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The map label for this gene is fabHA [H]

Identifier: 52784993

GI number: 52784993

Start: 1230749

End: 1231687

Strand: Direct

Name: fabHA [H]

Synonym: BLi01221

Alternate gene names: 52784993

Gene position: 1230749-1231687 (Clockwise)

Preceding gene: 52784991

Following gene: 52784994

Centisome position: 29.15

GC content: 49.31

Gene sequence:

>939_bases
ATGAAAGCTGGAATTATTGGAATCGGCCGGTACATCCCTGAAAAGGTGCTGACCAATTTCGACTTGGAAAAAATGGTTGA
AACTTCTGACGAGTGGATTCGTACAAGAACAGGCATAGAAGAAAGAAGAATCGCAGCCGAAGATGAGAAAACGTCCGATA
TGGCTGTGGCCGCCGCAAGAAGAGCGATGGAAGATGCAAACATCGAGCCGGAAGATCTTGATATGATTCTCGTCGCCACC
GTTACTCCTGATCAGGCATTCCCGACAGTGTCCTGCATGATTCAAGAAAAGCTCGGTGCATTCAATGCCTGTGCAATGGA
TATCAGCGCAGCGTGCGCCGGTTTTATGTACGGCTTAGTCACTGGAAAACAGTTTATCGAAGCCGGCACATATAAGCATG
TGCTTGTCATCGGAGTTGAAAAGCTTTCAGGCATTACGGACTGGGATGACCGCAATACCGCCGTTCTGTTCGGAGACGGT
GCGGGCGCCGCGGTTGTCGGCCCTGTCAGCGACGATAAAGGGATTCTGTCCTTTGAACTAGGTGCAGACGGCAGAGGCGG
AAAACACTTGTACTTGGATGAAAAAGATCATACAATCATGAATGGCAGAGAAGTGTTCAAGTTTGCCGTCCGCCAAATGG
GTGAATCCAGTGTAAATGTTATTGAAAAAGCGGGATTATCCAAAGAGGATGTCGACTTTTTGGTGCCGCACCAAGCCAAC
ATCCGGATCATGGAAGCGGCGCGCGAACGTTTGGAGCTTCCGGTCGAAAAAATGTCGAAAACGGTTCATAAATACGGAAA
CACATCAGCTGCTTCTATTCCGATTTCTCTTGTGGAAGAGCTTGAAGCTGGTAAAATAAAAGACGGTGACGTCATTGTGA
TGGTCGGCTTCGGCGGAGGTTTGACATGGGGAGCCATCGCCATGCGCTGGGGCCGCTAA

Upstream 100 bases:

>100_bases
ATATTGCCAACTAAAAAAAAATAGGGTAGGATTAGTACCAGATACTAATAATTACTCATAACATTAGTTGGAAAAAATCA
TGAATAAAGGAGTCTTTCCT

Downstream 100 bases:

>100_bases
AAGAAAGGTGAGGTGCAACTTATGAATAGTAAAAGAGTAGTCATTACCGGATTAGGAGCTTTATCACCTCTTGGTAATGA
CGTCAAAACAAGCTGGAACA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKAGIIGIGRYIPEKVLTNFDLEKMVETSDEWIRTRTGIEERRIAAEDEKTSDMAVAAARRAMEDANIEPEDLDMILVAT
VTPDQAFPTVSCMIQEKLGAFNACAMDISAACAGFMYGLVTGKQFIEAGTYKHVLVIGVEKLSGITDWDDRNTAVLFGDG
AGAAVVGPVSDDKGILSFELGADGRGGKHLYLDEKDHTIMNGREVFKFAVRQMGESSVNVIEKAGLSKEDVDFLVPHQAN
IRIMEAARERLELPVEKMSKTVHKYGNTSAASIPISLVEELEAGKIKDGDVIVMVGFGGGLTWGAIAMRWGR

Sequences:

>Translated_312_residues
MKAGIIGIGRYIPEKVLTNFDLEKMVETSDEWIRTRTGIEERRIAAEDEKTSDMAVAAARRAMEDANIEPEDLDMILVAT
VTPDQAFPTVSCMIQEKLGAFNACAMDISAACAGFMYGLVTGKQFIEAGTYKHVLVIGVEKLSGITDWDDRNTAVLFGDG
AGAAVVGPVSDDKGILSFELGADGRGGKHLYLDEKDHTIMNGREVFKFAVRQMGESSVNVIEKAGLSKEDVDFLVPHQAN
IRIMEAARERLELPVEKMSKTVHKYGNTSAASIPISLVEELEAGKIKDGDVIVMVGFGGGLTWGAIAMRWGR
>Mature_312_residues
MKAGIIGIGRYIPEKVLTNFDLEKMVETSDEWIRTRTGIEERRIAAEDEKTSDMAVAAARRAMEDANIEPEDLDMILVAT
VTPDQAFPTVSCMIQEKLGAFNACAMDISAACAGFMYGLVTGKQFIEAGTYKHVLVIGVEKLSGITDWDDRNTAVLFGDG
AGAAVVGPVSDDKGILSFELGADGRGGKHLYLDEKDHTIMNGREVFKFAVRQMGESSVNVIEKAGLSKEDVDFLVPHQAN
IRIMEAARERLELPVEKMSKTVHKYGNTSAASIPISLVEELEAGKIKDGDVIVMVGFGGGLTWGAIAMRWGR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=318, Percent_Identity=44.9685534591195, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 33877; Mature: 33877

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAGIIGIGRYIPEKVLTNFDLEKMVETSDEWIRTRTGIEERRIAAEDEKTSDMAVAAAR
CCCCEEEHHHHHHHHHHCCCCHHHHHHCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
RAMEDANIEPEDLDMILVATVTPDQAFPTVSCMIQEKLGAFNACAMDISAACAGFMYGLV
HHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TGKQFIEAGTYKHVLVIGVEKLSGITDWDDRNTAVLFGDGAGAAVVGPVSDDKGILSFEL
HHHHHHHCCCCEEEEEEEEHHHCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEEEEE
GADGRGGKHLYLDEKDHTIMNGREVFKFAVRQMGESSVNVIEKAGLSKEDVDFLVPHQAN
CCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCC
IRIMEAARERLELPVEKMSKTVHKYGNTSAASIPISLVEELEAGKIKDGDVIVMVGFGGG
EEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCC
LTWGAIAMRWGR
CHHHHHEEECCC
>Mature Secondary Structure
MKAGIIGIGRYIPEKVLTNFDLEKMVETSDEWIRTRTGIEERRIAAEDEKTSDMAVAAAR
CCCCEEEHHHHHHHHHHCCCCHHHHHHCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHH
RAMEDANIEPEDLDMILVATVTPDQAFPTVSCMIQEKLGAFNACAMDISAACAGFMYGLV
HHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TGKQFIEAGTYKHVLVIGVEKLSGITDWDDRNTAVLFGDGAGAAVVGPVSDDKGILSFEL
HHHHHHHCCCCEEEEEEEEHHHCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEEEEE
GADGRGGKHLYLDEKDHTIMNGREVFKFAVRQMGESSVNVIEKAGLSKEDVDFLVPHQAN
CCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEECCCCCC
IRIMEAARERLELPVEKMSKTVHKYGNTSAASIPISLVEELEAGKIKDGDVIVMVGFGGG
EEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCC
LTWGAIAMRWGR
CHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA