Click here to switch to the map view.

The map label for this gene is ycgO [H]

Identifier: 52784197

GI number: 52784197

Start: 352682

End: 354106

Strand: Direct

Name: ycgO [H]

Synonym: BLi00375

Alternate gene names: 52784197

Gene position: 352682-354106 (Clockwise)

Preceding gene: 52784196

Following gene: 52784198

Centisome position: 8.35

GC content: 49.05

Gene sequence:

>1425_bases
ATGGTAGGGATGCTTTATATTGGGTATTACGCTTACAAACGGACAGCAAACCTCTCAGACTATATGCTTGGCGGACGAAC
GCTCGGGCCTGCTGTCACGGCGCTCAGCGCCGGCGCATCAGACATGAGCGGCTGGCTTTTGATGGGGCTGCCGGGCGCCA
TGTTTGCAACAGGCCTGAGCGGTTCGTGGATTGTCATCGGACTCGTACTCGGCGCTTGGGCGAACTGGATATTTGTAGCG
CCGCGTCTAAGGTCATACACCGAAGTAGCGGGCAATTCAATCACTATCCCTGCATTTTTAGAAAACCGTTTTCATGACAA
ATCAAAGATCCTGCGAATATTTTCCGGAGTCGTCATTATTACCTTTTTTACGTTTTATGTATCATCTGGAATGGTTTCCG
GGGGCGTTTTATTTAACAGCATATTTAATTTGGATTACCATGCAGGGCTGTGGATCATTTCAGGCGTTGTCGTGGCCTAC
ACGCTTTTCGGCGGGTTTTTGGCAGTCAGCTGGACGGACTTTGTCCAAGGCATCATTATGTTTGTCGCGTTAATTCTTGT
TCCGATTGTGACGGTCATTCAGACGGGAGGACCTGGAGAAGCCTTCAGCGAGATCCAGTCGATCGATCCAAACCTCCTCA
ATATTTTTAAAGGTACGAGCGTCCTCGGCATCATCTCCTTGTTCTCATGGGGCCTCGGCTATTTTGGACAGCCTCATATT
ATCGTGCGCTTTATGGCGATATCCTCCATCAAGGAAACGAAGAAAGCGCGCCGGATCGGCATGGGTTGGATGATCTTTTC
AAGTGCGGGCGCACTGCTGACCGGATTGCTCGGTATTGCGTATTACTCGAAGAACGGGCTTCACTTGGATGATCCGGAGA
CCATCTTCATTCAATTGGGTAACATCCTGTTTCACCCTCTAATCACAGGATTTTTAATCTCGGCGATTTTGGCAGCGGTT
ATGAGTACAATTTCCTCCCAGCTGCTTGTGACATCAAGTTCTCTAACTGAAGATTTATACAAAACACTATTTAAGCGCTC
TGCATCTGATAAAGAACTCGTCTTTTTCGGACGGCTTTCGGTTTTGGCGGTTTCCATTGTCGGACTCTGTCTCGCCTGGA
CAAAAAACAATACGATTCTCGGTCTTGTCAGCTATGCTTGGGCGGGTTTCGGAGCGTCGTTCGGCCCCGTGGTCATCTTA
AGTTTGTTTTGGAAGAGGATGACAAAATGGGGGGCGCTTGCCGGAATGGTTGCCGGAGCGCTTACCGTCATCATTTGGGC
GGAAGCCGGGCTTTCCGATGTTCTTTATGAAATGATTCCGGGCTTTGCCGCCAGCTTGCTGTTTGTGTTTGTCGTCAGTC
TATTGACGTCAAAACCGGAGCAGCAGGTGCTTGATGAATTCGAGCAATACAAACAAACGCTGTAA

Upstream 100 bases:

>100_bases
TTCAAAAAAAGAGAAATTAGTCTAAAAATTTAGATAAACGGCATCTTGGGGGGAGATTCTTATTCAGAACGTACAATTGA
TCATTTCCATCGTGATTTAC

Downstream 100 bases:

>100_bases
CGATGACGGAGATGGGGAACCATTCTCCGTCTCTCTTTTTATAGGCCTTCTCCCCCTTCTAACAGGGGATTGATCCCATT
TTTTTAAAAGTCGCATATAA

Product: YcgO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MVGMLYIGYYAYKRTANLSDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFATGLSGSWIVIGLVLGAWANWIFVA
PRLRSYTEVAGNSITIPAFLENRFHDKSKILRIFSGVVIITFFTFYVSSGMVSGGVLFNSIFNLDYHAGLWIISGVVVAY
TLFGGFLAVSWTDFVQGIIMFVALILVPIVTVIQTGGPGEAFSEIQSIDPNLLNIFKGTSVLGIISLFSWGLGYFGQPHI
IVRFMAISSIKETKKARRIGMGWMIFSSAGALLTGLLGIAYYSKNGLHLDDPETIFIQLGNILFHPLITGFLISAILAAV
MSTISSQLLVTSSSLTEDLYKTLFKRSASDKELVFFGRLSVLAVSIVGLCLAWTKNNTILGLVSYAWAGFGASFGPVVIL
SLFWKRMTKWGALAGMVAGALTVIIWAEAGLSDVLYEMIPGFAASLLFVFVVSLLTSKPEQQVLDEFEQYKQTL

Sequences:

>Translated_474_residues
MVGMLYIGYYAYKRTANLSDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFATGLSGSWIVIGLVLGAWANWIFVA
PRLRSYTEVAGNSITIPAFLENRFHDKSKILRIFSGVVIITFFTFYVSSGMVSGGVLFNSIFNLDYHAGLWIISGVVVAY
TLFGGFLAVSWTDFVQGIIMFVALILVPIVTVIQTGGPGEAFSEIQSIDPNLLNIFKGTSVLGIISLFSWGLGYFGQPHI
IVRFMAISSIKETKKARRIGMGWMIFSSAGALLTGLLGIAYYSKNGLHLDDPETIFIQLGNILFHPLITGFLISAILAAV
MSTISSQLLVTSSSLTEDLYKTLFKRSASDKELVFFGRLSVLAVSIVGLCLAWTKNNTILGLVSYAWAGFGASFGPVVIL
SLFWKRMTKWGALAGMVAGALTVIIWAEAGLSDVLYEMIPGFAASLLFVFVVSLLTSKPEQQVLDEFEQYKQTL
>Mature_474_residues
MVGMLYIGYYAYKRTANLSDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFATGLSGSWIVIGLVLGAWANWIFVA
PRLRSYTEVAGNSITIPAFLENRFHDKSKILRIFSGVVIITFFTFYVSSGMVSGGVLFNSIFNLDYHAGLWIISGVVVAY
TLFGGFLAVSWTDFVQGIIMFVALILVPIVTVIQTGGPGEAFSEIQSIDPNLLNIFKGTSVLGIISLFSWGLGYFGQPHI
IVRFMAISSIKETKKARRIGMGWMIFSSAGALLTGLLGIAYYSKNGLHLDDPETIFIQLGNILFHPLITGFLISAILAAV
MSTISSQLLVTSSSLTEDLYKTLFKRSASDKELVFFGRLSVLAVSIVGLCLAWTKNNTILGLVSYAWAGFGASFGPVVIL
SLFWKRMTKWGALAGMVAGALTVIIWAEAGLSDVLYEMIPGFAASLLFVFVVSLLTSKPEQQVLDEFEQYKQTL

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=480, Percent_Identity=55.8333333333333, Blast_Score=529, Evalue=1e-150,
Organism=Homo sapiens, GI110835708, Length=531, Percent_Identity=22.5988700564972, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1787251, Length=471, Percent_Identity=53.7154989384289, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1790503, Length=434, Percent_Identity=24.8847926267281, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082237, Length=425, Percent_Identity=27.2941176470588, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1790113, Length=446, Percent_Identity=22.8699551569507, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533094, Length=421, Percent_Identity=23.0403800475059, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17539284, Length=435, Percent_Identity=24.1379310344828, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24645928, Length=375, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24640370, Length=362, Percent_Identity=25.9668508287293, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221459584, Length=383, Percent_Identity=22.4543080939948, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24651739, Length=476, Percent_Identity=22.4789915966387, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221459588, Length=395, Percent_Identity=23.5443037974684, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651741, Length=359, Percent_Identity=26.7409470752089, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362918, Length=293, Percent_Identity=26.2798634812287, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221459586, Length=390, Percent_Identity=21.5384615384615, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 51354; Mature: 51354

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGMLYIGYYAYKRTANLSDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFATGLS
CCEEEEEHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHCCCC
GSWIVIGLVLGAWANWIFVAPRLRSYTEVAGNSITIPAFLENRFHDKSKILRIFSGVVII
CCHHHHHHHHHHHHHHHEECHHHHHHHHHCCCCEEEHHHHHHHHCHHHHHHHHHHHHHHH
TFFTFYVSSGMVSGGVLFNSIFNLDYHAGLWIISGVVVAYTLFGGFLAVSWTDFVQGIIM
HHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVALILVPIVTVIQTGGPGEAFSEIQSIDPNLLNIFKGTSVLGIISLFSWGLGYFGQPHI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCHH
IVRFMAISSIKETKKARRIGMGWMIFSSAGALLTGLLGIAYYSKNGLHLDDPETIFIQLG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHH
NILFHPLITGFLISAILAAVMSTISSQLLVTSSSLTEDLYKTLFKRSASDKELVFFGRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEHHHHH
VLAVSIVGLCLAWTKNNTILGLVSYAWAGFGASFGPVVILSLFWKRMTKWGALAGMVAGA
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTVIIWAEAGLSDVLYEMIPGFAASLLFVFVVSLLTSKPEQQVLDEFEQYKQTL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVGMLYIGYYAYKRTANLSDYMLGGRTLGPAVTALSAGASDMSGWLLMGLPGAMFATGLS
CCEEEEEHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHCCCC
GSWIVIGLVLGAWANWIFVAPRLRSYTEVAGNSITIPAFLENRFHDKSKILRIFSGVVII
CCHHHHHHHHHHHHHHHEECHHHHHHHHHCCCCEEEHHHHHHHHCHHHHHHHHHHHHHHH
TFFTFYVSSGMVSGGVLFNSIFNLDYHAGLWIISGVVVAYTLFGGFLAVSWTDFVQGIIM
HHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVALILVPIVTVIQTGGPGEAFSEIQSIDPNLLNIFKGTSVLGIISLFSWGLGYFGQPHI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCHH
IVRFMAISSIKETKKARRIGMGWMIFSSAGALLTGLLGIAYYSKNGLHLDDPETIFIQLG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHH
NILFHPLITGFLISAILAAVMSTISSQLLVTSSSLTEDLYKTLFKRSASDKELVFFGRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEHHHHH
VLAVSIVGLCLAWTKNNTILGLVSYAWAGFGASFGPVVILSLFWKRMTKWGALAGMVAGA
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTVIIWAEAGLSDVLYEMIPGFAASLLFVFVVSLLTSKPEQQVLDEFEQYKQTL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]