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The map label for this gene is argD [H]

Identifier: 52784981

GI number: 52784981

Start: 1219641

End: 1220798

Strand: Direct

Name: argD [H]

Synonym: BLi01209

Alternate gene names: 52784981

Gene position: 1219641-1220798 (Clockwise)

Preceding gene: 52784980

Following gene: 52784982

Centisome position: 28.88

GC content: 51.38

Gene sequence:

>1158_bases
GTGAGTCACTTATTTCAAACGTACAGCCGCTGGAATATCAATATTAAAAAAGCGAAAGGCACGATCGTCCAGGATGAGAA
GGGGAACGCCTATCTCGATTTCGTCCAGGGAATCGCGGTCTGCAATCTCGGGCATTGCCCCGATTCAGTAACGGCTGCTC
TCAAAAAACAGCTTGACGATGTCTGGCATGTTTCCAATTTGTTTCAAAATGAGCTTCAAGAAAAGGTTGCACAGCTCCTT
GCCAAAAACAGTGCAGGCGATCTCGTCTTCTTTTGCAACAGCGGGGCGGAAGCGAATGAAGGGGCGGTGAAGCTTGCGCG
AAAACATACGAAAAAAACAAAAATCGTAACCTTTCAGCAATCGTTCCACGGGCGCACGTATGCGGGAATGGCTGCAACCG
GACAGGAAAAGATCAAGCACGGATTCGGACCGATGCTTGAAGGATTCCATTACCTCCCTTACAACGAGCCGAAAGCATTT
GCCGAATTGCAGGACGAAAAAGATATCGCGGCGGTCATGCTGGAGCCGATTCAAGGCGAAGGCGGCGTCATCCCGGCGAG
CAGAGAATTTCTGCAGAGCGTTCAAGACTTTTGCCGAGATAAGCAGGCTCTCCTTATCATTGATGAAGTTCAAACCGGAA
TCGGCCGCACCGGTAAAGCATTCGGATATGAACACGAAGGGCTGTCACCCGATATCGTCACCGTTGCGAAAGGGCTGGGC
AGCGGTTTTCCGGTCGGAGCGGTCATCGGCAAAAAAGAGCTCTCAGAAGCGTTTTCGCCGGGCTCCCACGGCACGACATT
CGGAGGGAACATGCTTGCGATGGCTGCGGCAAATGCCACGTTGGAGACCATTTTTGACAGAAGCTTTCTTGAAGAAGTGA
GCGCCAAAGGAGCATTTTTGCATCAACAGCTGAAAGATAAGCTCCAATTTCCGCTTGTGAAAGATATCCGCGGGAAAGGG
CTGATCGCCGGAATCGAGTGCAAAGAACCCGTGCAGCCGCTGATCGAAGCGCTTCAAAAAGAAGGCCTGCTCGTTCTTCC
TGCGGGTCCGAACGTCATCAGGCTTCTGCCGCCGTTGACGGTTGCGAAAAGCGAAATCAAAGCGGCCGTGGAGAAGCTGA
AAGATGTCATGGCAAATCATTCTGCTGTAAAGCAGTAA

Upstream 100 bases:

>100_bases
ATGAAGTGGAAGAAGTAATGATCGTAAGCGGGAAAGGATCTTTCCTGACGAAAGACGATTTCATCGGCACGAAAATCATC
AAACAAAAGGAGGCCGTATC

Downstream 100 bases:

>100_bases
TTTTTTTTGAAATGAAAGTATAAAAATTCATGAATATCACTATTTATTCATCAAAGGTGGGCATAAGATGGAAGGATATT
TAGTTCTTGAAGATGGTACA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSHLFQTYSRWNINIKKAKGTIVQDEKGNAYLDFVQGIAVCNLGHCPDSVTAALKKQLDDVWHVSNLFQNELQEKVAQLL
AKNSAGDLVFFCNSGAEANEGAVKLARKHTKKTKIVTFQQSFHGRTYAGMAATGQEKIKHGFGPMLEGFHYLPYNEPKAF
AELQDEKDIAAVMLEPIQGEGGVIPASREFLQSVQDFCRDKQALLIIDEVQTGIGRTGKAFGYEHEGLSPDIVTVAKGLG
SGFPVGAVIGKKELSEAFSPGSHGTTFGGNMLAMAAANATLETIFDRSFLEEVSAKGAFLHQQLKDKLQFPLVKDIRGKG
LIAGIECKEPVQPLIEALQKEGLLVLPAGPNVIRLLPPLTVAKSEIKAAVEKLKDVMANHSAVKQ

Sequences:

>Translated_385_residues
MSHLFQTYSRWNINIKKAKGTIVQDEKGNAYLDFVQGIAVCNLGHCPDSVTAALKKQLDDVWHVSNLFQNELQEKVAQLL
AKNSAGDLVFFCNSGAEANEGAVKLARKHTKKTKIVTFQQSFHGRTYAGMAATGQEKIKHGFGPMLEGFHYLPYNEPKAF
AELQDEKDIAAVMLEPIQGEGGVIPASREFLQSVQDFCRDKQALLIIDEVQTGIGRTGKAFGYEHEGLSPDIVTVAKGLG
SGFPVGAVIGKKELSEAFSPGSHGTTFGGNMLAMAAANATLETIFDRSFLEEVSAKGAFLHQQLKDKLQFPLVKDIRGKG
LIAGIECKEPVQPLIEALQKEGLLVLPAGPNVIRLLPPLTVAKSEIKAAVEKLKDVMANHSAVKQ
>Mature_384_residues
SHLFQTYSRWNINIKKAKGTIVQDEKGNAYLDFVQGIAVCNLGHCPDSVTAALKKQLDDVWHVSNLFQNELQEKVAQLLA
KNSAGDLVFFCNSGAEANEGAVKLARKHTKKTKIVTFQQSFHGRTYAGMAATGQEKIKHGFGPMLEGFHYLPYNEPKAFA
ELQDEKDIAAVMLEPIQGEGGVIPASREFLQSVQDFCRDKQALLIIDEVQTGIGRTGKAFGYEHEGLSPDIVTVAKGLGS
GFPVGAVIGKKELSEAFSPGSHGTTFGGNMLAMAAANATLETIFDRSFLEEVSAKGAFLHQQLKDKLQFPLVKDIRGKGL
IAGIECKEPVQPLIEALQKEGLLVLPAGPNVIRLLPPLTVAKSEIKAAVEKLKDVMANHSAVKQ

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=33.7730870712401, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI284507298, Length=292, Percent_Identity=36.3013698630137, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI13994255, Length=415, Percent_Identity=32.5301204819277, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=29.2383292383292, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI24119277, Length=409, Percent_Identity=27.3838630806846, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226442705, Length=407, Percent_Identity=28.5012285012285, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI226442709, Length=377, Percent_Identity=28.9124668435013, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI188536080, Length=434, Percent_Identity=21.889400921659, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38679950, Length=434, Percent_Identity=21.889400921659, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38679946, Length=434, Percent_Identity=21.889400921659, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1789759, Length=373, Percent_Identity=41.8230563002681, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI1788044, Length=368, Percent_Identity=39.6739130434783, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=35.5, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI145693181, Length=373, Percent_Identity=35.3887399463807, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789016, Length=391, Percent_Identity=32.9923273657289, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786991, Length=372, Percent_Identity=31.4516129032258, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786349, Length=284, Percent_Identity=30.9859154929577, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=377, Percent_Identity=33.9522546419098, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI32564660, Length=420, Percent_Identity=31.6666666666667, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71992977, Length=423, Percent_Identity=31.4420803782506, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI25144274, Length=260, Percent_Identity=36.5384615384615, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17541228, Length=450, Percent_Identity=23.5555555555556, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=29.4478527607362, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71992985, Length=116, Percent_Identity=32.7586206896552, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=38.5012919896641, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=398, Percent_Identity=33.4170854271357, Blast_Score=209, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=355, Percent_Identity=28.169014084507, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=26.8691588785047, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21357415, Length=383, Percent_Identity=31.0704960835509, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI161085790, Length=413, Percent_Identity=29.2978208232446, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI28574759, Length=404, Percent_Identity=29.9504950495049, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21356575, Length=399, Percent_Identity=28.8220551378446, Blast_Score=151, Evalue=9e-37,
Organism=Drosophila melanogaster, GI281366494, Length=297, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667139, Length=297, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667143, Length=297, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41753; Mature: 41621

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLFQTYSRWNINIKKAKGTIVQDEKGNAYLDFVQGIAVCNLGHCPDSVTAALKKQLDD
CCHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VWHVSNLFQNELQEKVAQLLAKNSAGDLVFFCNSGAEANEGAVKLARKHTKKTKIVTFQQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEH
SFHGRTYAGMAATGQEKIKHGFGPMLEGFHYLPYNEPKAFAELQDEKDIAAVMLEPIQGE
HHCCCEEECCCCCCHHHHHHCCCHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCC
GGVIPASREFLQSVQDFCRDKQALLIIDEVQTGIGRTGKAFGYEHEGLSPDIVTVAKGLG
CCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCC
SGFPVGAVIGKKELSEAFSPGSHGTTFGGNMLAMAAANATLETIFDRSFLEEVSAKGAFL
CCCCHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HQQLKDKLQFPLVKDIRGKGLIAGIECKEPVQPLIEALQKEGLLVLPAGPNVIRLLPPLT
HHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCEEEEECCCCEEEECCCHH
VAKSEIKAAVEKLKDVMANHSAVKQ
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SHLFQTYSRWNINIKKAKGTIVQDEKGNAYLDFVQGIAVCNLGHCPDSVTAALKKQLDD
CHHHHHHHHCCEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VWHVSNLFQNELQEKVAQLLAKNSAGDLVFFCNSGAEANEGAVKLARKHTKKTKIVTFQQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEH
SFHGRTYAGMAATGQEKIKHGFGPMLEGFHYLPYNEPKAFAELQDEKDIAAVMLEPIQGE
HHCCCEEECCCCCCHHHHHHCCCHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCC
GGVIPASREFLQSVQDFCRDKQALLIIDEVQTGIGRTGKAFGYEHEGLSPDIVTVAKGLG
CCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCC
SGFPVGAVIGKKELSEAFSPGSHGTTFGGNMLAMAAANATLETIFDRSFLEEVSAKGAFL
CCCCHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HQQLKDKLQFPLVKDIRGKGLIAGIECKEPVQPLIEALQKEGLLVLPAGPNVIRLLPPLT
HHHHHHHHCCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCEEEEECCCCEEEECCCHH
VAKSEIKAAVEKLKDVMANHSAVKQ
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025667; 9384377 [H]