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The map label for this gene is purQ [H]

Identifier: 52784499

GI number: 52784499

Start: 701036

End: 701719

Strand: Direct

Name: purQ [H]

Synonym: BLi00698

Alternate gene names: 52784499

Gene position: 701036-701719 (Clockwise)

Preceding gene: 52784498

Following gene: 52784500

Centisome position: 16.6

GC content: 48.25

Gene sequence:

>684_bases
GTGAAATTTGCGGTGATTGTGCTGCCTGGCTCAAACTGCGATATCGATATGTTCCACGCGATTAAGGATGAGCTTGGCGA
AGAAGCTGAATACGTCTGGCATACAGAAACAAGTCTTGATGAATATGACGGCGTCCTCATTCCGGGAGGATTCTCATACG
GTGATTATTTAAGATGCGGCGCGATCGCCCGCTTCGCAAATATTATGCCGGCCGTCAAAAAAGCGGCTGAAGAAGGGAAG
CCGGTGCTCGGCGTCTGCAACGGATTTCAAATTTTGCAGGAGCTCGGTCTTTTGCCGGGCGCAATGAGACGCAACAAAGA
TTTGAAATTTATCTGCCGTCCGGTTGAACTGATCGTCCAAAACAATGAAACGCTTTTTACATCTTCCTACGGCAAAGGCG
AATCCATCACGATTCCGGTCGCTCACGGCGAAGGAAACTTCTACTGTGATGAAGAAACGCTTGCCGGATTACAAGAAAAC
AATCAAATCGCTTTCACATACGGAACGGATATCAACGGAAGCGTCGCCGATATTGCAGGCGTCGTCAATGAAAAAGGCAA
TGTATTAGGCATGATGCCTCACCCAGAACGCGCAGTCGATTCTCTGCTCGGAAGCGCCGACGGTCTTAAACTGTTTCAAT
CTATCGTGAAAAATTGGAGGGAAACTCATGTCGCTACTGCTTGA

Upstream 100 bases:

>100_bases
ACCGCGACCTTGACGTTCTCGTCAAAGAAATGTGCGAAAAACTTTTGGCCAACACGGTGATTGAAGATTACAGATACGAA
GTCGAGGAGGTTGTCGCACA

Downstream 100 bases:

>100_bases
ACCAAGTCAAGAACAAATTAAGGAAGAGAAACTTTATCAGCAAATGGGTGTCAGCGATGACGAGTTTGCCATGATTGAAT
CGATTCTCGGAAGGCTTCCA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKFAVIVLPGSNCDIDMFHAIKDELGEEAEYVWHTETSLDEYDGVLIPGGFSYGDYLRCGAIARFANIMPAVKKAAEEGK
PVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQNNETLFTSSYGKGESITIPVAHGEGNFYCDEETLAGLQEN
NQIAFTYGTDINGSVADIAGVVNEKGNVLGMMPHPERAVDSLLGSADGLKLFQSIVKNWRETHVATA

Sequences:

>Translated_227_residues
MKFAVIVLPGSNCDIDMFHAIKDELGEEAEYVWHTETSLDEYDGVLIPGGFSYGDYLRCGAIARFANIMPAVKKAAEEGK
PVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQNNETLFTSSYGKGESITIPVAHGEGNFYCDEETLAGLQEN
NQIAFTYGTDINGSVADIAGVVNEKGNVLGMMPHPERAVDSLLGSADGLKLFQSIVKNWRETHVATA
>Mature_227_residues
MKFAVIVLPGSNCDIDMFHAIKDELGEEAEYVWHTETSLDEYDGVLIPGGFSYGDYLRCGAIARFANIMPAVKKAAEEGK
PVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQNNETLFTSSYGKGESITIPVAHGEGNFYCDEETLAGLQEN
NQIAFTYGTDINGSVADIAGVVNEKGNVLGMMPHPERAVDSLLGSADGLKLFQSIVKNWRETHVATA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=232, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=191, Percent_Identity=29.8429319371728, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24582111, Length=190, Percent_Identity=32.1052631578947, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582109, Length=190, Percent_Identity=32.1052631578947, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17137292, Length=190, Percent_Identity=32.1052631578947, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24704; Mature: 24704

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIVLPGSNCDIDMFHAIKDELGEEAEYVWHTETSLDEYDGVLIPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHCCCEEECCCCCCCHHHHHH
AIARFANIMPAVKKAAEEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQ
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCHHHCCCCHHEEEEEEHEEEE
NNETLFTSSYGKGESITIPVAHGEGNFYCDEETLAGLQENNQIAFTYGTDINGSVADIAG
CCCEEEEECCCCCCEEEEEEEECCCCEEECHHHHCCCCCCCEEEEEECCCCCCCHHHHHH
VVNEKGNVLGMMPHPERAVDSLLGSADGLKLFQSIVKNWRETHVATA
HHCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFAVIVLPGSNCDIDMFHAIKDELGEEAEYVWHTETSLDEYDGVLIPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHCCCEEECCCCCCCHHHHHH
AIARFANIMPAVKKAAEEGKPVLGVCNGFQILQELGLLPGAMRRNKDLKFICRPVELIVQ
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCHHHCCCCHHEEEEEEHEEEE
NNETLFTSSYGKGESITIPVAHGEGNFYCDEETLAGLQENNQIAFTYGTDINGSVADIAG
CCCEEEEECCCCCCEEEEEEEECCCCEEECHHHHCCCCCCCEEEEEECCCCCCCHHHHHH
VVNEKGNVLGMMPHPERAVDSLLGSADGLKLFQSIVKNWRETHVATA
HHCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA