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The map label for this gene is yclC [H]

Identifier: 52784247

GI number: 52784247

Start: 426604

End: 428025

Strand: Direct

Name: yclC [H]

Synonym: BLi00427

Alternate gene names: 52784247

Gene position: 426604-428025 (Clockwise)

Preceding gene: 52784246

Following gene: 52784248

Centisome position: 10.1

GC content: 50.7

Gene sequence:

>1422_bases
ATGGCTTATCAAGATTTTAGAGATTTTTTAAATACGCTGAAAAAAGAAGGACAGCTTCTTGAAGTCCAGGAAGAGGTGAA
GCCGGAACCCGATTTGGGAGCAGCTGCACGCGCCGCCAACAACCTCGGAGACAAATCACCCGCTCTTTTATTCAACAACA
TTTACGGCTATAACAATGCCCAAATCGCGCTGAATGTAATCGGCTCCTGGCCGAACCACGCATTAATGCTCGGCCTTCCA
AAAGACACGCCGGTTAAAGAACAATTCTTTGAGTTCGCGCGCCGTTATAATCAGTTTCCAGTAAAAGTGCAAAGAGAGGA
GACAGCGCCGTTTCACGAAAACGAAATCACAGAAGACATCAACCTGTTTGACATTCTGCCGCTCTTCCGCATCAATCAGG
GCGACGGCGGCTTTTATTTAGACAAGGCATGCGTCATTTCGAGAGATGTCGAGGATCCGGACCACTTCGGCAAGCAAAAC
GTCGGCATGTACAGATTGCAGGTAAAAGGCAAAGACCGCCTCGGCATTCAGCCCGTCCCGCAGCATGACATTGCGATCCA
CCTGCGTCAGGCTGAAGAGCGCGGCGAAAACCTGCCTGTCACGATTGCGCTCGGCTGCGAACCGGTTATTGCAACGGCGG
CATCCACACCGCTCTTATACGATCAATCAGAATACGAGATGGCAGGGGCCCTGCAAGGCGAACCATATAAAATCGTCAAA
TCAAAACTGTCTAACTTAGATATCCCATGGGGCGCAGAAGTGGTTCTCGAAGGTGAGATCCTTGCGGGCGAACGCGAGTA
TGAAGGTCCGTTCGGCGAGTTTACCGGCCACTATTCAGGCGGACGAAGCATGCCGATCATCAAAATCAAGCGCGTCTGCC
ACCGCAACAATCCGATTTTTGAACACCTGTATTTAGGCATGCCTTGGACTGAGGTTGACTATATGGTCGGCATTAATACA
TGTGTGCCGCTTTACCAGCAGCTTAAAGAGGCGTATCCGAATGAAATTGTCGCGGTAAACGCGATGTATACGCACGGCTT
GATCGCCATTGTATCAACGAAAAGCCGCTACGGCGGATTCGCCAAAGCCGTCGGCATGCGCGCGCTGACAACTCCGCACG
GCCTCGGCTACTGCAAAATGGTGATCCTCGTTGACGAAGACGTCGATCCGTTTAACCTCCCGCAAGTGATGTGGGCAATC
TCAACGAAAATGCATCCGAAACACGATGCAGTCATCATCCCGGATTTATCCGTTTTGGCGCTAGATCCAGGTTCTGAACC
GGCGGGAATCACCCACAAAATGATATTGGACGCGACAACGCCGGCTGCACCGGAAACAAGGGGACACTATTCACAGCCGC
TCGATTCCCCTATAGGAACGAAAGAGTGGGAAGCAAAATTAATGAATCTGCTAAATCAATAA

Upstream 100 bases:

>100_bases
GATCATATCGTATTTCGGACGCTGGACCAATTTGGCATCCATCTGTCTGAAGCGAAGCGCTGGGAAGGTATGAAACAGGA
GAAATAAGGAGGATAACAGA

Downstream 100 bases:

>100_bases
AAGAGGAGAGTGTTTCATCATGCATACATGTCCGCGCTGCGACTTAAAAAAAGCGGAAACCGTCAGCAAATCACCCGTTG
AAGGAGCCTGGGAAGTCTAT

Product: YclC

Products: NA

Alternate protein names: PAD; 4-hydroxybenzoate decarboxylase subunit C; 4-hydroxybenzoate DC; Phenylacrylic acid decarboxylase subunit C; Vanillate decarboxylase subunit C [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MAYQDFRDFLNTLKKEGQLLEVQEEVKPEPDLGAAARAANNLGDKSPALLFNNIYGYNNAQIALNVIGSWPNHALMLGLP
KDTPVKEQFFEFARRYNQFPVKVQREETAPFHENEITEDINLFDILPLFRINQGDGGFYLDKACVISRDVEDPDHFGKQN
VGMYRLQVKGKDRLGIQPVPQHDIAIHLRQAEERGENLPVTIALGCEPVIATAASTPLLYDQSEYEMAGALQGEPYKIVK
SKLSNLDIPWGAEVVLEGEILAGEREYEGPFGEFTGHYSGGRSMPIIKIKRVCHRNNPIFEHLYLGMPWTEVDYMVGINT
CVPLYQQLKEAYPNEIVAVNAMYTHGLIAIVSTKSRYGGFAKAVGMRALTTPHGLGYCKMVILVDEDVDPFNLPQVMWAI
STKMHPKHDAVIIPDLSVLALDPGSEPAGITHKMILDATTPAAPETRGHYSQPLDSPIGTKEWEAKLMNLLNQ

Sequences:

>Translated_473_residues
MAYQDFRDFLNTLKKEGQLLEVQEEVKPEPDLGAAARAANNLGDKSPALLFNNIYGYNNAQIALNVIGSWPNHALMLGLP
KDTPVKEQFFEFARRYNQFPVKVQREETAPFHENEITEDINLFDILPLFRINQGDGGFYLDKACVISRDVEDPDHFGKQN
VGMYRLQVKGKDRLGIQPVPQHDIAIHLRQAEERGENLPVTIALGCEPVIATAASTPLLYDQSEYEMAGALQGEPYKIVK
SKLSNLDIPWGAEVVLEGEILAGEREYEGPFGEFTGHYSGGRSMPIIKIKRVCHRNNPIFEHLYLGMPWTEVDYMVGINT
CVPLYQQLKEAYPNEIVAVNAMYTHGLIAIVSTKSRYGGFAKAVGMRALTTPHGLGYCKMVILVDEDVDPFNLPQVMWAI
STKMHPKHDAVIIPDLSVLALDPGSEPAGITHKMILDATTPAAPETRGHYSQPLDSPIGTKEWEAKLMNLLNQ
>Mature_472_residues
AYQDFRDFLNTLKKEGQLLEVQEEVKPEPDLGAAARAANNLGDKSPALLFNNIYGYNNAQIALNVIGSWPNHALMLGLPK
DTPVKEQFFEFARRYNQFPVKVQREETAPFHENEITEDINLFDILPLFRINQGDGGFYLDKACVISRDVEDPDHFGKQNV
GMYRLQVKGKDRLGIQPVPQHDIAIHLRQAEERGENLPVTIALGCEPVIATAASTPLLYDQSEYEMAGALQGEPYKIVKS
KLSNLDIPWGAEVVLEGEILAGEREYEGPFGEFTGHYSGGRSMPIIKIKRVCHRNNPIFEHLYLGMPWTEVDYMVGINTC
VPLYQQLKEAYPNEIVAVNAMYTHGLIAIVSTKSRYGGFAKAVGMRALTTPHGLGYCKMVILVDEDVDPFNLPQVMWAIS
TKMHPKHDAVIIPDLSVLALDPGSEPAGITHKMILDATTPAAPETRGHYSQPLDSPIGTKEWEAKLMNLLNQ

Specific function: Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate, vanillate and salicylate. Is not

COG id: COG0043

COG function: function code H; 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiD family [H]

Homologues:

Organism=Escherichia coli, GI1790277, Length=478, Percent_Identity=29.7071129707113, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6320748, Length=449, Percent_Identity=26.2806236080178, Blast_Score=120, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002830
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01977 UbiD [H]

EC number: =4.1.1.61 [H]

Molecular weight: Translated: 52770; Mature: 52639

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQDFRDFLNTLKKEGQLLEVQEEVKPEPDLGAAARAANNLGDKSPALLFNNIYGYNNA
CCHHHHHHHHHHHHHCCCEEEEHHHCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCC
QIALNVIGSWPNHALMLGLPKDTPVKEQFFEFARRYNQFPVKVQREETAPFHENEITEDI
EEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
NLFDILPLFRINQGDGGFYLDKACVISRDVEDPDHFGKQNVGMYRLQVKGKDRLGIQPVP
CHHEECEEEEEECCCCCEEECCEEEEECCCCCCHHCCCCCCCEEEEEECCCCCCCCCCCC
QHDIAIHLRQAEERGENLPVTIALGCEPVIATAASTPLLYDQSEYEMAGALQGEPYKIVK
CCCEEEEEEEHHHCCCCCCEEEEECCCHHHHHCCCCCEEECCCCHHHHCCCCCCCHHHHH
SKLSNLDIPWGAEVVLEGEILAGEREYEGPFGEFTGHYSGGRSMPIIKIKRVCHRNNPIF
HHHHCCCCCCCCEEEEECEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
EHLYLGMPWTEVDYMVGINTCVPLYQQLKEAYPNEIVAVNAMYTHGLIAIVSTKSRYGGF
HHEEECCCHHHHHHEEEHHHHHHHHHHHHHHCCCCEEEEEEEHHCCEEEEEECCHHHCCH
AKAVGMRALTTPHGLGYCKMVILVDEDVDPFNLPQVMWAISTKMHPKHDAVIIPDLSVLA
HHHHCCCEECCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCEEEE
LDPGSEPAGITHKMILDATTPAAPETRGHYSQPLDSPIGTKEWEAKLMNLLNQ
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AYQDFRDFLNTLKKEGQLLEVQEEVKPEPDLGAAARAANNLGDKSPALLFNNIYGYNNA
CHHHHHHHHHHHHHCCCEEEEHHHCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCC
QIALNVIGSWPNHALMLGLPKDTPVKEQFFEFARRYNQFPVKVQREETAPFHENEITEDI
EEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
NLFDILPLFRINQGDGGFYLDKACVISRDVEDPDHFGKQNVGMYRLQVKGKDRLGIQPVP
CHHEECEEEEEECCCCCEEECCEEEEECCCCCCHHCCCCCCCEEEEEECCCCCCCCCCCC
QHDIAIHLRQAEERGENLPVTIALGCEPVIATAASTPLLYDQSEYEMAGALQGEPYKIVK
CCCEEEEEEEHHHCCCCCCEEEEECCCHHHHHCCCCCEEECCCCHHHHCCCCCCCHHHHH
SKLSNLDIPWGAEVVLEGEILAGEREYEGPFGEFTGHYSGGRSMPIIKIKRVCHRNNPIF
HHHHCCCCCCCCEEEEECEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
EHLYLGMPWTEVDYMVGINTCVPLYQQLKEAYPNEIVAVNAMYTHGLIAIVSTKSRYGGF
HHEEECCCHHHHHHEEEHHHHHHHHHHHHHHCCCCEEEEEEEHHCCEEEEEECCHHHCCH
AKAVGMRALTTPHGLGYCKMVILVDEDVDPFNLPQVMWAISTKMHPKHDAVIIPDLSVLA
HHHHCCCEECCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCEEEE
LDPGSEPAGITHKMILDATTPAAPETRGHYSQPLDSPIGTKEWEAKLMNLLNQ
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]