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The map label for this gene is argB

Identifier: 52784980

GI number: 52784980

Start: 1218868

End: 1219644

Strand: Direct

Name: argB

Synonym: BLi01208

Alternate gene names: 52784980

Gene position: 1218868-1219644 (Clockwise)

Preceding gene: 52784979

Following gene: 52784981

Centisome position: 28.87

GC content: 48.39

Gene sequence:

>777_bases
ATGGGTAAAACAATCGTTTTTAAATGCGGCGGAAGCGTCATCCGCGAACTCTCGGACGAATTTTTTCAAAACCTGAAAGA
TCTGACTGAAAGCGGCTGGAAAATCGCGCTCGTGCACGGGGGTGGACCCGATATTACAAAGATGCTGAAGAAGCTCAATA
TTCGAACCGAATTCGTCAACGGACAGCGCAAGACGACAAAAGCGGTTCTTGAAGTCGCTGAAATGGTCCTGTCCGGTTCG
ATCAACAAATTTTTCGTTGCTGAGCTGACAAAGCACGGGCTTCCGGCTGTCGGCGTATCGGGAAAAGACGGGGGACTGCT
CCTTGCAGACTATTTAAATGAAAAGGAATACGGTCAAGTCGGGCGCATTAAAAAAGTAAACGGCCAAATGGCCGAAGCGC
TCATGGAAAAAGGATTTATTCCGGTTATCGCACCCCTCTCGATGACGGATGGCTGTGAGACCTTGAATGTGAACGCCGAT
TTGGCGGCGTCGGCTGTTGCGGCAGCCTTGCGCGCTGACAAATTGATGTTTGTGACAGATGTCAAAGGAATTATGAAAAA
CGAAGAAATGCTGAAAGAGCTGACGCCCGAAGACATCGAAAGCCTGATTGCTGAAGGCGTGATCTCGGGAGGCATGATAC
CAAAAGTGCATTCCGCAAAAGAGGCTCTTACAGATGAAGTGGAAGAAGTAATGATCGTAAGCGGGAAAGGATCTTTCCTG
ACGAAAGACGATTTCATCGGCACGAAAATCATCAAACAAAAGGAGGCCGTATCGTGA

Upstream 100 bases:

>100_bases
TGCAGGAAGGTGAAGGAAAGGGTACGGCTTGGGGCTGCGATTTAACTTATGAATACGTCAAAATCAATGCGAGCTATCGT
ACGTAAAAAAGGGGATCACA

Downstream 100 bases:

>100_bases
GTCACTTATTTCAAACGTACAGCCGCTGGAATATCAATATTAAAAAAGCGAAAGGCACGATCGTCCAGGATGAGAAGGGG
AACGCCTATCTCGATTTCGT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MGKTIVFKCGGSVIRELSDEFFQNLKDLTESGWKIALVHGGGPDITKMLKKLNIRTEFVNGQRKTTKAVLEVAEMVLSGS
INKFFVAELTKHGLPAVGVSGKDGGLLLADYLNEKEYGQVGRIKKVNGQMAEALMEKGFIPVIAPLSMTDGCETLNVNAD
LAASAVAAALRADKLMFVTDVKGIMKNEEMLKELTPEDIESLIAEGVISGGMIPKVHSAKEALTDEVEEVMIVSGKGSFL
TKDDFIGTKIIKQKEAVS

Sequences:

>Translated_258_residues
MGKTIVFKCGGSVIRELSDEFFQNLKDLTESGWKIALVHGGGPDITKMLKKLNIRTEFVNGQRKTTKAVLEVAEMVLSGS
INKFFVAELTKHGLPAVGVSGKDGGLLLADYLNEKEYGQVGRIKKVNGQMAEALMEKGFIPVIAPLSMTDGCETLNVNAD
LAASAVAAALRADKLMFVTDVKGIMKNEEMLKELTPEDIESLIAEGVISGGMIPKVHSAKEALTDEVEEVMIVSGKGSFL
TKDDFIGTKIIKQKEAVS
>Mature_257_residues
GKTIVFKCGGSVIRELSDEFFQNLKDLTESGWKIALVHGGGPDITKMLKKLNIRTEFVNGQRKTTKAVLEVAEMVLSGSI
NKFFVAELTKHGLPAVGVSGKDGGLLLADYLNEKEYGQVGRIKKVNGQMAEALMEKGFIPVIAPLSMTDGCETLNVNADL
AASAVAAALRADKLMFVTDVKGIMKNEEMLKELTPEDIESLIAEGVISGGMIPKVHSAKEALTDEVEEVMIVSGKGSFLT
KDDFIGTKIIKQKEAVS

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=226, Percent_Identity=34.5132743362832, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320913, Length=269, Percent_Identity=26.0223048327138, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_BACLD (Q65LE8)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078408.1
- RefSeq:   YP_090809.1
- ProteinModelPortal:   Q65LE8
- SMR:   Q65LE8
- STRING:   Q65LE8
- EnsemblBacteria:   EBBACT00000054630
- EnsemblBacteria:   EBBACT00000060957
- GeneID:   3030197
- GeneID:   3101134
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01208
- KEGG:   bli:BL03243
- NMPDR:   fig|279010.5.peg.2377
- eggNOG:   COG0548
- GeneTree:   EBGT00050000001971
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   BLIC279010-1:BLI01208-MONOMER
- BioCyc:   BLIC279010:BL03243-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27778; Mature: 27647

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: BINDING 63-63 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTIVFKCGGSVIRELSDEFFQNLKDLTESGWKIALVHGGGPDITKMLKKLNIRTEFVN
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHHCC
GQRKTTKAVLEVAEMVLSGSINKFFVAELTKHGLPAVGVSGKDGGLLLADYLNEKEYGQV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCCCCCEEHHHHCCCHHCCCC
GRIKKVNGQMAEALMEKGFIPVIAPLSMTDGCETLNVNADLAASAVAAALRADKLMFVTD
CCEEHHCHHHHHHHHHCCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHCCEEEEHH
VKGIMKNEEMLKELTPEDIESLIAEGVISGGMIPKVHSAKEALTDEVEEVMIVSGKGSFL
HHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCC
TKDDFIGTKIIKQKEAVS
CCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKTIVFKCGGSVIRELSDEFFQNLKDLTESGWKIALVHGGGPDITKMLKKLNIRTEFVN
CCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHHCC
GQRKTTKAVLEVAEMVLSGSINKFFVAELTKHGLPAVGVSGKDGGLLLADYLNEKEYGQV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCCCCCEEHHHHCCCHHCCCC
GRIKKVNGQMAEALMEKGFIPVIAPLSMTDGCETLNVNADLAASAVAAALRADKLMFVTD
CCEEHHCHHHHHHHHHCCCCEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHCCEEEEHH
VKGIMKNEEMLKELTPEDIESLIAEGVISGGMIPKVHSAKEALTDEVEEVMIVSGKGSFL
HHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCC
TKDDFIGTKIIKQKEAVS
CCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA