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The map label for this gene is citR [H]

Identifier: 52784781

GI number: 52784781

Start: 1011610

End: 1012488

Strand: Reverse

Name: citR [H]

Synonym: BLi01009

Alternate gene names: 52784781

Gene position: 1012488-1011610 (Counterclockwise)

Preceding gene: 52784787

Following gene: 52784777

Centisome position: 23.98

GC content: 47.33

Gene sequence:

>879_bases
ATGGATTTTAAATGGCTTCATACCTTTGTCACTGCCGCAAAATACGAAAATTTCAGAAAGACGGCGGAAACCTTATTTAT
TTCTCAGCCGACCGTCACCGTCCAAATTAAACTGCTTGAAGAAGAACTCGGGTGCCAGCTGTTCACCCGCAAAGGAAGAA
GCATTCATTTAACGAAAGAAGGACGGGCTTACCTTCCTTTTGCCCTTCGCCTGTTGGAAGACTATGAATCGAGCATGGCA
GAGCTTCACAGAATCAGACAAGGCTACTCACAGACATTGAACTTAGCGGTTTCGCCGCTTATCGCCGATACGATTCTCCC
ATTTGTATTAAAAAAATACACAGCGCTGCATCCGAATTCGGAGATCAAAGTAAAGATCGCCGAATCAGCTGAAATCGCTC
CCCTGATTTCAGCTGGCCATGCAGATATCGGACTAAGCTGCTTAAACGTGCAATCGTCAAACCTGAACTGCTATTCCATG
TACAGCGATCCCGTGATTTTGGTTGCCCCTCATGACGGCCGCGCTGCAGAACAAGCGCCGCCGCTCGATGTCGAGGATTT
GCTTGAAGAATATTTGCTGTTGACCCACAATCACCCTGAATACTGGGACGACCTCGTCAGGCAGCTGAGGATCAAGTTTC
CGTTTGTCAGAACGATGCTCGTAAGCCAGACGCATATTACGAAACGATTTATTTCAGAAGGACTCGGTATATCATTTTTG
CCGCTGTCGACTGTGCGCCGCGAGCTGATGGAAGGAAGATTAATAGAGGTGCCGTGCGATTTCATGAAGCTTCCCGTTGC
AGGGGGATATGCGATTAGTCTGAAAGATAATGAGAAGGTCGAGCACTTTTTGGCGTTTTTAGCCGAGTTCCGTTTCTAA

Upstream 100 bases:

>100_bases
CCTTTTTCCTTTGTAAATATTATTATAGTTGATATAATATTTAAAAAATATTGAATTATATTGATGTCTTTGATTAATAA
AATTAATCAGGAGGACTGCA

Downstream 100 bases:

>100_bases
ACGGAAAAAACCCGTTCATCATGATGAACGGGCTTGTCCCTGCAACATTAGAAGCGTTTTGCTCCAAGATAGCGGGGCTT
CCAATAGCTGTTTGTCATAT

Product: CitR

Products: NA

Alternate protein names: Citrate synthase I repressor [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDFKWLHTFVTAAKYENFRKTAETLFISQPTVTVQIKLLEEELGCQLFTRKGRSIHLTKEGRAYLPFALRLLEDYESSMA
ELHRIRQGYSQTLNLAVSPLIADTILPFVLKKYTALHPNSEIKVKIAESAEIAPLISAGHADIGLSCLNVQSSNLNCYSM
YSDPVILVAPHDGRAAEQAPPLDVEDLLEEYLLLTHNHPEYWDDLVRQLRIKFPFVRTMLVSQTHITKRFISEGLGISFL
PLSTVRRELMEGRLIEVPCDFMKLPVAGGYAISLKDNEKVEHFLAFLAEFRF

Sequences:

>Translated_292_residues
MDFKWLHTFVTAAKYENFRKTAETLFISQPTVTVQIKLLEEELGCQLFTRKGRSIHLTKEGRAYLPFALRLLEDYESSMA
ELHRIRQGYSQTLNLAVSPLIADTILPFVLKKYTALHPNSEIKVKIAESAEIAPLISAGHADIGLSCLNVQSSNLNCYSM
YSDPVILVAPHDGRAAEQAPPLDVEDLLEEYLLLTHNHPEYWDDLVRQLRIKFPFVRTMLVSQTHITKRFISEGLGISFL
PLSTVRRELMEGRLIEVPCDFMKLPVAGGYAISLKDNEKVEHFLAFLAEFRF
>Mature_292_residues
MDFKWLHTFVTAAKYENFRKTAETLFISQPTVTVQIKLLEEELGCQLFTRKGRSIHLTKEGRAYLPFALRLLEDYESSMA
ELHRIRQGYSQTLNLAVSPLIADTILPFVLKKYTALHPNSEIKVKIAESAEIAPLISAGHADIGLSCLNVQSSNLNCYSM
YSDPVILVAPHDGRAAEQAPPLDVEDLLEEYLLLTHNHPEYWDDLVRQLRIKFPFVRTMLVSQTHITKRFISEGLGISFL
PLSTVRRELMEGRLIEVPCDFMKLPVAGGYAISLKDNEKVEHFLAFLAEFRF

Specific function: Negative regulatory protein for the citA gene for citrate synthase I [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=169, Percent_Identity=30.1775147928994, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787879, Length=266, Percent_Identity=27.8195488721804, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788296, Length=250, Percent_Identity=28, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790783, Length=305, Percent_Identity=23.6065573770492, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788887, Length=172, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI157672245, Length=165, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790208, Length=171, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081904, Length=144, Percent_Identity=28.4722222222222, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082132, Length=267, Percent_Identity=24.3445692883895, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367136, Length=240, Percent_Identity=24.5833333333333, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790399, Length=268, Percent_Identity=23.134328358209, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788626, Length=166, Percent_Identity=27.1084337349398, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=265, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=125, Percent_Identity=29.6, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786713, Length=271, Percent_Identity=26.5682656826568, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787530, Length=167, Percent_Identity=28.7425149700599, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788481, Length=265, Percent_Identity=23.7735849056604, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787589, Length=262, Percent_Identity=24.4274809160305, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33255; Mature: 33255

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKWLHTFVTAAKYENFRKTAETLFISQPTVTVQIKLLEEELGCQLFTRKGRSIHLTKE
CCHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEHHHHCCHHEECCCCEEEEECC
GRAYLPFALRLLEDYESSMAELHRIRQGYSQTLNLAVSPLIADTILPFVLKKYTALHPNS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EIKVKIAESAEIAPLISAGHADIGLSCLNVQSSNLNCYSMYSDPVILVAPHDGRAAEQAP
CEEEEEECCCCCCHHHCCCCCCCCEEEEEEECCCCEEEEEECCCEEEEECCCCCCCCCCC
PLDVEDLLEEYLLLTHNHPEYWDDLVRQLRIKFPFVRTMLVSQTHITKRFISEGLGISFL
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
PLSTVRRELMEGRLIEVPCDFMKLPVAGGYAISLKDNEKVEHFLAFLAEFRF
CHHHHHHHHHCCCEEECCCCCEECCCCCCEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFKWLHTFVTAAKYENFRKTAETLFISQPTVTVQIKLLEEELGCQLFTRKGRSIHLTKE
CCHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEHHHHCCHHEECCCCEEEEECC
GRAYLPFALRLLEDYESSMAELHRIRQGYSQTLNLAVSPLIADTILPFVLKKYTALHPNS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EIKVKIAESAEIAPLISAGHADIGLSCLNVQSSNLNCYSMYSDPVILVAPHDGRAAEQAP
CEEEEEECCCCCCHHHCCCCCCCCEEEEEEECCCCEEEEEECCCEEEEECCCCCCCCCCC
PLDVEDLLEEYLLLTHNHPEYWDDLVRQLRIKFPFVRTMLVSQTHITKRFISEGLGISFL
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
PLSTVRRELMEGRLIEVPCDFMKLPVAGGYAISLKDNEKVEHFLAFLAEFRF
CHHHHHHHHHCCCEEECCCCCEECCCCCCEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045898; 9579061; 9384377; 8045899 [H]