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The map label for this gene is yhfN [H]

Identifier: 52784880

GI number: 52784880

Start: 1107652

End: 1108908

Strand: Direct

Name: yhfN [H]

Synonym: BLi01108

Alternate gene names: 52784880

Gene position: 1107652-1108908 (Clockwise)

Preceding gene: 52784879

Following gene: 52784882

Centisome position: 26.23

GC content: 46.46

Gene sequence:

>1257_bases
ATGCGGAAATGGATCGCGGGAGCCTTTCTCCTGTATGTGCTGTACGGCCTTTTTTTCTATTGGTATCTCTTTATGGCCGG
TGAACCCTCCGTTCCCGAGGCGCTGAAAGGGACAAGCGCAGACCCGGCGACATTTATGAACGAAAGGGAACTCATGCTGA
CGGAAGAGTACTCGAAAATAAAGGACTTTCTGTTTTTTATCCGGATTCCGTTTGAGTGGTTCTTATTTTTAATATTGTTG
ATTGCCGGTTTATCGAAGAAAATGAAGAATTGGGCGGAGCAGACGTCAAAGCGGAGAACGATTCAAATAACGGCATATGT
TTTTGCTTTGTTTCTGATCGTCACGATCGTTTCTTTGCCGCTTGACTGGATCAGCTATCAATATTCGCTTGACTACGGCA
TATCAACACAGACAACCGCGAGCTGGATCAAAGACCAGGTGATCGACTTCTGGATCAGCTTTCCGATAACGGCTGCGGCG
GTGATCGTCTTTTACTTTTTGATCAAAAAGCATGAAAAACGCTGGTGGTTTTATGCCTGGTGCCTGACGGTTCCGGTTAC
GCTGTTTTTATTTTTCCTTCAGCCGGTTGTCATCGATCCTTTATACAATGACTTTTATCCGCTGAAAAATAAAGATCTCG
AACAAAGCATTCTGAAGCTGGCCGATCAGGCAGATATTCCTGCGAATCACGTCTATGAAGTGAACATGTCTGAAAAAACG
AATGCGTTAAATGCTTATGTGACAGGGATCGGCGCCAATAAAAGGATTGTGCTCTGGGATACCACGCTGAACAAGCTGGA
TGAGCCGGAAATTTTATTCATTATGGCGCACGAAATGGGGCACTATGTGATGAAGCATGTTTACATAGGACTCGGCGGGT
ACCTGCTTTTATCCCTTGCCGTCTTTTATGTGATCGACAAGCTGTACAAGCGGATCATCGGCCGCTATGGAAAAAGCCTC
CGCATTGCGGGAAAATCCGATCTTGCCGCACTCCCGCTTCTCCTGATGCTGATGGGGGTCATCTCTTTCGCGTCTTCTCC
ATTTACAAACGCAGTTTCGAGGCATCAGGAAAAAGCCGCTGACCAGTATGCGATTGAACTGACGAACAACAGCGATGCAG
CGGTTGCGACTTTTCAAGAGCTCTCAAAAGCCGGGTTGAGCGAGGCGAACCCGCCGTTTCTCGTCAAGATTTTTAAATAC
GGCCATCCGACCATAATGGAACGGATTCAAAATATTGAACAGTCTTCAACTGAATGA

Upstream 100 bases:

>100_bases
CAGGGGCCGGCCTCTTGCTCTCATTGTAAGGCTTGGTTCTAACTTTCACAGGAAAAGCTTACAATAGAAGTAACTGCTAT
GTGAGAGGAAGTGATTCGCC

Downstream 100 bases:

>100_bases
AGAAAAAGCTAGTGCTAAAAACACTAGCTTTTTCTATATGCCATTTGTTAGAATATGTTATTGAGCGGCAGCTTCGACAT
TGATCAGACCTTTTCCATAG

Product: YhfN

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MRKWIAGAFLLYVLYGLFFYWYLFMAGEPSVPEALKGTSADPATFMNERELMLTEEYSKIKDFLFFIRIPFEWFLFLILL
IAGLSKKMKNWAEQTSKRRTIQITAYVFALFLIVTIVSLPLDWISYQYSLDYGISTQTTASWIKDQVIDFWISFPITAAA
VIVFYFLIKKHEKRWWFYAWCLTVPVTLFLFFLQPVVIDPLYNDFYPLKNKDLEQSILKLADQADIPANHVYEVNMSEKT
NALNAYVTGIGANKRIVLWDTTLNKLDEPEILFIMAHEMGHYVMKHVYIGLGGYLLLSLAVFYVIDKLYKRIIGRYGKSL
RIAGKSDLAALPLLLMLMGVISFASSPFTNAVSRHQEKAADQYAIELTNNSDAAVATFQELSKAGLSEANPPFLVKIFKY
GHPTIMERIQNIEQSSTE

Sequences:

>Translated_418_residues
MRKWIAGAFLLYVLYGLFFYWYLFMAGEPSVPEALKGTSADPATFMNERELMLTEEYSKIKDFLFFIRIPFEWFLFLILL
IAGLSKKMKNWAEQTSKRRTIQITAYVFALFLIVTIVSLPLDWISYQYSLDYGISTQTTASWIKDQVIDFWISFPITAAA
VIVFYFLIKKHEKRWWFYAWCLTVPVTLFLFFLQPVVIDPLYNDFYPLKNKDLEQSILKLADQADIPANHVYEVNMSEKT
NALNAYVTGIGANKRIVLWDTTLNKLDEPEILFIMAHEMGHYVMKHVYIGLGGYLLLSLAVFYVIDKLYKRIIGRYGKSL
RIAGKSDLAALPLLLMLMGVISFASSPFTNAVSRHQEKAADQYAIELTNNSDAAVATFQELSKAGLSEANPPFLVKIFKY
GHPTIMERIQNIEQSSTE
>Mature_418_residues
MRKWIAGAFLLYVLYGLFFYWYLFMAGEPSVPEALKGTSADPATFMNERELMLTEEYSKIKDFLFFIRIPFEWFLFLILL
IAGLSKKMKNWAEQTSKRRTIQITAYVFALFLIVTIVSLPLDWISYQYSLDYGISTQTTASWIKDQVIDFWISFPITAAA
VIVFYFLIKKHEKRWWFYAWCLTVPVTLFLFFLQPVVIDPLYNDFYPLKNKDLEQSILKLADQADIPANHVYEVNMSEKT
NALNAYVTGIGANKRIVLWDTTLNKLDEPEILFIMAHEMGHYVMKHVYIGLGGYLLLSLAVFYVIDKLYKRIIGRYGKSL
RIAGKSDLAALPLLLMLMGVISFASSPFTNAVSRHQEKAADQYAIELTNNSDAAVATFQELSKAGLSEANPPFLVKIFKY
GHPTIMERIQNIEQSSTE

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=389, Percent_Identity=25.9640102827763, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17505484, Length=415, Percent_Identity=24.8192771084337, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6322577, Length=301, Percent_Identity=26.2458471760797, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922414, Length=415, Percent_Identity=24.0963855421687, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 48097; Mature: 48097

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00142 ZINC_PROTEASE ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKWIAGAFLLYVLYGLFFYWYLFMAGEPSVPEALKGTSADPATFMNERELMLTEEYSKI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHCCCHHHHHHHHHHH
KDFLFFIRIPFEWFLFLILLIAGLSKKMKNWAEQTSKRRTIQITAYVFALFLIVTIVSLP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCC
LDWISYQYSLDYGISTQTTASWIKDQVIDFWISFPITAAAVIVFYFLIKKHEKRWWFYAW
HHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
CLTVPVTLFLFFLQPVVIDPLYNDFYPLKNKDLEQSILKLADQADIPANHVYEVNMSEKT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCC
NALNAYVTGIGANKRIVLWDTTLNKLDEPEILFIMAHEMGHYVMKHVYIGLGGYLLLSLA
CHHHHEEEEECCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VFYVIDKLYKRIIGRYGKSLRIAGKSDLAALPLLLMLMGVISFASSPFTNAVSRHQEKAA
HHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
DQYAIELTNNSDAAVATFQELSKAGLSEANPPFLVKIFKYGHPTIMERIQNIEQSSTE
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKWIAGAFLLYVLYGLFFYWYLFMAGEPSVPEALKGTSADPATFMNERELMLTEEYSKI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHCCCHHHHHHHHHHH
KDFLFFIRIPFEWFLFLILLIAGLSKKMKNWAEQTSKRRTIQITAYVFALFLIVTIVSLP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCC
LDWISYQYSLDYGISTQTTASWIKDQVIDFWISFPITAAAVIVFYFLIKKHEKRWWFYAW
HHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
CLTVPVTLFLFFLQPVVIDPLYNDFYPLKNKDLEQSILKLADQADIPANHVYEVNMSEKT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCC
NALNAYVTGIGANKRIVLWDTTLNKLDEPEILFIMAHEMGHYVMKHVYIGLGGYLLLSLA
CHHHHEEEEECCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VFYVIDKLYKRIIGRYGKSLRIAGKSDLAALPLLLMLMGVISFASSPFTNAVSRHQEKAA
HHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
DQYAIELTNNSDAAVATFQELSKAGLSEANPPFLVKIFKYGHPTIMERIQNIEQSSTE
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]