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The map label for this gene is endo I [H]

Identifier: 52784161

GI number: 52784161

Start: 314491

End: 316572

Strand: Direct

Name: endo I [H]

Synonym: BLi00339

Alternate gene names: 52784161

Gene position: 314491-316572 (Clockwise)

Preceding gene: 52784160

Following gene: 52784163

Centisome position: 7.45

GC content: 46.97

Gene sequence:

>2082_bases
ATGAAGAAAGCCGCTTCATCTTTTTTATCTTGTATGCTGCTCCTCGCGCTTTTTATCCCGAACCGGCAGATTTCCGCAGA
GACTTCAAGCGAAAGACCGGACTGCCGTCCGGAAGGGCTATGGGACTCGGGCGTTGAACATGTGCCGTATTGCGATGTAT
ACGACAAGGACGGCCGTGAAAAGCTGGCCAATCAGTTAGACCGGAGAATCATCGGTTACTTTACGAGCTGGCGTACGGGA
AAAGGAAATCAAGATCGTTATTTAGTAAGCGATATCCCCTGGAAGTACTTGAGCCACATTAATTATGCGTTTGCCCACAT
CGGGGAAGATCATCGGATTTCAGTCGGAGAAGAGGCAGATGAGAACAACCCGTCCATCGGGATGACTTGGCCGGAGCATC
CCGATGTAAAAATGGATCAAACCTTGCCGTATAAGGGGCATTTTAACCTTATCCATCAATATAAAGATAGATACCCGGAT
GTGAAGGTTTTGGCCGCTGTCGGCGGTTGGGCCGAAACCGGCGGCTATGTCGACAAGGACGGAAAGCGAATTCCAAGCGG
CGGCTTTTACTCGATGACAACGAATGGAGATGGATCTGTAAACCACAAGGGTATTCACACCTTTGCGGAATCGGTCGTTG
CGTTTCTCAGAAAATATGAGATCGATGGAATCGATATTGACTATGAGTACCCTACATCGATGCAGGATGCAGGGAATCCG
GCAGATTGGAACATCGCCAATCCGCGGCGCAACGGGTTAAATAAAAGCTTTGAGGCATTGATGAAAACATTAAGAGAAAA
GCTTGATCAAGCGTCCGCTGAAGATGGAAAGTACTACATGCTGACCATTGCAGCACCATCCTCGGCATATTTACTGAGGG
GGATGGAAACGTTTAAGCCGCTTCGATATGTCGATTATGTCAATATCATGTCCTACGATCTTCATGGAGCCTGGAATGAG
TTTGTCGGACCGAACGCTTCTTTATTCGATAACGGCGAAGATGCCGAACTCAAGCAGTCCAACATTTATACTACGCCGGA
ATACGAAGGGATCGGATATTTAAATACGGACTGGGCTTACCATTATTTTAGAGGGGCAGTAGAATCGGGACGAATCAATA
TCGGTGTGCCTTATTATACGAGAGGCTGGAAAAATGTGACCGGCGGAGCAAATGGGCTGTGGGGAAGAGCCAAAAGCGCA
GATTGCCCTCAGGGACTCAGGCAATGCGGTGACGGAGCAACCGGAATCGATAATATTTGGCACGATAAAGATGAGCAGGG
GAATGAAATTGGAGCAGGGGCAAACCCGATGTGGCACGCCAAAAACCTTGAAAAGGGCATTGCTGGTTCTTATCTGGAAA
GGTATGGATTGAGCAAGGCTGATTTGACAGGCGTTTATAAAAGGCATTATGACGCAGGGCTGGCAGCGCCTTGGCTTTGG
AATCCAGAAAAGAAAGTATTTCTATCGACAGAGGATGAGGAATCGATCAAAACGAAGGCGGATTATGTCATTGATAAAGG
AATCGGGGGTGTCATGTTTTGGGATTTGAGCGGTGATTATGACTGGTATCCCGAACGAAACGGCAGTAAAGGAGAATACG
GTATCGGCAATACCTTAACGAGAACGATGTATCATAAATTCTCGGATACAACACCATACGATAATCGACTCAGCACATCA
CCTTTGCCTGATGAATCACTAGATGCAGAAGTAGAGTTGACGAACTTTCCGTTAGGAGATCAAAATTACCCGATCCACCC
GGTGATGAAGCTGATCAACAACAGCGATGTCACGATTACGGGAGGTTCTTTTATCGAATTTGATGCGCCGACATCCACTT
CCCCTCGGTTTAGAAGCTGGAGCGGCGATCATGTTGAAGTGATTTCTAAAGGGCATACGGGACCGAACATTGGCGGACTG
ACAGTAGATTTCCACCGCATCAGAGTGACTCTATCAATCTGGAAAACCATTAAACCTGGTGAGGAAGCGGAGTTTCAGCT
TGTCTATTATTTGCCGATCAGCGGTCCTTCAAATTTCACGATATCAATAGATGGCAAAAAGTACAGGCTTAAAGGAAATT
AA

Upstream 100 bases:

>100_bases
CTGCGAATAAGAGAAAGTCAAATGGATAGAAAACGATAAAGAGAGATTTGGGGAACAGCTTCTCACGTCTCTCTTTATGG
ACAAAGGAGTCTGAGTAAAC

Downstream 100 bases:

>100_bases
GTATACGGCCGTTAGATGTGACAGCCCGTTCCAAAAGGAAGCGGGCTGTCTTCGTGTATTATTGTGCGCTGTTTTTCCAG
TTGGTCAAATTGTCGAACAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKKAASSFLSCMLLLALFIPNRQISAETSSERPDCRPEGLWDSGVEHVPYCDVYDKDGREKLANQLDRRIIGYFTSWRTG
KGNQDRYLVSDIPWKYLSHINYAFAHIGEDHRISVGEEADENNPSIGMTWPEHPDVKMDQTLPYKGHFNLIHQYKDRYPD
VKVLAAVGGWAETGGYVDKDGKRIPSGGFYSMTTNGDGSVNHKGIHTFAESVVAFLRKYEIDGIDIDYEYPTSMQDAGNP
ADWNIANPRRNGLNKSFEALMKTLREKLDQASAEDGKYYMLTIAAPSSAYLLRGMETFKPLRYVDYVNIMSYDLHGAWNE
FVGPNASLFDNGEDAELKQSNIYTTPEYEGIGYLNTDWAYHYFRGAVESGRINIGVPYYTRGWKNVTGGANGLWGRAKSA
DCPQGLRQCGDGATGIDNIWHDKDEQGNEIGAGANPMWHAKNLEKGIAGSYLERYGLSKADLTGVYKRHYDAGLAAPWLW
NPEKKVFLSTEDEESIKTKADYVIDKGIGGVMFWDLSGDYDWYPERNGSKGEYGIGNTLTRTMYHKFSDTTPYDNRLSTS
PLPDESLDAEVELTNFPLGDQNYPIHPVMKLINNSDVTITGGSFIEFDAPTSTSPRFRSWSGDHVEVISKGHTGPNIGGL
TVDFHRIRVTLSIWKTIKPGEEAEFQLVYYLPISGPSNFTISIDGKKYRLKGN

Sequences:

>Translated_693_residues
MKKAASSFLSCMLLLALFIPNRQISAETSSERPDCRPEGLWDSGVEHVPYCDVYDKDGREKLANQLDRRIIGYFTSWRTG
KGNQDRYLVSDIPWKYLSHINYAFAHIGEDHRISVGEEADENNPSIGMTWPEHPDVKMDQTLPYKGHFNLIHQYKDRYPD
VKVLAAVGGWAETGGYVDKDGKRIPSGGFYSMTTNGDGSVNHKGIHTFAESVVAFLRKYEIDGIDIDYEYPTSMQDAGNP
ADWNIANPRRNGLNKSFEALMKTLREKLDQASAEDGKYYMLTIAAPSSAYLLRGMETFKPLRYVDYVNIMSYDLHGAWNE
FVGPNASLFDNGEDAELKQSNIYTTPEYEGIGYLNTDWAYHYFRGAVESGRINIGVPYYTRGWKNVTGGANGLWGRAKSA
DCPQGLRQCGDGATGIDNIWHDKDEQGNEIGAGANPMWHAKNLEKGIAGSYLERYGLSKADLTGVYKRHYDAGLAAPWLW
NPEKKVFLSTEDEESIKTKADYVIDKGIGGVMFWDLSGDYDWYPERNGSKGEYGIGNTLTRTMYHKFSDTTPYDNRLSTS
PLPDESLDAEVELTNFPLGDQNYPIHPVMKLINNSDVTITGGSFIEFDAPTSTSPRFRSWSGDHVEVISKGHTGPNIGGL
TVDFHRIRVTLSIWKTIKPGEEAEFQLVYYLPISGPSNFTISIDGKKYRLKGN
>Mature_693_residues
MKKAASSFLSCMLLLALFIPNRQISAETSSERPDCRPEGLWDSGVEHVPYCDVYDKDGREKLANQLDRRIIGYFTSWRTG
KGNQDRYLVSDIPWKYLSHINYAFAHIGEDHRISVGEEADENNPSIGMTWPEHPDVKMDQTLPYKGHFNLIHQYKDRYPD
VKVLAAVGGWAETGGYVDKDGKRIPSGGFYSMTTNGDGSVNHKGIHTFAESVVAFLRKYEIDGIDIDYEYPTSMQDAGNP
ADWNIANPRRNGLNKSFEALMKTLREKLDQASAEDGKYYMLTIAAPSSAYLLRGMETFKPLRYVDYVNIMSYDLHGAWNE
FVGPNASLFDNGEDAELKQSNIYTTPEYEGIGYLNTDWAYHYFRGAVESGRINIGVPYYTRGWKNVTGGANGLWGRAKSA
DCPQGLRQCGDGATGIDNIWHDKDEQGNEIGAGANPMWHAKNLEKGIAGSYLERYGLSKADLTGVYKRHYDAGLAAPWLW
NPEKKVFLSTEDEESIKTKADYVIDKGIGGVMFWDLSGDYDWYPERNGSKGEYGIGNTLTRTMYHKFSDTTPYDNRLSTS
PLPDESLDAEVELTNFPLGDQNYPIHPVMKLINNSDVTITGGSFIEFDAPTSTSPRFRSWSGDHVEVISKGHTGPNIGGL
TVDFHRIRVTLSIWKTIKPGEEAEFQLVYYLPISGPSNFTISIDGKKYRLKGN

Specific function: Hydrolyzes chitin oligosaccharides; (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5,6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin, glucosamine oligosaccharides, glycoproteins and glycopeptides containing (GlcNAc)2 [H]

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 18 family [H]

Homologues:

Organism=Homo sapiens, GI4502809, Length=478, Percent_Identity=24.4769874476987, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI133893286, Length=318, Percent_Identity=26.4150943396226, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI58386720, Length=340, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI144226251, Length=326, Percent_Identity=26.0736196319018, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI42542398, Length=181, Percent_Identity=30.3867403314917, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI68533253, Length=479, Percent_Identity=19.2066805845511, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI68533255, Length=479, Percent_Identity=19.2066805845511, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71995504, Length=532, Percent_Identity=26.3157894736842, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17559362, Length=475, Percent_Identity=24.8421052631579, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17563680, Length=464, Percent_Identity=24.3534482758621, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17551250, Length=450, Percent_Identity=22.4444444444444, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17535569, Length=407, Percent_Identity=23.5872235872236, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320579, Length=440, Percent_Identity=24.3181818181818, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330815, Length=480, Percent_Identity=23.3333333333333, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI45550474, Length=462, Percent_Identity=23.8095238095238, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21358195, Length=506, Percent_Identity=22.3320158102767, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24655584, Length=325, Percent_Identity=25.8461538461538, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221329807, Length=456, Percent_Identity=20.8333333333333, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI161077700, Length=459, Percent_Identity=20.9150326797386, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI116007452, Length=314, Percent_Identity=25.1592356687898, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI22024049, Length=267, Percent_Identity=25.8426966292135, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003610
- InterPro:   IPR009470
- InterPro:   IPR011583
- InterPro:   IPR001223
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF02839 CBM_5_12; PF06483 ChiC; PF00704 Glyco_hydro_18 [H]

EC number: =3.2.1.14 [H]

Molecular weight: Translated: 77804; Mature: 77804

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAASSFLSCMLLLALFIPNRQISAETSSERPDCRPEGLWDSGVEHVPYCDVYDKDGRE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
KLANQLDRRIIGYFTSWRTGKGNQDRYLVSDIPWKYLSHINYAFAHIGEDHRISVGEEAD
HHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCCC
ENNPSIGMTWPEHPDVKMDQTLPYKGHFNLIHQYKDRYPDVKVLAAVGGWAETGGYVDKD
CCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHHCCCEECCC
GKRIPSGGFYSMTTNGDGSVNHKGIHTFAESVVAFLRKYEIDGIDIDYEYPTSMQDAGNP
CCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCCCC
ADWNIANPRRNGLNKSFEALMKTLREKLDQASAEDGKYYMLTIAAPSSAYLLRGMETFKP
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCHHHHCC
LRYVDYVNIMSYDLHGAWNEFVGPNASLFDNGEDAELKQSNIYTTPEYEGIGYLNTDWAY
HHHHEEHEEEEEECCCCHHHHCCCCCCCCCCCCCCCEECCCCEECCCCCCCCEECCCHHH
HYFRGAVESGRINIGVPYYTRGWKNVTGGANGLWGRAKSADCPQGLRQCGDGATGIDNIW
HHHHCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHC
HDKDEQGNEIGAGANPMWHAKNLEKGIAGSYLERYGLSKADLTGVYKRHYDAGLAAPWLW
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEE
NPEKKVFLSTEDEESIKTKADYVIDKGIGGVMFWDLSGDYDWYPERNGSKGEYGIGNTLT
CCCCEEEEECCCHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
RTMYHKFSDTTPYDNRLSTSPLPDESLDAEVELTNFPLGDQNYPIHPVMKLINNSDVTIT
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEE
GGSFIEFDAPTSTSPRFRSWSGDHVEVISKGHTGPNIGGLTVDFHRIRVTLSIWKTIKPG
CCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEECCCCC
EEAEFQLVYYLPISGPSNFTISIDGKKYRLKGN
CCCCEEEEEEEECCCCCCEEEEECCEEEEECCC
>Mature Secondary Structure
MKKAASSFLSCMLLLALFIPNRQISAETSSERPDCRPEGLWDSGVEHVPYCDVYDKDGRE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
KLANQLDRRIIGYFTSWRTGKGNQDRYLVSDIPWKYLSHINYAFAHIGEDHRISVGEEAD
HHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCCC
ENNPSIGMTWPEHPDVKMDQTLPYKGHFNLIHQYKDRYPDVKVLAAVGGWAETGGYVDKD
CCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCHHHCCCEECCC
GKRIPSGGFYSMTTNGDGSVNHKGIHTFAESVVAFLRKYEIDGIDIDYEYPTSMQDAGNP
CCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCCCC
ADWNIANPRRNGLNKSFEALMKTLREKLDQASAEDGKYYMLTIAAPSSAYLLRGMETFKP
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHCHHHHCC
LRYVDYVNIMSYDLHGAWNEFVGPNASLFDNGEDAELKQSNIYTTPEYEGIGYLNTDWAY
HHHHEEHEEEEEECCCCHHHHCCCCCCCCCCCCCCCEECCCCEECCCCCCCCEECCCHHH
HYFRGAVESGRINIGVPYYTRGWKNVTGGANGLWGRAKSADCPQGLRQCGDGATGIDNIW
HHHHCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHC
HDKDEQGNEIGAGANPMWHAKNLEKGIAGSYLERYGLSKADLTGVYKRHYDAGLAAPWLW
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEE
NPEKKVFLSTEDEESIKTKADYVIDKGIGGVMFWDLSGDYDWYPERNGSKGEYGIGNTLT
CCCCEEEEECCCHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
RTMYHKFSDTTPYDNRLSTSPLPDESLDAEVELTNFPLGDQNYPIHPVMKLINNSDVTIT
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEE
GGSFIEFDAPTSTSPRFRSWSGDHVEVISKGHTGPNIGGLTVDFHRIRVTLSIWKTIKPG
CCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEECCCCC
EEAEFQLVYYLPISGPSNFTISIDGKKYRLKGN
CCCCEEEEEEEECCCCCCEEEEECCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969204 [H]