHE
FLFQPAEEGPGGAEPMLESDLFKKWEPSMITALHIAPELPVGTIGTKSGLLFANTSELVI
EEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCEEEE
ELEGKGGHAAYPHLAEDMVVAASSLVTQMQSIVARNVDPLDSAVITIGTITGGSAQNIIA
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
QEARLEGTIRTLSPASMEQVKKRIEAMVRGLETAYQCSGKVSYPAAYYQVCNSSDLVEDF
HHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHH
MQFVSENGLAEVVRSKEAMTGEDFGYMLKKYPGFMFWLGVDSPYGLHHAKLQPKEEALET
HHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
AVRVMTAYFSSKAN
HHHHHHHHHHCCCC
>Mature Secondary Structure
MKLDELAAIRRDLHQIPELGFQEYKTQAYLLNHLAKHPEGRIEIEKWRTGLFVKVKGTAP
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCC
EKILAYRADMDGLSIREDTGYSFSSVHQDRMHACGHDFHMTIALGIIDHFVRHPVKQDLL
HHHHHEECCCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHE
FLFQPAEEGPGGAEPMLESDLFKKWEPSMITALHIAPELPVGTIGTKSGLLFANTSELVI
EEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCEEEE
ELEGKGGHAAYPHLAEDMVVAASSLVTQMQSIVARNVDPLDSAVITIGTITGGSAQNIIA
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHH
QEARLEGTIRTLSPASMEQVKKRIEAMVRGLETAYQCSGKVSYPAAYYQVCNSSDLVEDF
HHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHH
MQFVSENGLAEVVRSKEAMTGEDFGYMLKKYPGFMFWLGVDSPYGLHHAKLQPKEEALET
HHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
AVRVMTAYFSSKAN
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA