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The map label for this gene is fabF [H]

Identifier: 52784994

GI number: 52784994

Start: 1231709

End: 1232947

Strand: Direct

Name: fabF [H]

Synonym: BLi01222

Alternate gene names: 52784994

Gene position: 1231709-1232947 (Clockwise)

Preceding gene: 52784993

Following gene: 52784995

Centisome position: 29.17

GC content: 51.09

Gene sequence:

>1239_bases
ATGAATAGTAAAAGAGTAGTCATTACCGGATTAGGAGCTTTATCACCTCTTGGTAATGACGTCAAAACAAGCTGGAACAA
CGCGATCAACGGGGTTTCCGGAGTCGGCCCGATAACAAGGGTGAACGCGGACGAGTATCCTGCTAAAGTAGCCGCAGAAC
TGAAAGATTTTAAGATAGAAGATTATATGGATAAAAAAGAAGCGAGAAAAATGGACCGCTTCACACAATATGCCGTTGTG
TCGGCGAAAATGGCCGTGGAAGACGCGGGCCTCGACATTAACGAAAGCAACGCAGACCGGATCGGCGTCTGGGTCGGTTC
CGGAATCGGCGGCCTTGAAACGCTTGAACAGCAGTTCGAAACATTTTTAACAAAAGGACCGCGGCGCGTCAGCCCGTTCT
TTGTACCGATGATGATTCCTGATATGGCGACCGGCCAGATTTCGATCTCTCTCGGTGCAAAAGGGGTCAACTCTTGTACG
GTGACGGCTTGCGCGACGGGTACAAACTCAATCGGCGACGCTTTCAAGGTCATTCAGCGCGGCGATGCCGATGTCATGAT
CTCCGGAGGAACGGAAGCCCCGCTTACAAGAATGTCATTTGCCGGCTTTTCAGCCAATAAAGCGCTATCCACTAATCCGG
ATCCGAAAACGGCAAGCCGTCCGTTTGACAAAAACCGCGACGGCTTCGTCATGGGAGAAGGAGCTGGAATCGTCGTTCTT
GAGGAGCTTGAGCACGCCTTAAACCGCGGAGCGACAATCTACGCGGAAGTGGTCGGCTACGGATCAACGGGAGACGCCTA
TCATATTACGGCACCTGCGCCAAATGGAGAAGGCGGCGTCAGAGCCATGAAAGAAGCGATCAAAGATGCGGGTCTGTCCC
CTGTGGACATTGATTATATCAATGCTCATGGAACAAGCACGCCGTACAATGATAAATTTGAAACGATCGCCATTAAAGAA
GTGTTCGGAGAGCATGCCTACAAGCTTGCCGTCAGCTCGACAAAATCGATGACAGGGCACTTGCTCGGGGCTGCCGGAGG
CATCGAAGCGATTTTCTCCGTCCTTGCCATTAAGGAAGGCATCATTCCTCCGACAATCAATATCGAAACGCCTGATGAAG
ATTGCGATCTGGACTATGTACCGGATCAAGCCCGCCGCCAGGACGTGAATGTTGTGCTCAGCAACTCGCTTGGTTTCGGC
GGACACAACGCAACGCTGATCTTCAAAAAATATGAATAA

Upstream 100 bases:

>100_bases
AGACGGTGACGTCATTGTGATGGTCGGCTTCGGCGGAGGTTTGACATGGGGAGCCATCGCCATGCGCTGGGGCCGCTAAA
AGAAAGGTGAGGTGCAACTT

Downstream 100 bases:

>100_bases
CCCGCAATATAAACGGCTGCCATTTTAAATGGTGGCCGTTTTTTTTAGCGTGCATACCATACAGATGAAAAAGGAGTGTG
ATCTAAAATGAGTATAGCAA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MNSKRVVITGLGALSPLGNDVKTSWNNAINGVSGVGPITRVNADEYPAKVAAELKDFKIEDYMDKKEARKMDRFTQYAVV
SAKMAVEDAGLDINESNADRIGVWVGSGIGGLETLEQQFETFLTKGPRRVSPFFVPMMIPDMATGQISISLGAKGVNSCT
VTACATGTNSIGDAFKVIQRGDADVMISGGTEAPLTRMSFAGFSANKALSTNPDPKTASRPFDKNRDGFVMGEGAGIVVL
EELEHALNRGATIYAEVVGYGSTGDAYHITAPAPNGEGGVRAMKEAIKDAGLSPVDIDYINAHGTSTPYNDKFETIAIKE
VFGEHAYKLAVSSTKSMTGHLLGAAGGIEAIFSVLAIKEGIIPPTINIETPDEDCDLDYVPDQARRQDVNVVLSNSLGFG
GHNATLIFKKYE

Sequences:

>Translated_412_residues
MNSKRVVITGLGALSPLGNDVKTSWNNAINGVSGVGPITRVNADEYPAKVAAELKDFKIEDYMDKKEARKMDRFTQYAVV
SAKMAVEDAGLDINESNADRIGVWVGSGIGGLETLEQQFETFLTKGPRRVSPFFVPMMIPDMATGQISISLGAKGVNSCT
VTACATGTNSIGDAFKVIQRGDADVMISGGTEAPLTRMSFAGFSANKALSTNPDPKTASRPFDKNRDGFVMGEGAGIVVL
EELEHALNRGATIYAEVVGYGSTGDAYHITAPAPNGEGGVRAMKEAIKDAGLSPVDIDYINAHGTSTPYNDKFETIAIKE
VFGEHAYKLAVSSTKSMTGHLLGAAGGIEAIFSVLAIKEGIIPPTINIETPDEDCDLDYVPDQARRQDVNVVLSNSLGFG
GHNATLIFKKYE
>Mature_412_residues
MNSKRVVITGLGALSPLGNDVKTSWNNAINGVSGVGPITRVNADEYPAKVAAELKDFKIEDYMDKKEARKMDRFTQYAVV
SAKMAVEDAGLDINESNADRIGVWVGSGIGGLETLEQQFETFLTKGPRRVSPFFVPMMIPDMATGQISISLGAKGVNSCT
VTACATGTNSIGDAFKVIQRGDADVMISGGTEAPLTRMSFAGFSANKALSTNPDPKTASRPFDKNRDGFVMGEGAGIVVL
EELEHALNRGATIYAEVVGYGSTGDAYHITAPAPNGEGGVRAMKEAIKDAGLSPVDIDYINAHGTSTPYNDKFETIAIKE
VFGEHAYKLAVSSTKSMTGHLLGAAGGIEAIFSVLAIKEGIIPPTINIETPDEDCDLDYVPDQARRQDVNVVLSNSLGFG
GHNATLIFKKYE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=48.1927710843374, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI223972627, Length=170, Percent_Identity=51.1764705882353, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI41872631, Length=422, Percent_Identity=25.5924170616114, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1787337, Length=412, Percent_Identity=51.9417475728155, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1788663, Length=419, Percent_Identity=41.2887828162291, Blast_Score=262, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=38.0722891566265, Blast_Score=274, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI71983535, Length=262, Percent_Identity=45.8015267175573, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI212642053, Length=358, Percent_Identity=27.3743016759777, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=277, Percent_Identity=30.6859205776173, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320904, Length=444, Percent_Identity=38.2882882882883, Blast_Score=295, Evalue=9e-81,
Organism=Drosophila melanogaster, GI24644341, Length=422, Percent_Identity=46.6824644549763, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19920632, Length=424, Percent_Identity=26.1792452830189, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221330659, Length=423, Percent_Identity=25.7683215130024, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24581345, Length=424, Percent_Identity=25, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43757; Mature: 43757

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKRVVITGLGALSPLGNDVKTSWNNAINGVSGVGPITRVNADEYPAKVAAELKDFKIE
CCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHH
DYMDKKEARKMDRFTQYAVVSAKMAVEDAGLDINESNADRIGVWVGSGIGGLETLEQQFE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
TFLTKGPRRVSPFFVPMMIPDMATGQISISLGAKGVNSCTVTACATGTNSIGDAFKVIQR
HHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHC
GDADVMISGGTEAPLTRMSFAGFSANKALSTNPDPKTASRPFDKNRDGFVMGEGAGIVVL
CCCCEEEECCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEH
EELEHALNRGATIYAEVVGYGSTGDAYHITAPAPNGEGGVRAMKEAIKDAGLSPVDIDYI
HHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
NAHGTSTPYNDKFETIAIKEVFGEHAYKLAVSSTKSMTGHLLGAAGGIEAIFSVLAIKEG
ECCCCCCCCCCCCCEEEHHHHHCCHHEEEEECCCCHHHHHHEECCCHHHHHHHHHHHHCC
IIPPTINIETPDEDCDLDYVPDQARRQDVNVVLSNSLGFGGHNATLIFKKYE
CCCCEEEECCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MNSKRVVITGLGALSPLGNDVKTSWNNAINGVSGVGPITRVNADEYPAKVAAELKDFKIE
CCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCCHH
DYMDKKEARKMDRFTQYAVVSAKMAVEDAGLDINESNADRIGVWVGSGIGGLETLEQQFE
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
TFLTKGPRRVSPFFVPMMIPDMATGQISISLGAKGVNSCTVTACATGTNSIGDAFKVIQR
HHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHC
GDADVMISGGTEAPLTRMSFAGFSANKALSTNPDPKTASRPFDKNRDGFVMGEGAGIVVL
CCCCEEEECCCCCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEH
EELEHALNRGATIYAEVVGYGSTGDAYHITAPAPNGEGGVRAMKEAIKDAGLSPVDIDYI
HHHHHHHHCCCEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
NAHGTSTPYNDKFETIAIKEVFGEHAYKLAVSSTKSMTGHLLGAAGGIEAIFSVLAIKEG
ECCCCCCCCCCCCCEEEHHHHHCCHHEEEEECCCCHHHHHHEECCCHHHHHHHHHHHHCC
IIPPTINIETPDEDCDLDYVPDQARRQDVNVVLSNSLGFGGHNATLIFKKYE
CCCCEEEECCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]