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The map label for this gene is rsbU [H]

Identifier: 52784377

GI number: 52784377

Start: 561553

End: 562560

Strand: Direct

Name: rsbU [H]

Synonym: BLi00557

Alternate gene names: 52784377

Gene position: 561553-562560 (Clockwise)

Preceding gene: 52784376

Following gene: 52784378

Centisome position: 13.3

GC content: 41.96

Gene sequence:

>1008_bases
ATGGATTTCAGGGAAGTGATTGAGCAGCGCTATCGACAGCTGCTTAGCCGTTATATATCTGAATTAACAGAGACATCCCT
TTATCAGGGGCAGAAATTCAGCAGAAAAACGATTGAACATCAAGTGCCGCCGGAAGAGATTATCAGCATACACCGAAAAG
TTCTGTCTGAATTATATCCGGATCTTCCAGACCATGTGTTCCATTCTCTCGATTTTTTAATTGAAGTGATGATTGGATAC
GGTTTGGCCTATCAAGAACATCAAACATTAAGAGGAATTCAGCAGGAAATTAAATCGGAAATTGAAATTGCCGCGAATGT
CCAGCAAACGCTGCTTGAGACGACGGTTCCGAAAGTTGAAGCGCTCGAAATCGGTGCGGTCAGCATTCCGGCCAAGCAAA
TGAGCGGTGATTATTATCATTTTGTGCGCGACAAGGAATCGATTAATATCGCCATTGCGGATGTAATCGGGAAAGGAATA
CCGGCTGCGTTATGCATGTCGATGATCAAATATGCGATGGACTCTCTGCCGGATTCGGGCACGTCTCCTTCACAGGTGCT
GAAAAACCTGAACAGGGTCGTCGAACAAAATGTAGACCCAAGCATGTTTATTACAATGTTTTATGGCAACTATCATCTTC
AAAAACACCTATTTACGTTTTCATCTGCCGGTCATGAACCTGGCTTTTATTATTCTTGCAGGGAAAATAAATTTTACGAT
TTAAACGCAAAAGGCCTCGTTCTTGGCATTTCATCAAATTACGACTATGAGCAGTACGAGCAAAAACTGGATATTGGCGA
TATGATCGTTCTTTTTTCAGATGGTGTAACTGAATGCCGGACAGACAGCGGGTTTTTGGAGCGGTCTGACTTGCAGAACC
TGATTACTGTACATATGGAGAAACCGGCTCAGCAAATGGTTGACAATATATACGAACATCTGCTCAAGCTTCAGGATTTT
CAGCTTCATGATGATTTTACTCTCATTGTTTTAAAAAGAAAGGTTTAA

Upstream 100 bases:

>100_bases
CCGGGAGTAAAGCGTCTGATGGACCAATTTGAATTGCATTCGGACGCGGAAAATGGAACGGATATACAAGCCGTAAAATG
GCTGCGGTAGGAGGGAAGGA

Downstream 100 bases:

>100_bases
AGCTTCTCTTCGCTGGGTAATAAACCAGTAGCTCATTAAGAGAACCAGAGGTGATATTGTGAATTTGGCAGTTGATACGA
ATAAAAATGACCATGTGATA

Product: hypothetical protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDFREVIEQRYRQLLSRYISELTETSLYQGQKFSRKTIEHQVPPEEIISIHRKVLSELYPDLPDHVFHSLDFLIEVMIGY
GLAYQEHQTLRGIQQEIKSEIEIAANVQQTLLETTVPKVEALEIGAVSIPAKQMSGDYYHFVRDKESINIAIADVIGKGI
PAALCMSMIKYAMDSLPDSGTSPSQVLKNLNRVVEQNVDPSMFITMFYGNYHLQKHLFTFSSAGHEPGFYYSCRENKFYD
LNAKGLVLGISSNYDYEQYEQKLDIGDMIVLFSDGVTECRTDSGFLERSDLQNLITVHMEKPAQQMVDNIYEHLLKLQDF
QLHDDFTLIVLKRKV

Sequences:

>Translated_335_residues
MDFREVIEQRYRQLLSRYISELTETSLYQGQKFSRKTIEHQVPPEEIISIHRKVLSELYPDLPDHVFHSLDFLIEVMIGY
GLAYQEHQTLRGIQQEIKSEIEIAANVQQTLLETTVPKVEALEIGAVSIPAKQMSGDYYHFVRDKESINIAIADVIGKGI
PAALCMSMIKYAMDSLPDSGTSPSQVLKNLNRVVEQNVDPSMFITMFYGNYHLQKHLFTFSSAGHEPGFYYSCRENKFYD
LNAKGLVLGISSNYDYEQYEQKLDIGDMIVLFSDGVTECRTDSGFLERSDLQNLITVHMEKPAQQMVDNIYEHLLKLQDF
QLHDDFTLIVLKRKV
>Mature_335_residues
MDFREVIEQRYRQLLSRYISELTETSLYQGQKFSRKTIEHQVPPEEIISIHRKVLSELYPDLPDHVFHSLDFLIEVMIGY
GLAYQEHQTLRGIQQEIKSEIEIAANVQQTLLETTVPKVEALEIGAVSIPAKQMSGDYYHFVRDKESINIAIADVIGKGI
PAALCMSMIKYAMDSLPDSGTSPSQVLKNLNRVVEQNVDPSMFITMFYGNYHLQKHLFTFSSAGHEPGFYYSCRENKFYD
LNAKGLVLGISSNYDYEQYEQKLDIGDMIVLFSDGVTECRTDSGFLERSDLQNLITVHMEKPAQQMVDNIYEHLLKLQDF
QLHDDFTLIVLKRKV

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 38554; Mature: 38554

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFREVIEQRYRQLLSRYISELTETSLYQGQKFSRKTIEHQVPPEEIISIHRKVLSELYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
DLPDHVFHSLDFLIEVMIGYGLAYQEHQTLRGIQQEIKSEIEIAANVQQTLLETTVPKVE
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALEIGAVSIPAKQMSGDYYHFVRDKESINIAIADVIGKGIPAALCMSMIKYAMDSLPDSG
HEECCCEECCHHHHCCCEEEEECCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHCCCCC
TSPSQVLKNLNRVVEQNVDPSMFITMFYGNYHLQKHLFTFSSAGHEPGFYYSCRENKFYD
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCEEEE
LNAKGLVLGISSNYDYEQYEQKLDIGDMIVLFSDGVTECRTDSGFLERSDLQNLITVHME
ECCCEEEEEECCCCCHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHC
KPAQQMVDNIYEHLLKLQDFQLHDDFTLIVLKRKV
CHHHHHHHHHHHHHHHHHCCEECCCEEEEEEEECC
>Mature Secondary Structure
MDFREVIEQRYRQLLSRYISELTETSLYQGQKFSRKTIEHQVPPEEIISIHRKVLSELYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
DLPDHVFHSLDFLIEVMIGYGLAYQEHQTLRGIQQEIKSEIEIAANVQQTLLETTVPKVE
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALEIGAVSIPAKQMSGDYYHFVRDKESINIAIADVIGKGIPAALCMSMIKYAMDSLPDSG
HEECCCEECCHHHHCCCEEEEECCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHCCCCC
TSPSQVLKNLNRVVEQNVDPSMFITMFYGNYHLQKHLFTFSSAGHEPGFYYSCRENKFYD
CCHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCEEEE
LNAKGLVLGISSNYDYEQYEQKLDIGDMIVLFSDGVTECRTDSGFLERSDLQNLITVHME
ECCCEEEEEECCCCCHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCHHHHHHHHHHHHC
KPAQQMVDNIYEHLLKLQDFQLHDDFTLIVLKRKV
CHHHHHHHHHHHHHHHHHCCEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]