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The map label for this gene is kipR [H]

Identifier: 52784323

GI number: 52784323

Start: 509146

End: 509916

Strand: Direct

Name: kipR [H]

Synonym: BLi00503

Alternate gene names: 52784323

Gene position: 509146-509916 (Clockwise)

Preceding gene: 52784322

Following gene: 52784324

Centisome position: 12.06

GC content: 51.36

Gene sequence:

>771_bases
GTGTATCAGGAGGGGGAAGGCATGGAACATAAAAACAAAACAGTCGTCAAAGCCATGACCCTGCTCAATCTGTTCCTGAC
GAGAGAAAGGCTCTCGCTGGGCGACATGATTGAGCTGACAGGCATGCCGAAAACATCTGTCTACCGCATGGTTTGTTCTC
TCGAAGAAATGGGTTTTCTCGACCGCGACGAGAACGGGATGTATAGCTTAGGACTGCTGTTTTTGCAATACGGCCACCTT
GTTTCAGAAAGGCTTGATATTCGAAAAATCGCTCTGCCCATCATGGAAGAACTCCGCGATGACGTGGATGAAGCCGTCCA
TTTAATTGTAAGGCAGGGAAATGAAGCAATGTATATAGAAAAAATTGAGGGCACGCAGACCGTTCGCCTCTATACAGCGA
TCGGGAGGCGGTCCCCTTTATATGCCGGAGCCTGTGCGAGAAGCATTCTGACGTTTTTGCCTGAAGAGGAGCGGGATGCC
TATATCGAGCAAACAGAGCTGGTGCCGATCGCTTCCGGCACGATCCGGGACAAGGCTGAGCTGATCCGCATTGTGGACGA
GTCGTACCGGAGCGGCTGCACGGTCAGTCATTCGGAGCTCGAAGACTACACCTCCGCGATTGCCGCGCCGATTTTCAATC
ATAAGCGCGAAGTCGCAGCTGGGATCAGCATCGCCGGGTTTGAAGCCCGCTTTCAGAAAGACCGTCTTCCTTATTTGACC
GAAAGAGTGAAAAAGGCGGCGCTTGACATCTCGAGAAAATTAGGTTTTTAG

Upstream 100 bases:

>100_bases
AGCCTTCAGGAAGCAGAGCGCGTTTACATCGAACGGGAGACGAAAATCAGCGAACTTTCTGCCCGATTGAAGCTTGAATA
CATGTTATGATAGGTGTGAT

Downstream 100 bases:

>100_bases
GAAAAAAGAAAAGTATCCTTTCGAGCCTCTGCCGAGTACATATATGGTAGCTGCCGCGAAAAAACGGCATATCGGAGGGG
GAAAGGATATGACGCTTCAA

Product: KipR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MYQEGEGMEHKNKTVVKAMTLLNLFLTRERLSLGDMIELTGMPKTSVYRMVCSLEEMGFLDRDENGMYSLGLLFLQYGHL
VSERLDIRKIALPIMEELRDDVDEAVHLIVRQGNEAMYIEKIEGTQTVRLYTAIGRRSPLYAGACARSILTFLPEEERDA
YIEQTELVPIASGTIRDKAELIRIVDESYRSGCTVSHSELEDYTSAIAAPIFNHKREVAAGISIAGFEARFQKDRLPYLT
ERVKKAALDISRKLGF

Sequences:

>Translated_256_residues
MYQEGEGMEHKNKTVVKAMTLLNLFLTRERLSLGDMIELTGMPKTSVYRMVCSLEEMGFLDRDENGMYSLGLLFLQYGHL
VSERLDIRKIALPIMEELRDDVDEAVHLIVRQGNEAMYIEKIEGTQTVRLYTAIGRRSPLYAGACARSILTFLPEEERDA
YIEQTELVPIASGTIRDKAELIRIVDESYRSGCTVSHSELEDYTSAIAAPIFNHKREVAAGISIAGFEARFQKDRLPYLT
ERVKKAALDISRKLGF
>Mature_256_residues
MYQEGEGMEHKNKTVVKAMTLLNLFLTRERLSLGDMIELTGMPKTSVYRMVCSLEEMGFLDRDENGMYSLGLLFLQYGHL
VSERLDIRKIALPIMEELRDDVDEAVHLIVRQGNEAMYIEKIEGTQTVRLYTAIGRRSPLYAGACARSILTFLPEEERDA
YIEQTELVPIASGTIRDKAELIRIVDESYRSGCTVSHSELEDYTSAIAAPIFNHKREVAAGISIAGFEARFQKDRLPYLT
ERVKKAALDISRKLGF

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=246, Percent_Identity=29.6747967479675, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786715, Length=216, Percent_Identity=30.5555555555556, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788131, Length=244, Percent_Identity=27.0491803278689, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788581, Length=249, Percent_Identity=27.3092369477912, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790752, Length=215, Percent_Identity=26.046511627907, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082359, Length=228, Percent_Identity=23.6842105263158, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789999, Length=228, Percent_Identity=27.6315789473684, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29050; Mature: 29050

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQEGEGMEHKNKTVVKAMTLLNLFLTRERLSLGDMIELTGMPKTSVYRMVCSLEEMGFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCC
DRDENGMYSLGLLFLQYGHLVSERLDIRKIALPIMEELRDDVDEAVHLIVRQGNEAMYIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
KIEGTQTVRLYTAIGRRSPLYAGACARSILTFLPEEERDAYIEQTELVPIASGTIRDKAE
ECCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCEEEECCCCHHHHHH
LIRIVDESYRSGCTVSHSELEDYTSAIAAPIFNHKREVAAGISIAGFEARFQKDRLPYLT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHCCCHHHH
ERVKKAALDISRKLGF
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYQEGEGMEHKNKTVVKAMTLLNLFLTRERLSLGDMIELTGMPKTSVYRMVCSLEEMGFL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCC
DRDENGMYSLGLLFLQYGHLVSERLDIRKIALPIMEELRDDVDEAVHLIVRQGNEAMYIE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
KIEGTQTVRLYTAIGRRSPLYAGACARSILTFLPEEERDAYIEQTELVPIASGTIRDKAE
ECCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCEEEECCCCHHHHHH
LIRIVDESYRSGCTVSHSELEDYTSAIAAPIFNHKREVAAGISIAGFEARFQKDRLPYLT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHCCCHHHH
ERVKKAALDISRKLGF
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]